A 16-bit parallel processing in a molecular assembly

A machine assembly consisting of 17 identical molecules of 2,3,5,6-tetramethyl-1–4-benzoquinone (DRQ) executes 16 instructions at a time. A single DRQ is positioned at the center of a circular ring formed by 16 other DRQs, controlling their operation in parallel through hydrogen-bond channels. Each molecule is a logic machine and generates four instructions by rotating its alkyl groups. A single instruction executed by a scanning tunneling microscope tip on the central molecule can change decisions of 16 machines simultaneously, in four billion (416) ways. This parallel communication represents a significant conceptual advance relative to today's fastest processors, which execute only one instruction at a time.

[1]  K. Mislow,et al.  Stereochemical consequences of dynamic gearing in substituted bis(9-triptycyl) methanes and related molecules. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[2]  F. L. Carter Molecular Electronic Devices II , 1987 .

[3]  H. Nejoh,et al.  Anisotropic Standing-Wave Formation on an Au(111)-(23×√3)Reconstructed Surface , 1997 .

[4]  Ho,et al.  Inducing and viewing the rotational motion of a single molecule , 1998, Science.

[5]  K. Drexler,et al.  Building molecular machine systems , 1999 .

[6]  A. Mehta,et al.  Single-molecule biomechanics with optical methods. , 1999, Science.

[7]  N. Harada,et al.  Light-driven monodirectional molecular rotor , 2022 .

[8]  J. F. Stoddart,et al.  A [2]Catenane-Based Solid State Electronically Reconfigurable Switch , 2000 .

[9]  H. Craighead,et al.  Powering an inorganic nanodevice with a biomolecular motor. , 2000, Science.

[10]  G. Oster,et al.  The physics of molecular motors. , 2001, Accounts of chemical research.

[11]  N. Seeman,et al.  A robust DNA mechanical device controlled by hybridization topology , 2002, Nature.

[12]  James M Tour,et al.  En route to surface-bound electric field-driven molecular motors. , 2003, The Journal of organic chemistry.

[13]  Yuyuan Tian,et al.  Measurement of Single-Molecule Resistance by Repeated Formation of Molecular Junctions , 2003, Science.

[14]  J. Fraser Stoddart,et al.  A Molecular Elevator , 2004, Science.

[15]  Viola Vogel,et al.  Powering nanodevices with biomolecular motors. , 2004, Chemistry.

[16]  Michael M. Pollard,et al.  A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy , 2005, Science.

[17]  N. Seeman,et al.  Operation of a DNA Robot Arm Inserted into a 2D DNA Crystalline Substrate , 2006, Science.

[18]  Wesley R Browne,et al.  Making molecular machines work , 2006, Nature nanotechnology.

[19]  David A. Leigh,et al.  Photochemistry: Lighting up nanomachines , 2006, Nature.

[20]  T. Lithgow,et al.  Evolution of the Molecular Machines for Protein Import into Mitochondria , 2006, Science.

[21]  Anirban Bandyopadhyay,et al.  Writing and erasing information in multilevel logic systems of a single molecule using scanning tunneling microscope , 2006 .

[22]  M. Garcia‐Garibay,et al.  Crystalline molecular machines: a quest toward solid-state dynamics and function. , 2006, Accounts of chemical research.

[23]  A. Bandyopadhyay,et al.  Mechanism of conductance switching: an optical investigation , 2006 .

[24]  A. Bandyopadhyay,et al.  Fabrication of a Memory Chip by a Complete Self‐Assembly Process Using State‐of‐the‐Art Multilevel Cell (MLC) Technology , 2008 .