Functional MR imaging of language, memory, and sensorimotor cortex.

fMR imaging is a versatile technology that allows for the noninvasive identification of sensory, motor,and cognitive functions that may be impaired by surgical resection. fMR imaging provides the capacity to probe several brain functions, and when results are uncertain, to repeat or modify them. There are some limitations, MR contraindications to scanning, motion, and cooperation among them. Yet for most patients fMR imaging provides a reliable way to lateralize language dominance and to guide localization of language functions. Memory paradigms lag behind language in practical application, but the impediments to its utility will likely be resolved in the near future.

[1]  Ravi S. Menon,et al.  Functional imaging of human motor cortex at high magnetic field. , 1993, Journal of neurophysiology.

[2]  W H Theodore,et al.  A direct comparison of PET activation and electrocortical stimulation mapping for language localization , 1997, Neurology.

[3]  J. Drake,et al.  Combined utility of functional MRI, cortical mapping, and frameless stereotaxy in the resection of lesions in eloquent areas of brain in children. , 1997, Pediatric neurosurgery.

[4]  J. Desmond,et al.  Material-specific lateralization in the medial temporal lobe and prefrontal cortex during memory encoding. , 2001, Brain : a journal of neurology.

[5]  Alan Connelly,et al.  A Direct Test for Lateralization of Language Activation using fMRI: Comparison with Invasive Assessments in Children with Epilepsy , 2002, NeuroImage.

[6]  William D. Gaillard,et al.  Neuroimaging Reveals Automatic Speech Coding during Perception of Written Word Meaning , 2002, NeuroImage.

[7]  M. Just,et al.  Brain Activation Modulated by Sentence Comprehension , 1996, Science.

[8]  R J Wise,et al.  Separate neural subsystems within 'Wernicke's area'. , 2001, Brain : a journal of neurology.

[9]  S. Bookheimer,et al.  15O water positron emission tomography in language localization: A study comparing positron emission tomography visual and computerized region of interest analysis with the wada test , 1999, Annals of neurology.

[10]  A Jesmanowicz,et al.  Lateralized human brain language systems demonstrated by task subtraction functional magnetic resonance imaging. , 1995, Archives of neurology.

[11]  J. Binder,et al.  Functional magnetic resonance imaging of complex human movements , 1993, Neurology.

[12]  S. Sato,et al.  Language dominance in partial epilepsy patients identified with an fMRI reading task , 2002, Neurology.

[13]  G. Ojemann,et al.  Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. , 1989, Journal of neurosurgery.

[14]  Friedrich G. Woermann,et al.  Memory fMRI lateralizes temporal lobe epilepsy , 2001, Neurology.

[15]  J. Desmond,et al.  Making memories: brain activity that predicts how well visual experience will be remembered. , 1998, Science.

[16]  J. Petrella,et al.  Cortical localization of reading in normal children , 2001, Neurology.

[17]  M. Erb,et al.  fMRI Evaluation of Somatotopic Representation in Human Primary Motor Cortex , 2000, NeuroImage.

[18]  P. Pietrini,et al.  Conjoint and extended neural networks for the computation of speech codes: the neural basis of selective impairment in reading words and pseudowords. , 2001, Cerebral cortex.

[19]  J. Petrella,et al.  Developmental aspects of language processing: fMRI of verbal fluency in children and adults , 2003, Human brain mapping.

[20]  Stéphane Lehéricy,et al.  Arteriovenous brain malformations: is functional MR imaging reliable for studying language reorganization in patients? Initial observations. , 2002, Radiology.

[21]  S. Bookheimer,et al.  The use of fMRI in neocortical epilepsy. , 2000, Advances in neurology.

[22]  G H Glover,et al.  Separate neural bases of two fundamental memory processes in the human medial temporal lobe. , 1997, Science.

[23]  J B Poline,et al.  Episodic memory in left temporal lobe epilepsy: a functional MRI study. , 2000, Brain : a journal of neurology.

[24]  A. Dale,et al.  Building memories: remembering and forgetting of verbal experiences as predicted by brain activity. , 1998, Science.

[25]  Kristina M. Visscher,et al.  Functional Neuroanatomical Differences Between Adults and School-Age Children in the Processing of Single Words , 2002, Science.

