Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies.
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[1] R. Scheller,et al. Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells , 1998, Cell.
[2] M. Roussel,et al. Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture , 2004, The Journal of cell biology.
[3] W. Nelson,et al. A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity , 2007, The Journal of cell biology.
[4] B. Honig,et al. Nectin ectodomain structures reveal a canonical adhesive interface , 2012, Nature Structural &Molecular Biology.
[5] D. Yamazaki,et al. Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion , 2006, Journal of Cell Science.
[6] B. Geiger,et al. Changes in membrane-microfilament interaction in intercellular adherens junctions upon removal of extracellular Ca2+ ions , 1986, The Journal of cell biology.
[7] W. Weis,et al. Structure and biochemistry of cadherins and catenins. , 2009, Cold Spring Harbor perspectives in biology.
[8] N. Perrimon,et al. The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway. , 2001, Development.
[9] Anthony Bretscher,et al. Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network. , 2011, Trends in cell biology.
[10] J. Malsam,et al. Membrane traffic in the secretory pathway , 2008, Cellular and Molecular Life Sciences.
[11] C. Favard,et al. N-cadherin/p120 Catenin Association at Cell-Cell Contacts Occurs in Cholesterol-rich Membrane Domains and Is Required for RhoA Activation and Myogenesis* , 2009, The Journal of Biological Chemistry.
[12] William I. Weis,et al. Deconstructing the Cadherin-Catenin-Actin Complex , 2005, Cell.
[13] M. Silverberg,et al. Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn’s disease , 2009, Gut.
[14] A. Ivanov,et al. Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. , 2004, Molecular biology of the cell.
[15] A. G. Herreros,et al. The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells , 2000, Nature Cell Biology.
[16] B. Baum,et al. Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability , 2008, Current Biology.
[17] S. Salvarezza,et al. Clathrin is a key regulator of basolateral polarity , 2008, Nature.
[18] S. Karki,et al. Dynein binds to β-catenin and may tether microtubules at adherens junctions , 2001, Nature Cell Biology.
[19] J. Bonifacino,et al. Signals for sorting of transmembrane proteins to endosomes and lysosomes. , 2003, Annual review of biochemistry.
[20] Keith R. Johnson,et al. E-Cadherin/Catenin Complexes Are Formed Cotranslationally in the Endoplasmic Reticulum/Golgi Compartments , 2008, Cell communication & adhesion.
[21] M. Takeichi,et al. Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping , 2011, The Journal of cell biology.
[22] H. Höfler,et al. Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences. , 2001, Journal of molecular biology.
[23] V. Hsu,et al. Transport at the recycling endosome. , 2010, Current opinion in cell biology.
[24] F. Autschbach,et al. Inflammatory bowel disease is associated with changes of enterocytic junctions. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[25] W. Nelson,et al. Competitive Regulation of E-Cadherin JuxtaMembrane Domain Degradation by p120-Catenin Binding and Hakai-Mediated Ubiquitination , 2012, PloS one.
[26] Timothy J Mitchison,et al. Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton. , 2002, Chemistry & biology.
[27] Ehud Goldin,et al. Identification and Characterization of Nonmuscle Myosin II-C, a New Member of the Myosin II Family* , 2004, Journal of Biological Chemistry.
[28] I. Macara,et al. Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. , 2006, Molecular biology of the cell.
[29] C. D. dos Remedios,et al. Actin binding proteins: regulation of cytoskeletal microfilaments. , 2003, Physiological reviews.
[30] E. Fuchs,et al. Hyperproliferation and Defects in Epithelial Polarity upon Conditional Ablation of α-Catenin in Skin , 2001, Cell.
[31] E. Perez,et al. p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression , 2008, The Journal of cell biology.
[32] E D Salmon,et al. Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cells. , 2000, Molecular biology of the cell.
[33] Laura Fernández-Martín,et al. Adherens junctions connect stress fibres between adjacent endothelial cells , 2010, BMC Biology.
[34] M. Ikura,et al. The three-dimensional structure of the cadherin-catenin complex. , 2012, Sub-cellular biochemistry.
[35] K. Miyaguchi,et al. Ultrastructure of the zonula adherens revealed by rapid-freeze deep-etching. , 2000, Journal of structural biology.
[36] A. Ivanov,et al. Nonredundant roles of cytoplasmic β- and γ-actin isoforms in regulation of epithelial apical junctions , 2012, Molecular biology of the cell.
[37] S. Tsukita,et al. Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization , 2007, The Journal of cell biology.
[38] R. Singh,et al. An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization , 2012, Molecular biology of the cell.
