c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis
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Xu Guang Yan | R. Scott | Yongyan Wu | S. Guo | Lei Jin | Xu Dong Zhang | R. Thorne | Wei Gao | Ting La | Tao Liu | Xiao Ying Liu | L. Teng | Y. Feng | Qiang Ji | Jin Ming Li | Y. Zhang | H. Tabatabaee | M Fairuz B Jamaluddin | Didi Zhang | X. Yan | R. Scott | R. Scott
[1] Xu Dong Zhang,et al. SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms , 2020, Nucleic acids research.
[2] R. Scott,et al. LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription , 2019, Nature Communications.
[3] O. Tokgun,et al. MYC-driven regulation of long non-coding RNA profiles in breast cancer cells. , 2019, Gene.
[4] Junnian Zheng,et al. Emerging Roles of p53 Related lncRNAs in Cancer Progression: A Systematic Review , 2019, International journal of biological sciences.
[5] V. Serra,et al. Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs , 2019, Molecular Cancer Therapeutics.
[6] S. Guo,et al. Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence , 2018, Proceedings of the National Academy of Sciences.
[7] National Health and Medical Research Council (NHMRC) , 2018, The Grants Register 2022.
[8] S. Guo,et al. A p53-Responsive miRNA Network Promotes Cancer Cell Quiescence. , 2018, Cancer research.
[9] Lei Jin,et al. GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability , 2018, Nature Cell Biology.
[10] Lei Jin,et al. LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect , 2018, Proceedings of the National Academy of Sciences.
[11] Xu Guang Yan,et al. Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress. , 2017, Cancer research.
[12] Scott W. Lowe,et al. Putting p53 in Context , 2017, Cell.
[13] I. Iaccarino. lncRNAs and MYC: An Intricate Relationship , 2017, International journal of molecular sciences.
[14] R. Fåhraeus,et al. p53 binds the mdmx mRNA and controls its translation , 2017, Oncogene.
[15] Maite Huarte,et al. A Long Noncoding RNA Regulates Sister Chromatid Cohesion. , 2016, Molecular cell.
[16] Howard Y. Chang,et al. Long Noncoding RNAs in Cancer Pathways. , 2016, Cancer cell.
[17] Jianrong Li,et al. Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells , 2015, Nucleic Acids Res..
[18] Maite Huarte. The emerging role of lncRNAs in cancer , 2015, Nature Medicine.
[19] A. Kasza,et al. Simultaneous detection of mRNA and protein in single cells using immunofluorescence-combined single-molecule RNA FISH. , 2015, BioTechniques.
[20] Yan Zhou,et al. Identification of TRIML2, a Novel p53 Target, that Enhances p53 SUMOylation and Regulates the Transactivation of Proapoptotic Genes , 2014, Molecular Cancer Research.
[21] Xiaoqiang Guo,et al. The lncRNA-MYC regulatory network in cancer , 2014, Tumor Biology.
[22] M. Neil,et al. Absolute quantification of protein copy number using a single-molecule-sensitive microarray. , 2014, The Analyst.
[23] D. Felsher,et al. MYC activation is a hallmark of cancer initiation and maintenance. , 2014, Cold Spring Harbor perspectives in medicine.
[24] L. Girard,et al. Nullifying the CDKN2AB Locus Promotes Mutant K-ras Lung Tumorigenesis , 2014, Molecular Cancer Research.
[25] Sanjeev Das,et al. HDAC5, a key component in temporal regulation of p53-mediated transactivation in response to genotoxic stress. , 2013, Molecular cell.
[26] C. Dang. MYC, metabolism, cell growth, and tumorigenesis. , 2013, Cold Spring Harbor perspectives in medicine.
[27] David E. Muench,et al. c-Myc and Cancer Metabolism , 2012, Clinical Cancer Research.
[28] Howard Y. Chang,et al. Genome regulation by long noncoding RNAs. , 2012, Annual review of biochemistry.
[29] Chi V Dang,et al. MYC on the Path to Cancer , 2012, Cell.
[30] E. Mohammadi,et al. Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.
[31] Peter F. Stadler,et al. ViennaRNA Package 2.0 , 2011, Algorithms for Molecular Biology.
[32] J. Ellenberg,et al. The quantitative proteome of a human cell line , 2011, Molecular systems biology.
[33] Sekhar Duraisamy,et al. Classifying variants of CDKN2A using computational and laboratory studies , 2011, Human mutation.
[34] Wei Gu,et al. p53 post-translational modification: deregulated in tumorigenesis. , 2010, Trends in molecular medicine.
[35] W. Gu,et al. New insights into p53 activation , 2010, Cell Research.
