Embedded radiometry system for biomedical applications via thermal diffusivity properties

A Radiometry Photothermal Infrared technique, by using a calibrated scanning depth profile, for biomedical applications is described. The instrument, consists of a pulsed medium-power laser (500 mw), collected and focused onto an infrared detector after impinging on the sample, by using a look-in amplifier, thereby obtaining the amplitude and phase of the modulated signal, collected by an embedded system. The system was tested by using Ag nanoparticles (average diameter 10 to 30 nm), obtained by chemical reduction of AgNO3, at concentrations of 1, 0.5, 0.25, 0.125 and 0.062 % in water.

[1]  Dong Rip Kim,et al.  Enhancement of photo-thermal conversion using gold nanofluids with different particle sizes , 2016 .

[2]  Bastien Arnal,et al.  Sono-photoacoustic imaging of gold nanoemulsions: Part II. Real time imaging , 2015, Photoacoustics.

[3]  S. Emelianov,et al.  Visualization of molecular composition and functionality of cancer cells using nanoparticle-augmented ultrasound-guided photoacoustics , 2015, Photoacoustics.

[4]  M. O’Donnell,et al.  Sono-photoacoustic imaging of gold nanoemulsions: Part I. Exposure thresholds , 2015, Photoacoustics.

[5]  Yijian Zeng,et al.  An improved two-layer algorithm for estimating effective soil temperature in microwave radiometry using in situ temperature and soil moisture measurements , 2014 .

[6]  M. Malinski,et al.  Noncontact measurement of the thermal diffusivity of IR semi-transparent and semiconducting n-CdMgSe mixed crystals by means of the photothermal radiometry , 2014 .

[7]  Ian Sorrell,et al.  Combined mathematical modelling and experimentation to predict polymersome uptake by oral cancer cells. , 2014, Nanomedicine : nanotechnology, biology, and medicine.

[8]  S. Emelianov,et al.  Contrast-enhanced magneto-photo-acoustic imaging in vivo using dual-contrast nanoparticles☆ , 2014, Photoacoustics.

[9]  Emmanuel Bossy,et al.  Influence of nanoscale temperature rises on photoacoustic generation: Discrimination between optical absorbers based on thermal nonlinearity at high frequency , 2013, Photoacoustics.

[10]  J. Battaglia,et al.  Using pulsed and modulated photothermal radiometry to measure the thermal conductivity of thin films , 2013 .

[11]  Zhuomin M. Zhang.  Radiometric temperature measurements, vol. 1 , 2010 .