[39] Z. Chen,et al. Downregulation of E-Cadherin enhances proliferation of head and neck cancer through transcriptional regulation of EGFR , 2011, Molecular Cancer.
[40] J. Weiner,et al. ALCAM Regulates Motility, Invasiveness, and Adherens Junction Formation in Uveal Melanoma Cells , 2012, PloS one.
[41] J. Stow,et al. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. , 1999 .
[42] G. Breitwieser. Extracellular calcium as an integrator of tissue function. , 2008, The international journal of biochemistry & cell biology.
[43] Mark J. Bowser,et al. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. , 2006, Cancer research.
[44] E. Schuman,et al. Activity-Regulated N-Cadherin Endocytosis , 2007, Neuron.
[45] Elaine Fuchs,et al. Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion , 2000, Cell.
[46] M. Ringwald,et al. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[47] M. Takeichi,et al. EPLIN mediates linkage of the cadherin–catenin complex to F-actin and stabilizes the circumferential actin belt , 2008, Proceedings of the National Academy of Sciences.
[48] Y. Takai,et al. Nectin and afadin: novel organizers of intercellular junctions , 2003, Journal of Cell Science.
[49] A. Bershadsky,et al. Mammalian diaphanous-related formin Dia1 controls the organization of E-cadherin-mediated cell-cell junctions , 2007, Journal of Cell Science.
[50] D. McKay,et al. Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent , 2012, PloS one.
[51] Y. Matsuoka,et al. Adducin: structure, function and regulation , 2000, Cellular and Molecular Life Sciences CMLS.
[52] K. Syrigos,et al. Expression of catenins and E‐cadherin during epithelial restitution in inflammatory bowel disease , 1998, The Journal of pathology.
[53] S. Munro,et al. The small G proteins of the Arf family and their regulators. , 2007, Annual review of cell and developmental biology.
[54] Manisha Sharma,et al. IQ-domain GTPase-activating Protein 1 Regulates β-Catenin at Membrane Ruffles and Its Role in Macropinocytosis of N-cadherin and Adenomatous Polyposis Coli* , 2007, Journal of Biological Chemistry.
[55] Cynthia L. Adams,et al. Mechanisms of Epithelial Cell–Cell Adhesion and Cell Compaction Revealed by High-resolution Tracking of E-Cadherin– Green Fluorescent Protein , 1998, The Journal of cell biology.
[56] E. Ullian,et al. Afadin, A Ras/Rap Effector That Controls Cadherin Function, Promotes Spine and Excitatory Synapse Density in the Hippocampus , 2012, The Journal of Neuroscience.
[57] Christopher S. Chen,et al. Mechanotransduction in development: a growing role for contractility , 2009, Nature Reviews Molecular Cell Biology.
[58] A. Ivanov,et al. Spectrin-adducin membrane skeleton , 2011, Bioarchitecture.
[59] A. Pendergast,et al. Regulation of Cell-Cell Adhesion by Abi/Diaphanous Complexes , 2009, Molecular and Cellular Biology.
[60] U. Wolfrum,et al. Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin–catenins complex , 2000, The EMBO journal.
[61] S. Yonemura,et al. α-Catenin as a tension transducer that induces adherens junction development , 2010, Nature Cell Biology.
[62] C. Hartmann,et al. Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation , 2011, Nature Cell Biology.
[63] N. Ueno,et al. Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis , 2010, Development.
[64] Ken W. Y. Cho,et al. TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. , 2007, Genes & development.
[65] J. Stow,et al. The ins and outs of E-cadherin trafficking. , 2004, Trends in cell biology.
[66] M. McNiven,et al. Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation. , 2009, Molecular biology of the cell.
[67] Akinao Nose,et al. Localization of specificity determining sites in cadherin cell adhesion molecules , 1990, Cell.
[68] A. Ridley,et al. p120 Catenin Associates with Microtubules , 2004, Journal of Biological Chemistry.
[69] F. Braet,et al. New anti‐actin drugs in the study of the organization and function of the actin cytoskeleton , 1999, Microscopy research and technique.
[70] T. Svitkina,et al. The cytoskeletal mechanisms of cell–cell junction formation in endothelial cells , 2012, Molecular biology of the cell.
[71] Mala Murthy,et al. Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. , 2005, Developmental cell.
[72] D. Davies,et al. Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches. , 2009, The Journal of allergy and clinical immunology.
[73] K. Burridge,et al. P120 Catenin Regulates the Actin Cytoskeleton via Rho Family Gtpases , 2000, The Journal of cell biology.
[74] T. Pollard,et al. EPLIN regulates actin dynamics by cross-linking and stabilizing filaments , 2003, The Journal of cell biology.
