Serum lipoprotein concentrations in a schizophrenic population.

fects or whether this was a statistical accident cannot be determined on the basis of the relatively small number of cases. Certainly this mepazine-chlorpromazine combination was the most effective one in both the males and females. The expectation of finding a single ataractic agent that would be effective for all types of patients has not and is not likely to be realized. Rather we are having made available to us a sizeable number of pharmaceuticals which can be used selectively to meet the needs of the individual patient. On the basis of our experience with mepazine, not only in the hospital, but in private practice, and through information provided both in the literature and in conversation with numerous practicing psychiatrists, certain tentative conclusions can be drawn as to its use: i. Of the ataractic agents presently available mepazine apparently induces the least depression and may even serve to relieve mild depressions when they pre-exist. 2. The incidence of blood dyscrasias in the females suggests that mepazine (along with the other phenothiazine derivatives) be used with considerable caution and under close medical supervision for the first month and a half. Patients should be told to report immediately any evidence of temperature elevation and “scratchy” or sore throat since these clinical symptoms usually appear early enough to prevent a serious blood dyscrasia by withdrawing medication. This limitation is set since no record of a blood dyscrasia occurring beyond the 45th day has been reported.