Acute Cardiovascular Consequences of Anterior Descending Coronary Artery Occlusion in Unanesthetized Monkey 1 2

Summary The acute response of the unanesthetized monkey to occlusion of the anterior descending coronary artery consists of a pressor response, tachycardia and increase in d(LVP)/dt. This response resembles that reported for comparable situations in man, and may be due to elevated cardiac sympathetic tone. Anatomical and physiological characteristics of the non-human primate suggest that these animals provide attractive models for experimental study of anterior MI.