[26]  V. Haughton,et al.  Functional MR of frontal lobe activation: comparison with Wada language results. , 1998, AJNR. American journal of neuroradiology.

[27]  D. Le Bihan,et al.  Noninvasive assessment of language dominance in children and adolescents with functional MRI , 1997, Neurology.

[28]  J. B. Demb,et al.  Functional MRI measurement of language lateralization in Wada-tested patients. , 1995, Brain : a journal of neurology.

[29]  Nader Pouratian,et al.  Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations. , 2002, Journal of neurosurgery.

[30]  B Milner,et al.  THE ROLE OF EARLY LEFT‐BRAIN INJURY IN DETERMINING LATERALIZATION OF CEREBRAL SPEECH FUNCTIONS , 1977, Annals of the New York Academy of Sciences.

[31]  J. Xiong,et al.  Directly mapping magnetic field effects of neuronal activity by magnetic resonance imaging , 2003, Human brain mapping.

[32]  G. J. M. Rutten,et al.  fMRI-Determined Language Lateralization in Patients with Unilateral or Mixed Language Dominance According to the Wada Test , 2002, NeuroImage.

[33]  V. Schmithorst,et al.  Normal fMRI Brain Activation Patterns in Children Performing a Verb Generation Task , 2001, NeuroImage.

[34]  J. A. Frost,et al.  Determination of language dominance using functional MRI , 1996, Neurology.

[35]  G. McCarthy,et al.  Human Brain Mapping 6:1–13(1998) � Functional MRI Studies of Auditory Comprehension , 2022 .

[36]  J. A. Cameron,et al.  Presurgical evaluation of the motor hand area with functional MR imaging in patients with tumors and dysplastic lesions. , 1999, Radiology.

[37]  D Le Bihan,et al.  Functional MR evaluation of temporal and frontal language dominance compared with the Wada test , 2000, Neurology.

[38]  J. E Adcock,et al.  Quantitative fMRI assessment of the differences in lateralization of language-related brain activation in patients with temporal lobe epilepsy , 2003, NeuroImage.

[39]  A. Grinvald,et al.  Vascular imprints of neuronal activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Guillén Fernández,et al.  Language Mapping in Less Than 15 Minutes: Real-Time Functional MRI during Routine Clinical Investigation , 2001, NeuroImage.

[41]  N. F. Ramsey,et al.  Combined Analysis of Language Tasks in fMRI Improves Assessment of Hemispheric Dominance for Language Functions in Individual Subjects , 2001, NeuroImage.

[42]  M. D’Esposito,et al.  Functional MRI lateralization of memory in temporal lobe epilepsy , 1998, Neurology.

[43]  M Erb,et al.  Early left periventricular brain lesions induce right hemispheric organization of speech , 2001, Neurology.

[44]  J. Binder,et al.  Functional magnetic resonance imaging of human auditory cortex , 1994, Annals of neurology.

[45]  J. Pujol,et al.  Cerebral lateralization of language in normal left-handed people studied by functional MRI , 1999, Neurology.

[46]  R T Constable,et al.  Functional MRI of Language Processing: Dependence on Input Modality and Temporal Lobe Epilepsy , 2001, Epilepsia.

[47]  J. R. Baker,et al.  The hippocampal formation participates in novel picture encoding: evidence from functional magnetic resonance imaging. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[48]  S. Petersen,et al.  Hemispheric Specialization in Human Dorsal Frontal Cortex and Medial Temporal Lobe for Verbal and Nonverbal Memory Encoding , 1998, Neuron.

[49]  J. A. Frost,et al.  Somatotopic mapping of the human primary motor cortex with functional magnetic resonance imaging , 1995, Neurology.

[50]  T. L. Davis,et al.  Language dominance determined by whole brain functional MRI in patients with brain lesions , 1999, Neurology.

[51]  B. Tharp,et al.  Neonatal Seizures and Syndromes , 2002, Epilepsia.

[52]  D Le Bihan,et al.  Correspondence between functional magnetic resonance imaging somatotopy and individual brain anatomy of the central region: comparison with intraoperative stimulation in patients with brain tumors. , 2000, Journal of neurosurgery.

[53]  Byron Bernal,et al.  False lateralization of language cortex on functional MRI after a cluster of focal seizures. , 2002, Neurology.

[54]  W D Gaillard,et al.  fMRI identifies regional specialization of neural networks for reading in young children , 2003, Neurology.

