Automated neurite labeling and analysis in fluorescence microscopy images

To investigate the intricate nervous processes involved in many biological activities by computerized image analysis, accurate and reproducible labeling and measurement of neurites are prerequisite. We have developed an automated neurite analysis method to assist this task.

[1]  Alexei Degterev,et al.  Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury , 2005, Nature chemical biology.

[2]  Badrinath Roysam,et al.  Automated Three-Dimensional Tracing of Neurons in Confocal and Brightfield Images , 2003, Microscopy and Microanalysis.

[3]  Joakim Lindblad,et al.  Algorithms for Cytoplasm Segmentation of Fluorescence Labelled Cells , 2002, Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology.

[4]  John F. Canny,et al.  A Computational Approach to Edge Detection , 1986, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[5]  D. Agard Optical sectioning microscopy: cellular architecture in three dimensions. , 1984, Annual review of biophysics and bioengineering.

[6]  D. Agard,et al.  Fluorescence microscopy in three dimensions. , 1989, Methods in cell biology.

[7]  W. Brent Lindquist,et al.  Automated Algorithms for Multiscale Morphometry of Neuronal Dendrites , 2004, Neural Computation.

[8]  William H. Richardson,et al.  Bayesian-Based Iterative Method of Image Restoration , 1972 .

[9]  David F. Rogers,et al.  Procedural Elements for Computer Graphics , 1984 .

[10]  Khalid A. Al-Kofahi,et al.  Median-based robust algorithms for tracing neurons from noisy confocal microscope images , 2003, IEEE Transactions on Information Technology in Biomedicine.

[11]  L. Lucy An iterative technique for the rectification of observed distributions , 1974 .

[12]  W. Brent Lindquist,et al.  An Image Analysis Algorithm for Dendritic Spines , 2002, Neural Computation.

[13]  T. Mitchison,et al.  Phenotypic screening of small molecule libraries by high throughput cell imaging. , 2003, Combinatorial chemistry & high throughput screening.

[14]  Khalid A. Al-Kofahi,et al.  Rapid automated three-dimensional tracing of neurons from confocal image stacks , 2002, IEEE Transactions on Information Technology in Biomedicine.

[15]  Lani F. Wu,et al.  Multidimensional Drug Profiling By Automated Microscopy , 2004, Science.

[16]  Andrew R. Cohen,et al.  Automated tracing and volume measurements of neurons from 3‐D confocal fluorescence microscopy data , 1994, Journal of microscopy.

[17]  Ki-Sang Hong,et al.  Detection of curvilinear structures and reconstruction of their regions in gray-scale images , 2002, Pattern Recognit..

[18]  Tony Lindeberg,et al.  Feature Detection with Automatic Scale Selection , 1998, International Journal of Computer Vision.

[19]  Carsten Steger,et al.  An Unbiased Detector of Curvilinear Structures , 1998, IEEE Trans. Pattern Anal. Mach. Intell..

[20]  Xiaobo Zhou,et al.  Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy , 2006, IEEE Transactions on Biomedical Engineering.

[21]  Luis Ibáñez,et al.  The ITK Software Guide , 2005 .

[22]  E Meijering,et al.  Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images , 2004, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[23]  Donald Ervin Knuth,et al.  The Art of Computer Programming , 1968 .

[24]  Xiaobo Zhou,et al.  A computerized cellular imaging system for high content analysis in Monastrol suppressor screens , 2006, J. Biomed. Informatics.

[25]  David H. Eberly,et al.  Ridges for image analysis , 1994, Journal of Mathematical Imaging and Vision.