Catalyst free sequential one‐pot reaction for the synthesis of 3‐indole propanoates/propanoic acid/propanamides as antituberculosis agents

[1]  V. Gopalakrishnan,et al.  ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models , 2020, Molecules.

[2]  Wan‐Xi Peng,et al.  Heterogeneous SO 3 H @ Fe 3 O 4 magnetic nanocatalyst as an efficient and reusable medium for the synthesis of 3,3′‐(arylmethylene)‐bis‐(4‐hydroxycoumarin), bis‐(indolyl)‐methane, and 1,8‐dioxo‐octahydroxanthene derivatives , 2020, Journal of the Chinese Chemical Society.

[3]  K. Rangappa,et al.  Synthesis and biological evaluation of theophylline acetohydrazide hydrazone derivatives as antituberculosis agents , 2020, Journal of the Chinese Chemical Society.

[4]  Kobra Nikoofar,et al.  Ultrasound‐assisted synthesis of 3‐(1‐(2‐(1 H ‐indol‐3‐yl)ethyl)‐2‐aryl‐6,6‐dimethyl‐4‐oxo‐4,5,6,7‐tetrahydro‐1 H ‐indol‐3‐yl)indolin‐2‐ones by novel core‐shell bio‐based nanocatalyst anchoring sulfonated L ‐histidine on magnetized silica (SO 3 H‐ L ‐His@SiO 2 ‐nano Fe 3 O 4 ) , 2020 .

[5]  M. Bakherad,et al.  Ligand‐free, copper‐catalyzed, one‐pot, three‐component synthesis of novel 1,2,3‐triazole‐linked indoles in magnetized water , 2019, Journal of the Chinese Chemical Society.

[6]  J. Charbonnier,et al.  Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner , 2018, The FEBS journal.

[7]  R. Hassanien,et al.  Design, synthesis, and characterization of novel pyrimidines bearing indole as antimicrobial agents , 2018, Journal of the Chinese Chemical Society.

[8]  S. Rangappa,et al.  A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression , 2018, Molecular and Cellular Biochemistry.

[9]  Basappa,et al.  Novel oxolane derivative DMTD mitigates high glucose‐induced erythrocyte apoptosis by regulating oxidative stress , 2017, Toxicology and applied pharmacology.

[10]  K. Rangappa,et al.  Regioselective synthesis and biological studies of novel 1-aryl-3, 5-bis (het) aryl pyrazole derivatives as potential antiproliferative agents , 2016, Molecular and Cellular Biochemistry.

[11]  K. Rangappa,et al.  Induction of apoptosis and downregulation of ERα in DMBA-induced mammary gland tumors in Sprague–Dawley rats by synthetic 3,5-disubstituted isoxazole derivatives , 2016, Molecular and Cellular Biochemistry.

[12]  Basappa,et al.  Platelet protective efficacy of 3,4,5 trisubstituted isoxazole analogue by inhibiting ROS-mediated apoptosis and platelet aggregation , 2016, Molecular and Cellular Biochemistry.

[13]  K. Rangappa,et al.  Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivatives. , 2015, Bioorganic & medicinal chemistry letters.

[14]  Jens Oelerich,et al.  Alkylidene malonates and α,β-unsaturated α'-hydroxyketones as practical substrates for vinylogous Friedel-Crafts alkylations in water catalysed by scandium(III) triflate/SDS. , 2015, Organic & biomolecular chemistry.

[15]  S. Shashikanth,et al.  ZnO: An Ecofriendly, Green Nano‐catalyst for the Synthesis of Pyrazole Derivatives under Aqueous Media , 2014 .

[16]  K. Rangappa,et al.  ZrO2-supported Cu(II)–β-cyclodextrin complex: construction of 2,4,5-trisubstituted-1,2,3-triazoles via azide–chalcone oxidative cycloaddition and post-triazole alkylation , 2014 .

[17]  L. Gentilucci,et al.  An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation , 2014 .

[18]  K. B. Harsha,et al.  Easy access for the synthesis of 2-aryl 2,3-dihydroquinazolin-4(1H)-ones using gem-dibromomethylarenes as synthetic aldehyde equivalent , 2014 .

[19]  K. Rangappa,et al.  Synthesis and antiproliferative effect of novel 4-thiazolidinone-, pyridine- and piperazine-based conjugates on human leukemic cells. , 2014, European journal of medicinal chemistry.

[20]  M. Kerr,et al.  Scandium triflate-catalyzed nucleophilic additions to indolylmethyl Meldrum's acid derivatives via a gramine-type fragmentation: synthesis of substituted indolemethanes. , 2013, The Journal of organic chemistry.

[21]  T. R. Swaroop,et al.  Synthetic utility of propylphosphonic anhydride-DMSO media. An efficient one-pot three-component synthesis of 2-arylquinolines. , 2013 .

[22]  Jing Wu,et al.  Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands. , 2013, The Journal of organic chemistry.

[23]  I. Raheem,et al.  Sustainable practices in medicinal chemistry: current state and future directions. , 2013, Journal of medicinal chemistry.

