Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats.

[1]  G. Casadesus,et al.  Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. , 2013, Current Alzheimer research.

[2]  Xiangdong Gao,et al.  Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer’s disease by exendin-4 , 2012, AGE.

[3]  N. Starkova,et al.  Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  M. Dragunow,et al.  Epigenetics in Alzheimer's disease: a focus on DNA modifications. , 2011, Current pharmaceutical design.

[5]  M. Shigemori,et al.  Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction. , 2011, Experimental and therapeutic medicine.

[6]  Q. Li,et al.  Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating the redox status and up-regulating the plasticity-related proteins in hippocampus , 2011, Neuroscience.

[7]  P. Riederer,et al.  Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer’s disease: a long-term follow up study , 2011, Journal of Neural Transmission.

[8]  S. Scheff,et al.  Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex , 2010, Journal of neuropathology and experimental neurology.

[9]  M. Mattson Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders , 2009, Experimental Gerontology.

[10]  T. Ishrat,et al.  Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT) , 2009, European Neuropsychopharmacology.

[11]  Kehkashan Parveen,et al.  Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type , 2009, Brain Research.

[12]  N. Zawia,et al.  Epigenetics, oxidative stress, and Alzheimer disease. , 2009, Free radical biology & medicine.

[13]  W. Noble,et al.  Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. , 2009, Trends in molecular medicine.

[14]  Paolo Zamboni,et al.  Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options , 2009, Current neuropharmacology.

[15]  E. Ling,et al.  Antioxidants and neuroprotection in the adult and developing central nervous system. , 2008, Current medicinal chemistry.

[16]  G. Perry,et al.  Oxidative stress signaling in Alzheimer's disease. , 2008, Current Alzheimer research.

[17]  S. Nakano,et al.  Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice , 2008, Experimental Neurology.

[18]  Q. Tian,et al.  Inhibition of protein phosphatases induces transport deficits and axonopathy , 2007, Journal of neurochemistry.

[19]  C. Masters,et al.  Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau , 2007, PloS one.

[20]  L. Mucke,et al.  Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model , 2007, Science.

[21]  P. Riederer,et al.  Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein , 2007, Journal of neurochemistry.

[22]  Jian-Zhi Wang,et al.  Effects of tau phosphorylation on proteasome activity , 2007, FEBS letters.

[23]  M. Beal,et al.  Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases , 2006, Nature.

[24]  Y. Namiki,et al.  Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. , 2006, CNS drug reviews.

[25]  Ning Zhang,et al.  Edaravone Reduces Early Accumulation of Oxidative Products and Sequential Inflammatory Responses After Transient Focal Ischemia in Mice Brain , 2005, Stroke.

[26]  G. Perry,et al.  Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. , 2005, Free radical biology & medicine.

[27]  Colin L. Masters,et al.  Neurodegenerative diseases and oxidative stress , 2004, Nature Reviews Drug Discovery.

[28]  Mark P Mattson,et al.  Metal‐Catalyzed Disruption of Membrane Protein and Lipid Signaling in the Pathogenesis of Neurodegenerative Disorders , 2004, Annals of the New York Academy of Sciences.

[29]  M. Mattson,et al.  Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Y. Itoyama,et al.  MCI-186 prevents spinal cord damage and affects enzyme levels of nitric oxide synthase and Cu/Zn superoxide dismutase after transient ischemia in rabbits. , 2003, The Journal of thoracic and cardiovascular surgery.

[31]  Guoyao Wu,et al.  Free radicals, antioxidants, and nutrition. , 2002, Nutrition.

[32]  R. Adolphs Neural systems for recognizing emotion , 2002, Current Opinion in Neurobiology.

[33]  LJ Forman,et al.  Free radical oxidative damage and Alzheimer's disease , 2001, The Journal of the American Osteopathic Association.

[34]  T. Arendt Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization , 2001, Neuroscience.

[35]  Y. Gupta,et al.  Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. , 2001, Life sciences.

[36]  R. Tabrizchi Edaravone Mitsubishi-Tokyo. , 2000, Current opinion in investigational drugs.

[37]  D. Praticò,et al.  Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. , 2000, The American journal of medicine.

[38]  J. Hirrlinger,et al.  Glutathione metabolism in brain , 2000 .

[39]  Y. Christen,et al.  Oxidative stress and Alzheimer disease. , 2000, The American journal of clinical nutrition.

[40]  W. Markesbery The role of oxidative stress in Alzheimer disease. , 1999, Archives of neurology.

[41]  W. Markesbery,et al.  Protein Oxidation in Aging Brain a , 1992, Annals of the New York Academy of Sciences.

[42]  Bradley T. Hyman,et al.  Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease , 1992, Neurology.

[43]  C. Babbs,et al.  Quantitation of the hydroxyl radical by reaction with dimethyl sulfoxide. , 1990, Archives of biochemistry and biophysics.

[44]  R. Morris Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.

[45]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[46]  M. Baudry,et al.  Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline. , 2012, Journal of Alzheimer's Disease.

[47]  Takashi Ito,et al.  Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review). , 2012, Experimental and therapeutic medicine.

[48]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[49]  George Perry,et al.  Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. , 2010, Journal of Alzheimer's disease : JAD.

[50]  S. Hoyer,et al.  Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach. , 2007, Journal of neural transmission. Supplementum.

[51]  J. Hirrlinger,et al.  Peroxide detoxification by brain cells , 2005, Journal of neuroscience research.

[52]  J. Sedlák,et al.  Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. , 1968, Analytical biochemistry.