Elevated levels of circulating adhesion molecules in patients with active pulmonary tuberculosis

Objective:  Recent studies have indicated the importance of cell adhesion molecules in the pathogenesis of various inflammatory lung diseases. Our study was designed to determine whether five soluble adhesion molecules including soluble L‐, E‐ and P‐selectin (sL‐, sE‐ and sP‐selectin), intercellular adhesion molecule‐1 (sICAM‐1), and vascular cell adhesion molecule‐1 (sVCAM‐1) in serum reflect the severity of active pulmonary tuberculosis (TB), and whether there is a distinct profile of these soluble molecules in this disease.

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