Molecular Modeling Studies on the Chiral Separation of (±)-Catechins by Mono-succinyl-β-cyclodextrin

Chiral separation is a subject of great interest in the development, use, and action of pharmaceutical agents. Chiral pharmaceutical compounds typically have different pharmacological and toxicological properties, and therefore the quantitative chiral composition of these compounds should be determined. 1 The catechin discussed in this work belongs to the group of polyphenols, which are represented by the class of flavan-3-ols. The flavan-3-ols show notable physiological effects, including antioxidant, antimicrobial, and anticarcinogenic activities.

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