The effect of CO2 laser excision on local tumor recurrence

This study was undertaken to determine the effect of CO2 laser surgery on the incidence of local recurrence following tumor recurrence and to study the effect of “sterilization” of the operative site on this phenomenon. Sixty Fisher 344 rats were implanted with R323OAC mammary carcinoma. Animals were anesthetized with intraperitoneal pentobarbital, and all tumors were completely excised at 21 days postimplantation.

[1]  T. Maiman.  Stimulated Optical Radiation in Ruby , 1960, Nature.

[2]  L. Goldman,et al.  Laser radiation of malignancy in man , 1965, Cancer.

[3]  N. Price,et al.  Treatment of basal-cell carcinomas with a carbon-dioxide laser. , 1979, The Journal of dermatologic surgery and oncology.

[4]  L. Gottlieb,et al.  Tumoricidal effect of laser energy on experimental and human malignant tumors. , 1965, The New England journal of medicine.

[5]  A. Ketcham,et al.  A surgeon's appraisal of the laser. , 1967, The Surgical clinics of North America.