Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.

[1]  I. Cheeseman,et al.  The molecular basis for centromere identity and function , 2015, Nature Reviews Molecular Cell Biology.

[2]  Andreas Ritter,et al.  Manipulating The Mouse Embryo A Laboratory Manual , 2016 .

[3]  Robert G. Parton,et al.  Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis , 2016, Nature.

[4]  G. Dressler,et al.  Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms. , 2015, Developmental biology.

[5]  B. Brenner,et al.  Birth weight, malnutrition and kidney-associated outcomes—a global concern , 2015, Nature Reviews Nephrology.

[6]  G. Dressler,et al.  The Groucho-associated Phosphatase PPM1B Displaces Pax Transactivation Domain Interacting Protein (PTIP) to Switch the Transcription Factor Pax2 from a Transcriptional Activator to a Repressor* , 2015, The Journal of Biological Chemistry.

[7]  M. Bouchard,et al.  Coordinated cell behaviours in early urogenital system morphogenesis. , 2014, Seminars in cell & developmental biology.

[8]  A. McMahon,et al.  Induction and patterning of the metanephric nephron. , 2014, Seminars in cell & developmental biology.

[9]  D. Herzlinger,et al.  Patterning the renal vascular bed. , 2014, Seminars in cell & developmental biology.

[10]  Jianbo Sun,et al.  Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis. , 2014, Developmental cell.

[11]  A. McMahon,et al.  Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis , 2014, Stem cell reports.

[12]  S. Potter,et al.  Single cell dissection of early kidney development: multilineage priming , 2014, Development.

[13]  M. Nakao,et al.  Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor. , 2014, Journal of the American Society of Nephrology : JASN.

[14]  Gernot Neumayer,et al.  TPX2: of spindle assembly, DNA damage response, and cancer , 2014, Cellular and Molecular Life Sciences.

[15]  R. A. Gomez,et al.  RBP-J in FOXD1+ renal stromal progenitors is crucial for the proper development and assembly of the kidney vasculature and glomerular mesangial cells. , 2014, American journal of physiology. Renal physiology.

[16]  Zhenyi Liu,et al.  Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development , 2014, Development.

[17]  R. Nishinakamura,et al.  Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. , 2014, Cell stem cell.

[18]  R. Iozzo,et al.  FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney , 2014, Development.

[19]  G. Egan,et al.  Why and how we determine nephron number , 2014, Pediatric Nephrology.

[20]  M. Takasato,et al.  Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors. , 2013, Journal of the American Society of Nephrology : JASN.

[21]  S. Glenn,et al.  Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease. , 2013, The American journal of pathology.

[22]  J. Skotheim,et al.  Control of cell cycle transcription during G1 and S phases , 2013, Nature Reviews Molecular Cell Biology.

[23]  R. Kalluri,et al.  Origin and function of myofibroblasts in kidney fibrosis , 2013, Nature Medicine.

[24]  G. Remuzzi,et al.  Renal progenitors: an evolutionary conserved strategy for kidney regeneration , 2013, Nature Reviews Nephrology.

[25]  Jie Wu,et al.  TopCluster: A hybrid cluster model to support dynamic deployment in Grid , 2013, J. Comput. Syst. Sci..

[26]  Hollis G. Potter,et al.  Author Manuscript , 2013 .

[27]  T. Kapoor,et al.  Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore , 2012, Nature Reviews Molecular Cell Biology.

[28]  Stephen S. Taylor,et al.  The Spindle Assembly Checkpoint , 2012, Current Biology.

[29]  Wing Hong Wong,et al.  Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. , 2012, Developmental cell.

[30]  F. Costantini Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system , 2012, Wiley interdisciplinary reviews. Developmental biology.

[31]  T. Hirano Condensins: universal organizers of chromosomes with diverse functions. , 2012, Genes & development.

[32]  R. Salomon,et al.  FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man. , 2012, Developmental cell.

[33]  A. McMahon,et al.  Mammalian kidney development: principles, progress, and projections. , 2012, Cold Spring Harbor perspectives in biology.

[34]  R. A. Gomez,et al.  Development of the renal arterioles. , 2011, Journal of the American Society of Nephrology : JASN.

[35]  S. Potter,et al.  Defining the Molecular Character of the Developing and Adult Kidney Podocyte , 2011, PloS one.

[36]  R. Baldock,et al.  The GUDMAP database – an online resource for genitourinary research , 2011, Development.

[37]  L. Lum,et al.  Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development , 2011, Development.

[38]  J. C. Belmonte,et al.  Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration , 2011, Nature Reviews Molecular Cell Biology.

[39]  M. Little,et al.  Defining and redefining the nephron progenitor population , 2011, Pediatric Nephrology.

[40]  G. Dressler Patterning and early cell lineage decisions in the developing kidney: the role of Pax genes , 2011, Pediatric Nephrology.

[41]  A. Reymond,et al.  A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo , 2011, PLoS biology.

[42]  Alexander R. Pico,et al.  Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation , 2010, Proceedings of the National Academy of Sciences.

[43]  F. Costantini,et al.  Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. , 2010, Developmental cell.