[24]  K. B. Harsha,et al.  T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols , 2012 .

[25]  A. C. Vinayaka,et al.  An Easy Access to 4,5-Disubstituted Thiazoles via Base-Induced Click Reaction of Active Methylene Isocyanides with Methyl Dithiocarboxylates , 2012 .

[26]  S. Hashimoto,et al.  Catalytic enantioselective C-H functionalization of indoles with α-diazopropionates using chiral dirhodium(II) carboxylates : asymmetric synthesis of the (+)-α-methyl-3-indolylacetic acid fragment of acremoauxin A , 2011 .

[27]  J. Panek,et al.  Total synthesis of (+)-isatisine A. , 2011, Organic letters.

[28]  S. Genovese,et al.  Ytterbium triflate catalyzed synthesis of β-functionalized indole derivatives , 2011 .

[29]  S. Hanessian,et al.  Applications of organocatalytic asymmetric synthesis to drug prototypes--dual action and selective inhibitors of n-nitric oxide synthase with activity against the 5-HT1D/1B subreceptors. , 2011, Organic letters.

[30]  T. Akiyama,et al.  Enantioselective Friedel-Crafts alkylation reaction of indoles with alpha,beta-unsaturated acyl phosphonates catalyzed by chiral phosphoric acid. , 2010, Chemical communications.

[31]  Xiaoming Feng,et al.  N,N′-Dioxide–scandium(III) complex catalyzed highly enantioselective Friedel–Crafts alkylation of indole to alkylidene malonates , 2010 .

[32]  M. Paixão,et al.  Acyl phosphonates: good hydrogen bond acceptors and ester/amide equivalents in asymmetric organocatalysis. , 2010, Journal of the American Chemical Society.

[33]  Kan Wang,et al.  Cyanoacetamide MCR (III): three-component Gewald reactions revisited. , 2010, Journal of combinatorial chemistry.

[34]  Xiaoming Feng,et al.  Enantioselective Friedel-Crafts alkylation of indoles with alkylidene malonates catalyzed by N,N'-dioxide-scandium(III) complexes: asymmetric synthesis of beta-carbolines. , 2009, Chemistry.

[35]  P. Singh,et al.  Highly enantioselective Friedel-Crafts reaction of indoles with 2-enoylpyridine 1-oxides catalyzed by chiral pyridine 2,6-bis(5',5'-diphenyloxazoline)-Cu(II) complexes. , 2008, Organic letters.

[36]  M. Hager,et al.  Dependence of enantioselectivity on the ligand/metal ratio in the asymmetric Michael addition of indole to benzylidene malonates: electronic influence of substrates. , 2008, Chemistry.

[37]  A. Fontana,et al.  TiCl4/Et3N-promoted three-component condensation between aromatic heterocycles, aldehydes, and active methylene compounds. , 2008, The Journal of organic chemistry.

[38]  A. Palmieri,et al.  Simplified synthesis of 3-(1-arylsulfonylalkyl) indoles and their reaction with Reformatsky reagents. , 2007, The Journal of organic chemistry.

[39]  Jian Zhou,et al.  Modular synthesis of chiral homo- and heterotrisoxazolines. Improving the enantioselectivity in the asymmetric Michael addition of indole to benzylidene malonate. , 2005, The Journal of organic chemistry.

[40]  Jian Zhou,et al.  Controllable enantioselective Friedel-Crafts reaction between indoles and alkylidene malonates catalyzed by pseudo-C3-symmetric trisoxazoline copperII complexes. , 2004, The Journal of organic chemistry.

[41]  K. K. Lo,et al.  Luminescent rhenium(I) diimine indole conjugates--photophysical, electrochemical and protein-binding properties. , 2003, Chemical communications.

[42]  Jian Zhou,et al.  Sidearm effect: improvement of the enantiomeric excess in the asymmetric Michael addition of indoles to alkylidene malonates. , 2002, Journal of the American Chemical Society.

[43]  Peter G Schultz,et al.  A combinatorial scaffold approach toward kinase-directed heterocycle libraries. , 2002, Journal of the American Chemical Society.

[44]  W. Zhuang,et al.  Catalytic enantioselective alkylation of heteroaromatic compounds using alkylidene malonates , 2001 .

[45]  L. Jeannin,et al.  A general preparation of β-substituted tryptophan esters , 1995 .

[46]  A. Andreani,et al.  Indole derivatives as agrochemicals , 1988 .

[47]  O. Yonemitsu,et al.  Meldrum's Acid in Organic Synthesis. V. Versatile One-pot Synthesis of Indolepropionic Esters via Simultaneous Condensation of Three Different Carbon Components, Indole, Aldehydes and Meldrum's Acid , 1982 .

[48]  O. Yonemitsu,et al.  Meldrum's acid in organic synthesis. 1. A convenient one-pot synthesis of ethyl indolepropionates , 1978 .

[49]  A. Arieff,et al.  TOXICITY OF PYRIDINE IN MAN , 1943 .