Solitary Intramedullary Spinal Cord Metastasis from Colon Carcinoma: A Case Report and Literature Review

It is extremely rare for cancer to present as an intramedullary spinal cord metastasis. The authors report on a case of a 74-year-old woman presenting with progressive tetraparesis to metastatic colon adenocarcinoma in the spinal cord. A review of the literature reveals that intramedullary localization is associated with a very short life expectancy, with a median survival of 3-4 months from the time of the diagnosis; nevertheless microsurgical removal of tumor can improve quality of life.

[1]  R. Gupta,et al.  Intramedullary spinal cord metastasis from colonic carcinoma presenting as Brown-Séquard syndrome: a case report , 2011, Journal of medical case reports.

[2]  A. Florena,et al.  Intramedullary spinal cord tumor presenting as the initial manifestation of metastatic colon cancer: case report and review of the literature , 2007, Spinal Cord.

[3]  Sung-Bae Kim,et al.  Intramedullary spinal cord metastases: a single-institution experience , 2007, Journal of Neuro-Oncology.

[4]  D. Schiff,et al.  Metastasis to nervous system: spinal epidural and intramedullary metastases , 2005, Journal of Neuro-Oncology.

[5]  T. Gasser,et al.  Surgical treatment of intramedullary spinal cord metastases of systemic cancer: functional outcome and prognosis , 2005, Journal of Neuro-Oncology.

[6]  T. Dalkılıç,et al.  Intramedullary spinal cord metastasis: a rare and devastating complication of cancer--two case reports. , 2003, Neurologia medico-chirurgica.

[7]  M. Ogino,et al.  Successful removal of solitary intramedullary spinal cord metastasis from colon cancer , 2002, Clinical Neurology and Neurosurgery.

[8]  Y. Iwasaki,et al.  [Intramedullary spinal cord metastasis: two case reports and literature review]. , 2002, No shinkei geka. Neurological surgery.

[9]  E. Connolly,et al.  Intramedullary spinal cord metastasis: report of three cases and review of the literature. , 1996, Surgical neurology.

[10]  B. O'neill,et al.  Intramedullary spinal cord metastases , 1996, Neurology.

[11]  G. Lanzino,et al.  Metastases of the spinal cord from remote neoplasms. Study of five cases. , 1988, Surgical neurology.

[12]  H. Crockard,et al.  Syrinx associated with intramedullary metastasis. , 1987, Journal of neurology, neurosurgery, and psychiatry.

[13]  D. Adelstein,et al.  Intramedullary spinal cord metastasis. Diagnostic and therapeutic considerations. , 1987, Archives of neurology.

[14]  J. Dunne,et al.  Intramedullary spinal cord metastases: a clinical and pathological study of nine cases. , 1986, The Quarterly journal of medicine.

[15]  J. Grem,et al.  Clinical features and natural history of intramedullary spinal cord metastasis , 1985, Cancer.

[16]  M. Winkelman,et al.  Intramedullary spinal cord metastasis. A clinicopathological study of 13 cases. , 1985, Journal of neurosurgery.

[17]  G. Fumagalli,et al.  Intramedullary spinal cord metastases. , 1983, Journal of neurosurgical sciences.

[18]  J. Posner,et al.  Intramedullary spinal cord metastases , 1972, Neurology.

[19]  B. Mcswain,et al.  Intramedullary spinal cord metastasis: the sole clinical manifestation of an adenocarcinoma of the colon. , 1967, Canadian journal of surgery. Journal canadien de chirurgie.

[20]  Walker Lg.  Intramedullary spinal cord metastasis from carcinoma of the colon. , 1967 .

[21]  J. Chason,et al.  Metastatic carcinoma in the central nervous system and dorsal root ganglia. A prospective autopsy study , 1963, Cancer.

[22]  Sansoy Om.  Intramedullary spinal cord metastasis from carcinoma of the colon simulating acute ascending myelitis. , 1955 .

[23]  J. M. Stein,et al.  INTRAMEDULLARY SPINAL CORD METASTASIS* , 1952, The Journal of nervous and mental disease.