A computational model of reactive oxygen species and redox balance in cardiac mitochondria.
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[1] Mark Friedman,et al. Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis , 2012, PLoS Comput. Biol..
[2] Brian O'Rourke,et al. Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: An experimental-computational study , 2012, The Journal of general physiology.
[3] R. Springett,et al. Measurement of the mitochondrial membrane potential and pH gradient from the redox poise of the hemes of the bc1 complex. , 2012, Biophysical journal.
[4] U. Brandt. A two-state stabilization-change mechanism for proton-pumping complex I. , 2011, Biochimica et biophysica acta.
[5] S. Vogt,et al. The role of mitochondrial membrane potential in ischemic heart failure. , 2011, Mitochondrion.
[6] R. Efremov,et al. Structure of the membrane domain of respiratory complex I , 2011, Nature.
[7] N. Larsson,et al. Tracing the Trail of Protons through Complex I of the Mitochondrial Respiratory Chain , 2011, PLoS biology.
[8] R. Winslow,et al. Mitochondrial energetics, pH regulation, and ion dynamics: a computational-experimental approach. , 2011, Biophysical journal.
[9] J. Hirst,et al. Superoxide Is Produced by the Reduced Flavin in Mitochondrial Complex I , 2011, The Journal of Biological Chemistry.
[10] Josep Roca,et al. Reactive Oxygen Species Production by Forward and Reverse Electron Fluxes in the Mitochondrial Respiratory Chain , 2011, PLoS Comput. Biol..
[11] K. Krab,et al. Explaining the enigmatic K(M) for oxygen in cytochrome c oxidase: a kinetic model. , 2011, Biochimica et biophysica acta.
[12] Daniel A Beard,et al. Kinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I). , 2010, Biophysical journal.
[13] S. Cortassa,et al. Redox-optimized ROS balance: a unifying hypothesis. , 2010, Biochimica et biophysica acta.
[14] B. O’Rourke,et al. Elevated Cytosolic Na+ Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes , 2010, Circulation.
[15] Josep Roca,et al. Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia , 2009, PLoS Comput. Biol..
[16] F. Zoccarato,et al. Succinate is the controller of O2−/H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide , 2009, Journal of bioenergetics and biomembranes.
[17] R. Winslow,et al. Modeling cardiac action potential shortening driven by oxidative stress-induced mitochondrial oscillations in guinea pig cardiomyocytes. , 2009, Biophysical journal.
[18] Feng Qi,et al. Generating rate equations for complex enzyme systems by a computer-assisted systematic method , 2009, BMC Bioinformatics.
[19] B. Trumpower,et al. Membrane Potential Greatly Enhances Superoxide Generation by the Cytochrome bc1 Complex Reconstituted into Phospholipid Vesicles* , 2009, The Journal of Biological Chemistry.
[20] Fuhua Chen,et al. Oxidative Stress–Induced Afterdepolarizations and Calmodulin Kinase II Signaling , 2008, Circulation research.
[21] M. Sarewicz,et al. Movement of the iron-sulfur head domain of cytochrome bc(1) transiently opens the catalytic Q(o) site for reaction with oxygen. , 2008, Biochemistry.
[22] Sarah E. Chobot,et al. Quinone and non-quinone redox couples in Complex III , 2008, Journal of bioenergetics and biomembranes.
[23] Josep Roca,et al. The Role of External and Matrix pH in Mitochondrial Reactive Oxygen Species Generation* , 2008, Journal of Biological Chemistry.
[24] B. O’Rourke,et al. Enhancing Mitochondrial Ca2+ Uptake in Myocytes From Failing Hearts Restores Energy Supply and Demand Matching , 2008, Circulation research.
[25] U. Brandt,et al. The Mechanism of Mitochondrial Superoxide Production by the Cytochrome bc1 Complex* , 2008, Journal of Biological Chemistry.
[26] P. Dutton,et al. Exposing the complex III Qo semiquinone radical. , 2007, Biochimica et biophysica acta.
[27] David M Kramer,et al. A semiquinone intermediate generated at the Qo site of the cytochrome bc1 complex: Importance for the Q-cycle and superoxide production , 2007, Proceedings of the National Academy of Sciences.
[28] M. L. Genova,et al. Kinetics of integrated electron transfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling. , 2007, American journal of physiology. Cell physiology.
[29] T. Billiar,et al. Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[30] C. Chinopoulos,et al. Bioenergetics and the formation of mitochondrial reactive oxygen species. , 2006, Trends in pharmacological sciences.
[31] John E. Walker,et al. Bovine Complex I Is a Complex of 45 Different Subunits* , 2006, Journal of Biological Chemistry.
[32] Tammer A. Farid,et al. Electron tunneling chains of mitochondria. , 2006, Biochimica et biophysica acta.
[33] Raimond L Winslow,et al. A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte. , 2006, Biophysical journal.
[34] Min Zhang,et al. NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure. , 2006, Cardiovascular research.
[35] J. Hirst,et al. The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[36] A. Vinogradov,et al. Generation of superoxide by the mitochondrial Complex I. , 2006, Biochimica et biophysica acta.
[37] P. Schumacker,et al. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. , 2005, Cell metabolism.
[38] Frank J Giordano,et al. Oxygen, oxidative stress, hypoxia, and heart failure. , 2005, The Journal of clinical investigation.
[39] F. Muller,et al. Complex III Releases Superoxide to Both Sides of the Inner Mitochondrial Membrane* , 2004, Journal of Biological Chemistry.
[40] A. J. Lambert,et al. Inhibitors of the Quinone-binding Site Allow Rapid Superoxide Production from Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I)* , 2004, Journal of Biological Chemistry.
[41] A. J. Lambert,et al. Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane. , 2004, The Biochemical journal.
