Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment

[1]  P. Demant,et al.  Cancer susceptibility in the mouse: genetics, biology and implications for human cancer , 2003, Nature Reviews Genetics.

[2]  Mary Helen Barcellos-Hoff,et al.  Radiation and the microenvironment – tumorigenesis and therapy , 2005, Nature Reviews Cancer.

[3]  M. Barcellos-Hoff.  TGFβ Biology in Breast: 15 Years On , 2011, Journal of Mammary Gland Biology and Neoplasia.

[4]  M. Barcellos-Hoff,et al.  Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. , 2000, Cancer research.

[5]  Allan Balmain,et al.  Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene , 2004, Nature.

[6]  Allan Balmain,et al.  TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice , 1996, Cell.

[7]  S. Naber,et al.  BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice. , 2003, Cancer research.

[8]  Keiji Suzuki,et al.  Low-dose radiation exposure and carcinogenesis. , 2012, Japanese journal of clinical oncology.

[9]  R. Okayasu,et al.  A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse. , 2000, Cancer research.

[10]  Daniel A Fletcher,et al.  Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures , 2006, Science.

[11]  F. Kittrell,et al.  Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome. , 2000, The American journal of pathology.

[12]  J. Mao,et al.  Cancer evolution and individual susceptibility. , 2011, Integrative biology : quantitative biosciences from nano to macro.

[13]  E. Tzehoval,et al.  Role of cytokines in termination of the B cell lymphoma dormant state in AKR mice. , 1995, Leukemia.

[14]  William C Hines,et al.  Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression , 2011, Nature Medicine.

[15]  Z. Werb,et al.  Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.

[16]  P. Nguyen,et al.  Radiation exposure from imaging tests: is there an increased cancer risk? , 2011, Expert review of cardiovascular therapy.

[17]  M. Komínková.  [15 years]. , 1975, Zdravotnicka pracovnice.

[18]  L. Wakefield,et al.  TGF-beta signaling: positive and negative effects on tumorigenesis. , 2002, Current opinion in genetics & development.

[19]  D. Krewski,et al.  Database of Radiogenic Cancer in Experimental Animals Exposed to Low Doses of Ionizing Radiation , 2012, Journal of toxicology and environmental health. Part B, Critical reviews.

[20]  M. Sporn,et al.  Transforming growth factor-beta and suppression of carcinogenesis. , 1989, Princess Takamatsu symposia.

[21]  E. Wright,et al.  Responses to ionizing radiation mediated by inflammatory mechanisms , 2014, The Journal of pathology.

[22]  M. Sporn,et al.  Transforming growth factor-beta s in mammary tumorigenesis: promoters or antipromoters? , 1995, Progress in clinical and biological research.

[23]  L. Wakefield,et al.  The two faces of transforming growth factor beta in carcinogenesis. , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Mina J. Bissell,et al.  Putting tumours in context , 2001, Nature Reviews Cancer.

[25]  G. Cunha,et al.  Stromal regulation of epithelial function. , 1991, Cancer treatment and research.

[26]  A. Balmain,et al.  Genomic approaches to identification of tumour-susceptibility genes using mouse models. , 2003, Current opinion in genetics & development.

[27]  M. Bissell,et al.  Constructing Three-Dimensional Models to Study Mammary Gland Branching Morphogenesis and Functional Differentiation , 2012, Journal of Mammary Gland Biology and Neoplasia.

[28]  Andrew Burgess,et al.  Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance , 2010, Proceedings of the National Academy of Sciences.

[29]  L. Wakefield,et al.  The two faces of transforming growth factor β in carcinogenesis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[30]  M. Barcellos-Hoff,et al.  TGF-beta biology in mammary development and breast cancer. , 2011, Cold Spring Harbor perspectives in biology.

[31]  Jiri Zavadil,et al.  Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. , 2011, Cancer cell.

[32]  Simon Bouffler,et al.  Assessing cancer risks of low-dose radiation , 2009, Nature Reviews Cancer.

[33]  A. Balmain,et al.  A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice , 2006, Nature Genetics.

[34]  Bahram Parvin,et al.  Targeted and nontargeted effects of ionizing radiation that impact genomic instability. , 2008, Cancer research.

[35]  Hiroki Nagase,et al.  Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human , 2003, Nature Genetics.

[36]  T. Lapidot,et al.  Increased circulating colony-stimulating factor-1 (CSF-1) in SJL/J mice with radiation-induced acute myeloid leukemia (AML) is associated with autocrine regulation of AML cells by CSF-1. , 1997, Blood.

[37]  M. Doublet-Stewart,et al.  Controversy continues , 1988, Nature.

[38]  B. Tartakovsky,et al.  Low doses of radiation induce systemic production of cytokines: Possible contribution to leukemogenesis , 1993, International journal of cancer.

[39]  L. Wakefield,et al.  TGF-β signaling: positive and negative effects on tumorigenesis , 2002 .

[40]  W. J. Bair,et al.  Issues in Low Dose Radiation Biology: The Controversy Continues. A Perspective , 2013, Radiation research.

[41]  Enrique Egaña,et al.  Effects of Ionizing Radiation , 1971 .