[55]  M. Raichle,et al.  Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[56]  J W Belliveau,et al.  Location of language in the cortex: a comparison between functional MR imaging and electrocortical stimulation. , 1997, AJNR. American journal of neuroradiology.

[57]  G McCarthy,et al.  Comparative localization of auditory comprehension by using functional magnetic resonance imaging and cortical stimulation. , 1999, Journal of neurosurgery.

[58]  W. Gaillard,et al.  Auditory comprehension of language in young children , 2003, Neurology.

[59]  J. A. Frost,et al.  Language dominance in neurologically normal and epilepsy subjects , 1999 .

[60]  Peter T. Fox,et al.  Preoperative assessment of the cerebral hemispheric dominance for language with CBF PET , 1993 .

[61]  E. DeYoe,et al.  Functional magnetic resonance imaging (FMRI) of the human brain , 1994, Journal of Neuroscience Methods.

[62]  K Kuppusamy,et al.  Localization of language cortices by functional MR imaging compared with intracarotid amobarbital hemispheric sedation. , 1997, AJR. American journal of roentgenology.

[63]  V M Haughton,et al.  Functional magnetic resonance imaging of somatosensory stimulation. , 1994, Neurosurgery.

[64]  C B Dodrill,et al.  Brain injury, handedness, and speech lateralization in a series of amobarbital studies , 1988, Annals of neurology.

[65]  Judy Illes,et al.  Memory Lateralization in Medial Temporal Lobe Epilepsy Assessed by Functional MRI , 2002, Epilepsia.

[66]  E. T. Possing,et al.  Use of preoperative functional neuroimaging to predict language deficits from epilepsy surgery , 2003, Neurology.

[67]  S. Sato,et al.  fMRI language task panel improves determination of language dominance , 2004, Neurology.

[68]  J. Kassubek,et al.  Determination of hemisphere dominance for language: comparison of frontal and temporal fMRI activation with intracarotid amytal testing , 2002, Neuroradiology.

[69]  N. Logothetis The Underpinnings of the BOLD Functional Magnetic Resonance Imaging Signal , 2003, The Journal of Neuroscience.

[70]  R. Bakay,et al.  Functional magnetic resonance imaging localization of ictal onset to a dysplastic cleft with simultaneous sensorimotor mapping: intraoperative electrophysiological confirmation and postoperative follow-up: technical note. , 1998 .

[71]  E. Achten,et al.  Developing a comprehensive presurgical functional MRI protocol for patients with intractable temporal lobe epilepsy: a pilot study , 2002, Neuroradiology.

[72]  J. A. Frost,et al.  Side of seizure focus predicts left medial temporal lobe activation during verbal encoding , 1998, Neurology.

[73]  C. Sherrington,et al.  On the Regulation of the Blood‐supply of the Brain , 1890, The Journal of physiology.

[74]  R. Turner,et al.  Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[75]  J. Fell,et al.  Intrasubject reproducibility of presurgical language lateralization and mapping using fMRI , 2003, Neurology.

[76]  H. Noordmans,et al.  Development of a functional magnetic resonance imaging protocol for intraoperative localization of critical temporoparietal language areas , 2002, Annals of neurology.

[77]  F. Woermann,et al.  Language lateralization by Wada test and fMRI in 100 patients with epilepsy , 2003, Neurology.

[78]  Scott K Holland,et al.  Practical Aspects of Conducting Large-Scale Functional Magnetic Resonance Imaging Studies in Children , 2002, Journal of child neurology.

[79]  N F Ramsey,et al.  Language area localization with three‐dimensional functional magnetic resonance imaging matches intrasulcal electrostimulation in Broca's area , 1999, Annals of neurology.

[80]  P. Matthews,et al.  Defining a left-lateralized response specific to intelligible speech using fMRI. , 2003, Cerebral cortex.

[81]  N. F. Ramsey,et al.  Reproducibility of fMRI-Determined Language Lateralization in Individual Subjects , 2002, Brain and Language.

[82]  C. Jack,et al.  Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and invasive cortical mapping. , 1994, Radiology.

[83]  C. Weiller,et al.  Negative Dip in BOLD fMRI Is Caused by Blood Flow— Oxygen Consumption Uncoupling In Humans , 2002, NeuroImage.