[44]  A. McMahon,et al.  Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. , 2010, The American journal of pathology.

[45]  W. Earnshaw,et al.  Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins , 2009, Current opinion in cell biology.

[46]  Leif Oxburgh,et al.  BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism , 2009, Development.

[47]  N. Hirokawa,et al.  Kinesin superfamily motor proteins and intracellular transport , 2009, Nature Reviews Molecular Cell Biology.

[48]  A. Means,et al.  Faculty Opinions recommendation of The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. , 2009 .

[49]  O. Madsen,et al.  The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells , 2009, Cell.

[50]  Jing Chen,et al.  ToppGene Suite for gene list enrichment analysis and candidate gene prioritization , 2009, Nucleic Acids Res..

[51]  M. Couillard,et al.  C‐myc as a modulator of renal stem/progenitor cell population , 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

[52]  A. McMahon,et al.  Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. , 2008, Developmental biology.

[53]  Aaron Schindeler,et al.  Seminars in cell & developmental biology. , 2008, Seminars in cell & developmental biology.

[54]  A. McMahon,et al.  Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. , 2008, Cell stem cell.

[55]  A. McMahon,et al.  Intrinsic epithelial cells repair the kidney after injury. , 2008, Cell stem cell.

[56]  J. Kreidberg,et al.  Development of the renal glomerulus: good neighbors and good fences , 2008, Development.

[57]  M. D. de Caestecker,et al.  Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. , 2008, Developmental biology.

[58]  A. Desai,et al.  Molecular architecture of the kinetochore–microtubule interface , 2008, Nature Reviews Molecular Cell Biology.

[59]  H. A. Hartman,et al.  Cessation of renal morphogenesis in mice. , 2007, Developmental biology.

[60]  M. Busslinger,et al.  Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors , 2007, Nature.

[61]  A. McMahon,et al.  Wnt/β-catenin signaling regulates nephron induction during mouse kidney development , 2007, Development.

[62]  R. Baldock,et al.  A high-resolution anatomical ontology of the developing murine genitourinary tract. , 2007, Gene expression patterns : GEP.

[63]  G. Dressler,et al.  Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney , 2006, The EMBO journal.

[64]  A. McMahon,et al.  Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development , 2005, Development.

[65]  C. Cebrián,et al.  Morphometric index of the developing murine kidney , 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

[66]  A. Kania,et al.  Requirement of Lim1 for female reproductive tract development , 2004, Development.

[67]  Gregor Eichele,et al.  GenePaint.org: an atlas of gene expression patterns in the mouse embryo , 2004, Nucleic Acids Res..

[68]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[69]  J. Ellenberg,et al.  NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization , 2003, The Journal of cell biology.

[70]  C. Mendelsohn,et al.  Stromal progenitors are important for patterning epithelial and mesenchymal cell types in the embryonic kidney. , 2003, Seminars in cell & developmental biology.

[71]  A. McMahon,et al.  Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain , 2002, Mechanisms of Development.

[72]  M. Busslinger,et al.  Nephric lineage specification by Pax2 and Pax8. , 2002, Genes & development.

[73]  Z. Saifudeen,et al.  Spatial repression of PCNA by p53 during kidney development. , 2002, American journal of physiology. Renal physiology.

[74]  R J Toonen,et al.  Increased throughput for fragment analysis on an ABI PRISM 377 automated sequencer using a membrane comb and STRand software. , 2001, BioTechniques.

[75]  G. Dressler,et al.  Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene. , 2001, Development.

[76]  M. Walker Drug target discovery by gene expression analysis: cell cycle genes. , 2001, Current cancer drug targets.

[77]  F. Guillemot,et al.  Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells , 2001, Cell.

[78]  Philippe Soriano,et al.  Widespread recombinase expression using FLPeR (Flipper) mice , 2000, Genesis.

[79]  D. Alcorn,et al.  Development of the renal interstitium , 1999, Pediatric Nephrology.

[80]  Philippe Soriano Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.

[81]  A. McMahon,et al.  Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase , 1998, Current Biology.

[82]  G. Wahl,et al.  PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. , 1998, Molecular cell.

[83]  P. Gruss,et al.  The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas , 1997, Nature.

[84]  E. Lai,et al.  Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. , 1996, Genes & development.

[85]  P. Gruss,et al.  Pax-2 controls multiple steps of urogenital development. , 1995, Development.

[86]  W. Dobyns,et al.  Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux , 1995, Nature Genetics.

[87]  A. McMahon,et al.  Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 , 1994, Nature.

[88]  G. Dressler,et al.  Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development. , 1993, Development.

[89]  G. Dressler,et al.  Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[90]  G. Dressler Pax-2 is a DNA-binding protein in embryonic kidney and Wilms tumor , 1992 .

[91]  K. Lemley,et al.  Anatomy of the renal interstitium. , 1991, Kidney international.

[92]  P. Gruss,et al.  Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. , 1990, Development.

[93]  L. Saxén Organogenesis of the kidney , 1987 .

[94]  B. Hogan,et al.  Manipulating the mouse embryo: A laboratory manual , 1986 .