[42] Raimond L Winslow,et al. A mitochondrial oscillator dependent on reactive oxygen species. , 2004, Biophysical journal.
[43] J. Turrens,et al. Mitochondrial formation of reactive oxygen species , 2003, The Journal of physiology.
[44] Bernhard Kadenbach,et al. Intrinsic and extrinsic uncoupling of oxidative phosphorylation. , 2003, Biochimica et biophysica acta.
[45] R. Winslow,et al. An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. , 2003, Biophysical journal.
[46] E. Cadenas,et al. Voltage-dependent Anion Channels Control the Release of the Superoxide Anion from Mitochondria to Cytosol* , 2003, The Journal of Biological Chemistry.
[47] A. Murphy,et al. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. , 2002, The Biochemical journal.
[48] M. Brand,et al. Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain* , 2002, The Journal of Biological Chemistry.
[49] Q. Jin,et al. Kinetics of electron transfer through the respiratory chain. , 2002, Biophysical journal.
[50] A. Takeshita,et al. Probucol Attenuates Left Ventricular Dysfunction and Remodeling in Tachycardia-Induced Heart Failure: Roles of Oxidative Stress and Inflammation , 2002, Circulation.
[51] B. Kholodenko,et al. Kinetic Modeling of Energy Metabolism and Superoxide Generation in Hepatocyte Mitochondria , 2001, Molecular Biology.
[52] M. L. Genova,et al. The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2 , 2001, FEBS letters.
[53] Freya Q. Schafer,et al. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. , 2001, Free radical biology & medicine.
[54] G. Fiskum,et al. Myxothiazol Induces H2O2 Production from Mitochondrial Respiratory Chain , 2001 .
[55] A. Takeshita,et al. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. , 1999, Circulation research.
[56] Shu-sen Liu,et al. Cooperation of a “Reactive Oxygen Cycle” with The Q Cycle and The Proton Cycle in the Respiratory Chain—Superoxide Generating and Cycling Mechanisms in Mitochondria , 1999, Journal of bioenergetics and biomembranes.
[57] B. Kholodenko,et al. A model of O·2-generation in the complex III of the electron transport chain , 1998 .
[58] P. Brzezinski,et al. Pathways of Proton Transfer in Cytochrome c Oxidase , 1998, Journal of bioenergetics and biomembranes.
[59] V. Skulachev,et al. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria , 1997, FEBS letters.
[60] J. Keizer,et al. Minimal model of beta-cell mitochondrial Ca2+ handling. , 1997, The American journal of physiology.
[61] Y. Orii,et al. Oxidation Process of Bovine Heart Ubiquinol-Cytochrome c Reductase as Studied by Stopped-flow Rapid-scan Spectrophotometry and Simulations Based on the Mechanistic Q Cycle Model* , 1997, The Journal of Biological Chemistry.
[62] M. Brand,et al. Relationship between membrane potential and respiration rate in isolated liver mitochondria from rats fed an energy dense diet , 1996, Molecular and Cellular Biochemistry.
[63] G. Radda,et al. Insulin, ketone bodies, and mitochondrial energy transduction , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[64] Y. Hatefi,et al. Thermodynamic analysis of flavin in mitochondrial NADH:ubiquinone oxidoreductase (complex I). , 1994, Biochemistry.
[65] L. Scorrano,et al. The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents. , 1994, The Journal of biological chemistry.
[66] G. Gores,et al. Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. , 1993, The American journal of physiology.
[67] T. Ohnishi,et al. Determination of the position of the Qi.- quinone binding site from the protein surface of the cytochrome bc1 complex in Rhodobacter capsulates chromatophores. , 1992, Biochimica et biophysica acta.
[68] W. Cramer,et al. Energy Transduction in Biological Membranes , 1991 .
[69] G. Brown,et al. Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. , 1990, European journal of biochemistry.
[70] A. Lehninger,et al. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. , 1985, Archives of biochemistry and biophysics.
[71] G. Brown,et al. Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex. , 1985, The Biochemical journal.
[72] J. Turrens,et al. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. , 1980, The Biochemical journal.
[73] E. Cadenas,et al. Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria. , 1980, The Biochemical journal.
[74] E. Robin,et al. Redox state of free nicotinamide-adenine nucleotides in the cytoplasm and mitochondria of alveolar macrophages. , 1971, The Journal of clinical investigation.
[75] E. C. Slater,et al. The redox states of respiratory-chain components in rat-liver mitochondria. II. The "crossover" on the transition from state 3 to state 4. , 1969, Biochimica et biophysica acta.
[76] U. Brandt,et al. Molecular mechanisms of superoxide production by the mitochondrial respiratory chain. , 2012, Advances in experimental medicine and biology.
[77] David F Wilson,et al. Regulation of cellular energy metabolism , 2005, The Journal of Membrane Biology.
[78] B. Kholodenko,et al. A model of O·2- generation in the complex III of the electron transport chain , 2004, Molecular and Cellular Biochemistry.
[79] W. Dröge. Free radicals in the physiological control of cell function. , 2002, Physiological reviews.
[80] G. Fiskum,et al. Myxothiazol induces H(2)O(2) production from mitochondrial respiratory chain. , 2001, Biochemical and biophysical research communications.
[81] B. Kholodenko,et al. Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding. , 2000, The Biochemical journal.
[82] B. Kholodenko,et al. A model of O2.-generation in the complex III of the electron transport chain. , 1998, Molecular and cellular biochemistry.
[83] J. Downey,et al. Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium. , 1997, Journal of molecular and cellular cardiology.
[84] W. Cramer,et al. Energy transduction in biological membranes : a textbook of bioenergetics , 1991 .
[85] E. Reid. CHAPTER 5 – Carbohydrate and Fatty Acid Metabolism , 1965 .