Differential expression of interleukin 1 receptor antagonist isoforms in human intestinal epithelial cells.

[1]  C. Moskaluk,et al.  IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. , 1998, Journal of immunology.

[2]  L. Eckmann,et al.  The regulation and functional consequence of proinflammatory cytokine binding on human intestinal epithelial cells. , 1998, Journal of immunology.

[3]  S. Hollerbach,et al.  Imbalance of the interleukin 1 system in colonic mucosa—association with intestinal inflammation and interleukin 1 receptor agonist genotype 2 , 1997 .

[4]  J. Madara The Chameleon Within: Improving Antigen Delivery , 1997, Science.

[5]  M. Kagnoff,et al.  Epithelial cells as sensors for microbial infection. , 1997, The Journal of clinical investigation.

[6]  J. Shelhamer,et al.  Extracellular release of the type I intracellular IL-1 receptor antagonist from human airway epithelial cells: differential effects of IL-4, IL-13, IFN-gamma, and corticosteroids. , 1997, Journal of immunology.

[7]  C. Gabay,et al.  Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. , 1997, The Journal of clinical investigation.

[8]  K. Seibert,et al.  Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1. , 1997, The Journal of clinical investigation.

[9]  J. Jenkins,et al.  Intracellular IL-1 receptor antagonist promoter: cell type-specific and inducible regulatory regions. , 1997, Journal of immunology.

[10]  S. Haskill,et al.  Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells. , 1997, Journal of immunology.

[11]  S. Paul,et al.  Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[12]  J. Westwick,et al.  Inducible nitric oxide synthase activity and expression in a human colonic epithelial cell line, HT‐29 , 1995, British journal of pharmacology.

[13]  J. Olsen,et al.  The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1 beta. , 1995, Journal of immunology.

[14]  R. Sartor Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease. , 1995, Gastroenterology clinics of North America.

[15]  A. Mantovani,et al.  Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist , 1995, The Journal of experimental medicine.

[16]  L. Mayer,et al.  Synthesis and regulation of accessory/proinflammatory cytokines by intestinal epithelial cells , 1995, Clinical and experimental immunology.

[17]  A. Rubartelli,et al.  Synthesis and Secretion of Interleukin-1α and Intedeukin-1 Receptor Antagonist during Differentiation of Cultured Keratinocytes , 1995 .

[18]  C. Fiocchi,et al.  Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. , 1995, Journal of immunology.

[19]  M. Kagnoff,et al.  A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. , 1995, The Journal of clinical investigation.

[20]  A. Steinkasserer,et al.  Comparison of two promoters controlling expression of secreted or intracellular IL-1 receptor antagonist. , 1994, Journal of immunology.

[21]  C. Nast,et al.  Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis. , 1994, The Journal of clinical investigation.

[22]  A. Mantovani,et al.  Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1ra) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1ra in human myelomonocytic cells. , 1994, Blood.

[23]  R. Thompson,et al.  Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats. , 1994, Gastroenterology.

[24]  M. T. Brewer,et al.  Rabbit interleukin-1 receptor antagonist. Cloning, expression, functional characterization, and regulation during intestinal inflammation. , 1994, The Journal of biological chemistry.

[25]  J. Mansfield,et al.  Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. , 1994, Gastroenterology.

[26]  M. Kagnoff,et al.  Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. , 1993, Gastroenterology.

[27]  M. Kagnoff,et al.  Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry , 1993, Infection and immunity.

[28]  H P Bartram,et al.  Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. , 1993, Cancer research.

[29]  J. Barnard,et al.  Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[30]  G. Winterrowd,et al.  Regulation of expression of IL-1 receptor antagonist protein in human synovial and dermal fibroblasts. , 1993, Journal of immunology.

[31]  C. Dinarello,et al.  The role of interleukin-1 in disease. , 1993, The New England journal of medicine.

[32]  W. Arend Interleukin-1 receptor antagonist. , 1993, Advances in immunology.

[33]  S. Haskill,et al.  Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification. , 1992, Gastroenterology.

[34]  P. Krajči,et al.  Expression and Regulation of Adhesion Molecules ICAM‐1 (CD54) and LFA‐3 (CD58) in Human Intestinal Epithelial Cell Lines , 1992, Scandinavian journal of immunology.

[35]  A. Mantovani,et al.  Inhibitory effect of recombinant intracellular interleukin 1 receptor antagonist on endothelial cell activation. , 1992, Cytokine.

[36]  W. Scheppach,et al.  Effect of short-chain fatty acids on the human colonic mucosa in vitro. , 1992, JPEN. Journal of parenteral and enteral nutrition.

[37]  B. Dutrillaux,et al.  Dihydrofolate reductase gene amplification-associated shift of differentiation in methotrexate-adapted HT-29 cells , 1991, The Journal of cell biology.

[38]  D. Dripps,et al.  Interleukin-1 receptor antagonist binds to the type II interleukin-1 receptor on B cells and neutrophils. , 1991, The Journal of biological chemistry.

[39]  J. Revillard,et al.  Expression, function and regulation of the intercellular adhesion molecule‐1 (ICAM‐1) on human intestinal epithelial cell lines , 1991, European journal of immunology.

[40]  D. Dripps,et al.  Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction. , 1991, The Journal of biological chemistry.

[41]  S. Haskill,et al.  cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[42]  C. Dinarello Interleukin-1 and interleukin-1 antagonism. , 1991, Blood.

[43]  A. Barbat,et al.  Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells. , 1990, Cancer research.

[44]  C. J. Dunn,et al.  Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein , 1990, Nature.

[45]  M. T. Brewer,et al.  Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist , 1990, Nature.

[46]  Robert C. Thompson,et al.  Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor , 1990, Nature.

[47]  C. Hannum,et al.  An IL-1 inhibitor from human monocytes. Production and characterization of biologic properties. , 1989, Journal of immunology.

[48]  L. Mayer,et al.  Evidence for function of Ia molecules on gut epithelial cells in man , 1987, The Journal of experimental medicine.

[49]  M. Rousset,et al.  The human colon carcinoma cell lines HT-29 and Caco-2: two in vitro models for the study of intestinal differentiation. , 1986, Biochimie.

[50]  C. Laboisse,et al.  Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. , 1984, Cancer research.

[51]  M. Bookman,et al.  Isolation and functional characterization of human intestinal mucosal lymphoid cells. , 1977, The Journal of clinical investigation.