Hydrogel‐Based Artificial Mucosa Restores Local Immune and Microbial Homeostasis for Treating Ulcerative Colitis

[1]  Hu Xu,et al.  Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal. , 2022, Cell stem cell.

[2]  Zhengbao Zha,et al.  Ultrathin Hafnium Disulfide Atomic Crystals with ROS-Scavenging and Colon-Targeting Capabilities for Inflammatory Bowel Disease Treatment. , 2022, ACS nano.

[3]  Zhenzhong Zhang,et al.  Bionic Regulators Break the Ecological Niche of Pathogenic Bacteria for Modulating Dysregulated Microbiome in Colitis , 2022, Advanced materials.

[4]  Dingcai Wu,et al.  Peritoneum‐Inspired Janus Porous Hydrogel with Anti‐Deformation, Anti‐Adhesion, and Pro‐Healing Characteristics for Abdominal Wall Defect Treatment , 2022, Advanced materials.

[5]  Fangzhou Song,et al.  Treating Autoimmune Inflammatory Diseases with an siERN1-Nanoprodrug That Mediates Macrophage Polarization and Blocks Toll-like Receptor Signaling. , 2021, ACS nano.

[6]  Yuliang Zhao,et al.  Colonic mucus-accumulating tungsten oxide nanoparticles improve the colitis therapy by targeting Enterobacteriaceae , 2021, Nano Today.

[7]  L. Deng,et al.  Colon‐Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora , 2021, Advanced science.

[8]  Qihui Zhou,et al.  Bio‐Multifunctional Hydrogel Patches for Repairing Full‐Thickness Abdominal Wall Defects , 2021, Advanced Functional Materials.

[9]  R. Sartor,et al.  Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis , 2021, Nature Communications.

[10]  T. Taguchi,et al.  Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis , 2021, Advanced Functional Materials.

[11]  M. Kalady,et al.  Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome , 2021, Signal Transduction and Targeted Therapy.

[12]  Yuliang Cheng,et al.  In-depth analysis of the mechanisms of aloe polysaccharides on mitigating subacute colitis in mice via microbiota informatics. , 2021, Carbohydrate polymers.

[13]  Wei Cheng,et al.  Injectable antibacterial antiinflammatory molecular hybrid hydrogel dressing for rapid MDRB-infected wound repair and therapy , 2021 .

[14]  B. Sands,et al.  New Therapeutics for Ulcerative Colitis. , 2021, Annual review of medicine.

[15]  Lin Zhou,et al.  Hyaluronic acid thiol modified injectable hydrogel: Synthesis, characterization, drug release, cellular drug uptake and anticancer activity. , 2020, Carbohydrate polymers.

[16]  W. Cui,et al.  Improving drug utilization platform with injectable mucoadhesive hydrogel for treating ulcerative colitis , 2021 .

[17]  D. Fruman,et al.  YAP-mediated mechanotransduction tunes the macrophage inflammatory response , 2020, Science Advances.

[18]  Qijuan Yuan,et al.  Arginine derivatives assist dopamine-hyaluronic acid hybrid hydrogels to have enhanced antioxidant activity for wound healing , 2020 .

[19]  Qiang Zhao,et al.  IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE2-mediated M2 macrophage polarization , 2020, Theranostics.

[20]  Zhengquan Yu,et al.  TCF-1 deficiency influences the composition of intestinal microbiota and enhances susceptibility to colonic inflammation , 2020, Protein & Cell.

[21]  Qiqing Zhang,et al.  Dynamic covalent constructed self-healing hydrogel for sequential delivery of antibacterial agent and growth factor in wound healing , 2019, Chemical Engineering Journal.

[22]  M. Neurath,et al.  Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. , 2019, Immunity.

[23]  J. Moon,et al.  Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis. , 2019, Nature Materials.

[24]  H. Vlamakis,et al.  Microbial genes and pathways in inflammatory bowel disease , 2019, Nature Reviews Microbiology.

[25]  C. Lengner,et al.  MicroRNA-31 Reduces Inflammatory Signaling and Promotes Regeneration in Colon Epithelium, and Delivery of Mimics in Microspheres Reduces Colitis in Mice. , 2019, Gastroenterology.

[26]  Colin J. Brislawn,et al.  Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases , 2019, Nature.

[27]  Y. Tabata,et al.  Preparation of fibrin hydrogels to promote the recruitment of anti-inflammatory macrophages. , 2019, Acta biomaterialia.

[28]  A. Wolberg,et al.  Fibrinogen and fibrin: An illustrated review , 2019, Research and practice in thrombosis and haemostasis.

[29]  R. Miron,et al.  Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells. , 2019, Journal of biomedical materials research. Part A.

[30]  A. Abbaspourrad,et al.  A Microfluidic‐Based Model for Spatially Constrained Culture of Intestinal Microbiota , 2018, Advanced Functional Materials.

[31]  R. Curi,et al.  Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation , 2018, Nutrients.

[32]  Yingwei Chen,et al.  Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury , 2018, EBioMedicine.

[33]  K. S. Siddiqi,et al.  A review on biosynthesis of silver nanoparticles and their biocidal properties , 2018, Journal of Nanobiotechnology.

[34]  Andrew Y. Koh,et al.  Precision editing of the gut microbiota ameliorates colitis , 2018, Nature.

[35]  J. Clemente,et al.  Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice. , 2017, Gastroenterology.

[36]  E. Prochownik,et al.  miR-148a inhibits colitis and colitis-associated tumorigenesis in mice , 2017, Cell Death and Differentiation.

[37]  P. Chu,et al.  Photo-Inspired Antibacterial Activity and Wound Healing Acceleration by Hydrogel Embedded with Ag/Ag@AgCl/ZnO Nanostructures. , 2017, ACS nano.

[38]  H. Kiyono,et al.  Mucosal Ecological Network of Epithelium and Immune Cells for Gut Homeostasis and Tissue Healing. , 2017, Annual review of immunology.

[39]  C. Huttenhower,et al.  Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease , 2016, Gut.

[40]  R. Xavier,et al.  CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands , 2016, Nature Medicine.

[41]  Y. Izumi,et al.  Randomized Placebo‐Controlled and Controlled Non‐Inferiority Phase III Trials Comparing Trafermin, a Recombinant Human Fibroblast Growth Factor 2, and Enamel Matrix Derivative in Periodontal Regeneration in Intrabony Defects , 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[42]  C. Fiocchi,et al.  Immunopathogenesis of IBD: current state of the art , 2016, Nature Reviews Gastroenterology &Hepatology.

[43]  Megan Cully Inflammatory diseases: Hydrogel drug delivery for inflammatory bowel disease , 2015, Nature Reviews Drug Discovery.

[44]  Robert Langer,et al.  An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease , 2015, Science Translational Medicine.

[45]  Xiaofei Xu,et al.  Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization , 2014, Cellular and Molecular Immunology.

[46]  Dean P. Jones,et al.  Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in critically ill surgical patients. , 2008, JPEN. Journal of parenteral and enteral nutrition.

[47]  Y. Tabata,et al.  Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis. , 2005, Gastroenterology.

[48]  R. Lyons Thiol – Vitamin K Mechanism in the Clotting of Fibrinogen , 1945, Nature.