[36] C. Anderson,et al. Posttranslational modification of p53: cooperative integrators of function. , 2009, Cold Spring Harbor perspectives in biology.
[37] S. Lowe,et al. Tumor suppressive functions of p53. , 2009, Cold Spring Harbor perspectives in biology.
[38] C. Dang,et al. MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities , 2009, Clinical Cancer Research.
[39] Zhuohua Zhang,et al. Detection of protein ubiquitination. , 2009, Journal of visualized experiments : JoVE.
[40] Y. Mo,et al. p53 and c-myc: How does the cell balance “yin” and “yang”? , 2009, Cell cycle.
[41] Hailong Wu,et al. p53 represses c-Myc through induction of the tumor suppressor miR-145 , 2009, Proceedings of the National Academy of Sciences.
[42] Minoru Yoshida,et al. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. , 2009, Chemistry & biology.
[43] G. Evan,et al. Distinct thresholds govern Myc's biological output in vivo. , 2008, Cancer cell.
[44] H. Reichardt,et al. Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats , 2008, Proceedings of the National Academy of Sciences.
[45] W. Jiang,et al. NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress. , 2008, Current cancer drug targets.
[46] O. Perez,et al. Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. , 2008, Cancer research.
[47] R. Deng,et al. p14ARF sensitizes human osteosarcoma cells to cisplatin-induced apoptosis in a p53-independent manner , 2007, Cancer biology & therapy.
[48] J. Weber,et al. Therapeutic targets in the ARF tumor suppressor pathway. , 2007, Current medicinal chemistry.
[49] M. Dai,et al. Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc. , 2006, Neoplasia.
[50] Kathryn A. O’Donnell,et al. The c-Myc target gene network. , 2006, Seminars in cancer biology.
[51] John Jeremy Rice,et al. A plausible model for the digital response of p53 to DNA damage. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[52] Weili Ma,et al. p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest , 2005, Molecular and Cellular Biology.
[53] J. Kench,et al. p14ARF Protein Expression Is a Predictor of Both Relapse and Survival in Squamous Cell Carcinoma of the Anterior Tongue , 2005, Clinical Cancer Research.
[54] Zigang Dong,et al. Post-translational modification of p53 in tumorigenesis , 2004, Nature Reviews Cancer.
[55] Peggy J. Farnham,et al. Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression , 2003, Current Biology.
[56] S. Lowe,et al. Tumor suppression by Ink4a-Arf: progress and puzzles. , 2003, Current opinion in genetics & development.
[57] S. Lowe,et al. Dissecting p53 tumor suppressor functions in vivo. , 2002, Cancer cell.
[58] G. Evan,et al. Proliferation, cell cycle and apoptosis in cancer , 2001, Nature.
[59] R. Hay,et al. SUMO-1 Conjugation in Vivo Requires Both a Consensus Modification Motif and Nuclear Targeting* , 2001, The Journal of Biological Chemistry.
[60] F. Bosman,et al. Methylation Silencing and Mutations of the p14ARF and p16INK4a Genes in Colon Cancer , 2001, Laboratory Investigation.
[61] B. Kempkes,et al. Cell cycle activation by c‐myc in a Burkitt lymphoma model cell line , 2000, International journal of cancer.
[62] R. Blamey,et al. INK4a gene expression and methylation in primary breast cancer: overexpression of p16INK4a messenger RNA is a marker of poor prognosis. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[63] M. Roussel,et al. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. , 1999, Genes & development.
[64] Chi V. Dang,et al. c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism , 1999, Molecular and Cellular Biology.
[65] J L Cleveland,et al. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. , 1998, Genes & development.
[66] Stephen N. Jones,et al. Regulation of p53 stability by Mdm2 , 1997, Nature.
[67] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[68] H. Hermeking,et al. Mediation of c-Myc-induced apoptosis by p53. , 1994, Science.
[69] Bruno Amati,et al. Oncogenic activity of the c-Myc protein requires dimerization with Max , 1993, Cell.
[70] K. Vousden,et al. The role of ubiquitin modification in the regulation of p53. , 2014, Biochimica et biophysica acta.
[71] T. Tsunoda,et al. Morphological and microarray analyses of human hepatocytes from xenogeneic host livers , 2013, Laboratory Investigation.
[72] J. Flanagan,et al. RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. , 2012, The Journal of molecular diagnostics : JMD.
[73] R. Blamey,et al. INK 4 a Gene Expression and Methylation in Primary Breast Cancer : Overexpression of p 16 INK 4 a Messenger RNA Is a Marker of Poor Prognosis 1 , 2000 .
[74] D. Marlowe. Progress and Puzzles. , 1967 .