Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation.
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R. Bartrons | J. Duran | M. Obach | À. Navarro-Sabaté | A. Manzano | Marta Gómez | J. C. Perales | Lluís Riera-Sans
[1] R. Bartrons,et al. Overexpression of ubiquitous 6-phosphofructo-2-kinase in the liver of transgenic mice results in weight gain. , 2008, Biochemical and biophysical research communications.
[2] E. Schaftingen. Fructose 2,6-bisphosphate. , 2006 .
[3] R. Bartrons,et al. PFKFB3 gene silencing decreases glycolysis, induces cell‐cycle delay and inhibits anchorage‐independent growth in HeLa cells , 2006, FEBS letters.
[4] A. Yalçin,et al. Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality. , 2005, Biochemical and biophysical research communications.
[5] J. L. Rosa,et al. 6-Phosphofructo-2-kinase (pfkfb3) Gene Promoter Contains Hypoxia-inducible Factor-1 Binding Sites Necessary for Transactivation in Response to Hypoxia* , 2004, Journal of Biological Chemistry.
[6] D. Vertommen,et al. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. , 2004, The Biochemical journal.
[7] D. Waxman,et al. Impact of dimethyl sulfoxide on expression of nuclear receptors and drug-inducible cytochromes P450 in primary rat hepatocytes. , 2004, Archives of biochemistry and biophysics.
[8] J. Fassett,et al. The Role of Collagen Structure in Mitogen Stimulation of ERK, Cyclin D1 Expression, and G1-S Progression in Rat Hepatocytes* , 2003, Journal of Biological Chemistry.
[9] D. Gilot,et al. PI3K‐FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival , 2002, Hepatology.
[10] L. Leng,et al. High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. , 2002, Cancer research.
[11] R. Bartrons,et al. Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells. , 2002, Biochimica et biophysica acta.
[12] N. Sang,et al. Hypoxia-inducible Factor-1-mediated Expression of the 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) Gene , 2002, The Journal of Biological Chemistry.
[13] A. Dickson,et al. Expression of CCAAT/enhancer binding protein family genes in monolayer and sandwich culture of hepatocytes: induction of stress-inducible GADD153. , 2001, Biochemical and biophysical research communications.
[14] K. Eschrich,et al. Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain. , 2001, Brain research. Molecular brain research.
[15] J. L. Rosa,et al. The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure. , 2001, Gene.
[16] F. Ventura,et al. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase expression in rat brain during development. , 2000, Brain research. Molecular brain research.
[17] C. Mounier,et al. Epidermal Growth Factor and Insulin-Induced Deoxyribonucleic Acid Synthesis in Primary Rat Hepatocytes Is Phosphatidylinositol 3-Kinase Dependent and Dissociated from Protooncogene Induction1. , 1999, Endocrinology.
[18] E. Furuya,et al. Tissue‐specific alternative splicing of rat brain fructose 6‐phosphate 2‐kinase/fructose 2,6‐bisphosphatase , 1999, FEBS letters.
[19] R. Bucala,et al. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[20] X. Estivill,et al. Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase gene (PFKFB3) , 1999, Cytogenetic and Genome Research.
[21] Akiko Sakai,et al. Novel Isoforms of Rat Brain Fructose 6‐Phosphate 2‐Kinase/Fructose 2,6‐Bisphosphatase Are Generated by Tissue‐Specific Alternative Splicing , 1997, Journal of neurochemistry.
[22] R. Sakakibara,et al. Characterization of a human placental fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase. , 1997, Journal of biochemistry.
[23] J. A. Hamilton,et al. Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. , 1997, Molecular endocrinology.
[24] R. Sakakibara,et al. Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta. , 1996, Journal of biochemistry.
[25] L. Boscá,et al. Multiple forms of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase are expressed in perinatal rat liver. , 1996, The American journal of physiology.
[26] F. Ventura,et al. Cloning and expression of a catalytic core bovine brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. , 1995, Biochemical and biophysical research communications.
[27] R. Bartrons,et al. Hormonal control of fructose 2,6-bisphosphate concentration in isolated rat hepatocytes. , 1983, The Biochemical journal.
[28] S. Khan,et al. Roles for fructose-2,6-bisphosphate in the control of fuel metabolism: beyond its allosteric effects on glycolytic and gluconeogenic enzymes. , 2006, Advances in enzyme regulation.
[29] R. Bartrons,et al. PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate. , 2001, Trends in biochemical sciences.
[30] I. Kurland,et al. 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme. , 1995, Annual review of biochemistry.