[75] A. Nagafuchi,et al. Defining the Roles of β-catenin and Plakoglobin in Cell-cell adhesion: Isolation of β-catenin/plakoglobin-deficient F9 Cells , 2005 .
[76] E. Dejana,et al. VE-Cadherin-Mediated Cell-Cell Interaction Suppresses Sprouting via Signaling to MLC2 Phosphorylation , 2009, Current Biology.
[77] F. Matsumura,et al. Myosin light chain kinases and phosphatase in mitosis and cytokinesis. , 2011, Archives of biochemistry and biophysics.
[78] Wenxing Chen,et al. Preparation and Characterization of Hot Melt Copolyester (PBTI) Ultrafine Particles and Their Effect on the Anti-Pilling Performance of Polyester/Cotton Fabrics , 2018, Polymers.
[79] K. Syrigos,et al. Expression patterns of alpha-, beta- and gamma-catenin in pancreatic cancer: correlation with E-cadherin expression, pathological features and prognosis. , 2001, Anticancer research.
[80] Chi Wang,et al. Interaction with Suv39H1 is Critical for Snail-mediated E-cadherin Repression in Breast Cancer , 2012, Oncogene.
[81] T. Lecuit,et al. Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis , 2011, Nature Cell Biology.
[82] W. Weis,et al. Re-solving the Cadherin-Catenin-Actin Conundrum* , 2006, Journal of Biological Chemistry.
[83] G. Christofori,et al. Tumor progression induced by the loss of E-cadherin independent of β-catenin/Tcf-mediated Wnt signaling , 2007, Oncogene.
[84] J. Ervasti,et al. β-Actin specifically controls cell growth, migration, and the G-actin pool , 2011, Molecular biology of the cell.
[85] A. Russell,et al. Abrogation of E‐Cadherin‐Mediated Cell–Cell Contact in Mouse Embryonic Stem Cells Results in Reversible LIF‐Independent Self‐Renewal , 2009, Stem cells.
[86] T. Stradal,et al. Protein complexes regulating Arp2/3-mediated actin assembly. , 2006, Current opinion in cell biology.
[87] C. Krummenacher,et al. Glycoprotein D actively induces rapid internalization of two nectin-1 isoforms during herpes simplex virus entry. , 2010, Virology.
[88] Anthony A. Hyman,et al. Growth, fluctuation and switching at microtubule plus ends , 2009, Nature Reviews Molecular Cell Biology.
[89] M. Barth,et al. The junctions that don’t fit the scheme: special symmetrical cell-cell junctions of their own kind , 2009, Cell and Tissue Research.
[90] Takuya Suzuki. Regulation of intestinal epithelial permeability by tight junctions , 2012, Cellular and Molecular Life Sciences.
[91] S. Almo,et al. Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion , 2012, Proceedings of the National Academy of Sciences.
[92] J. Hardin,et al. The secret life of α-catenin: Moonlighting in morphogenesis , 2011, The Journal of cell biology.
[93] A. Baines,et al. Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. , 2001, Physiological reviews.
[94] P. Stern,et al. Epithelial-mesenchymal transition events during human embryonic stem cell differentiation. , 2007, Cancer research.
[95] B. Gumbiner,et al. E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions. , 2007, Molecular biology of the cell.
[96] A. Ivanov,et al. Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility , 2009, BMC Cell Biology.
[97] Hans Clevers,et al. Wnt/β-Catenin Signaling in Development and Disease , 2006, Cell.
[98] A. Nicola,et al. Roles for Endocytosis and Low pH in Herpes Simplex Virus Entry into HeLa and Chinese Hamster Ovary Cells , 2003, Journal of Virology.
[99] E. M. De La Cruz,et al. Relating biochemistry and function in the myosin superfamily. , 2004, Current opinion in cell biology.
[100] Membrane traffic in the secretory pathway , 2008, Cellular and Molecular Life Sciences.
[101] S. Hirohashi,et al. Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization , 1992, Cell.
[102] M. Zhang,et al. Targeting of SNAP-23 and SNAP-25 in Polarized Epithelial Cells* , 1998, The Journal of Biological Chemistry.
[103] N. Hirokawa,et al. Interactions between actin filaments and between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear , 1982, The Journal of cell biology.
[104] A. Yap,et al. Cinderella no longer: α-catenin steps out of cadherin's shadow , 2006, Journal of Cell Science.
[105] K. Okawa,et al. Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins. , 2008, Biochemistry.
[106] Francisco Portillo,et al. The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression , 2000, Nature Cell Biology.
[107] M. Bailly,et al. Actin at cell-cell junctions is composed of two dynamic and functional populations , 2005, Journal of Cell Science.
[108] D. Grunwald,et al. Epithelial Protein Lost In Neoplasm (EPLIN) Interacts with α-Catenin and Actin Filaments in Endothelial Cells and Stabilizes Vascular Capillary Network in Vitro , 2011, The Journal of Biological Chemistry.
[109] J. Klingelhöfer,et al. Dynamic Interplay between Adhesive and Lateral E-Cadherin Dimers , 2002, Molecular and Cellular Biology.
[110] M. Takeichi. The cadherin superfamily in neuronal connections and interactions , 2007, Nature Reviews Neuroscience.
[111] J. Papkoff,et al. Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly , 1994, The Journal of cell biology.
[112] R. Parton,et al. Characterization of E-cadherin Endocytosis in Isolated MCF-7 and Chinese Hamster Ovary Cells , 2003, Journal of Biological Chemistry.
[113] G. Palade,et al. JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA , 1963, The Journal of cell biology.
[114] V. Nizet,et al. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst , 2010, Nature.
[115] C. D’Souza-Schorey,et al. ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly , 2002, Nature Cell Biology.
[116] C. V. Van Itallie,et al. Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia , 2012, Molecular biology of the cell.
[117] E. Dejana,et al. p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin. , 2005, Molecular biology of the cell.
[118] J. Ervasti,et al. γ-Actin is required for cytoskeletal maintenance but not development , 2009, Proceedings of the National Academy of Sciences.
[119] A. Spang. On vesicle formation and tethering in the ER-Golgi shuttle. , 2009, Current opinion in cell biology.
[120] M. Peifer,et al. Rab11 Helps Maintain Apical Crumbs and Adherens Junctions in the Drosophila Embryonic Ectoderm , 2009, PloS one.
[121] K. Kaibuchi,et al. Numb controls E-cadherin endocytosis through p120 catenin with aPKC , 2011, Molecular biology of the cell.
[122] A. Nakagawa,et al. Crystal Structure of the cis-Dimer of Nectin-1 , 2011, The Journal of Biological Chemistry.
[123] Elizabeth R. Smith,et al. Disabled-2 Is an Epithelial Surface Positioning Gene* , 2007, Journal of Biological Chemistry.
[124] Marc D. H. Hansen,et al. A zyxin-nectin interaction facilitates zyxin localization to cell-cell adhesions. , 2011, Biochemical and biophysical research communications.
[125] D. Huntsman,et al. Type Iγ phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with μ1B adaptin , 2007, The Journal of cell biology.
[126] A. Ivanov,et al. Adducins regulate remodeling of apical junctions in human epithelial cells. , 2010, Molecular biology of the cell.
[127] Jan Schmoranzer,et al. Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells , 2003, Nature Cell Biology.
[128] R. Adelstein,et al. Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies , 1995, Journal of Muscle Research & Cell Motility.
[129] E. Wolf,et al. A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation , 2010, PloS one.
[130] H. Pasolli,et al. Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[131] G. Thomas. Spectrin: The ghost in the machine , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.
[132] G. Borisy,et al. Cadherin-mediated regulation of microtubule dynamics , 2000, Nature Cell Biology.
[133] B. Honig,et al. Thinking outside the cell: how cadherins drive adhesion. , 2012, Trends in cell biology.
[134] Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. , 1999, The Journal of cell biology.
[135] M. Takeichi,et al. Nectins localize Willin to cell–cell junctions , 2012, Genes to cells : devoted to molecular & cellular mechanisms.
[136] P. Hordijk,et al. Microtubule dynamics and Rac-1 signaling independently regulate barrier function in lung epithelial cells. , 2007, American journal of physiology. Lung cellular and molecular physiology.
[137] T. Deroo,et al. A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition , 2011, PloS one.
[138] S. Yonemura. Cadherin-actin interactions at adherens junctions. , 2011, Current opinion in cell biology.
[139] A. Ivanov,et al. Pharmacological inhibition of endocytic pathways: is it specific enough to be useful? , 2008, Methods in molecular biology.
[140] M. Ozawa,et al. Increased Internalization of p120-uncoupled E-cadherin and a Requirement for a Dileucine Motif in the Cytoplasmic Domain for Endocytosis of the Protein* , 2007, Journal of Biological Chemistry.
[141] J. Ervasti,et al. The Actin Gene Family: Function Follows Isoform , 2010, Cytoskeleton.
[142] N. Hotchin,et al. RAC1 regulates adherens junctions through endocytosis of E-cadherin. , 2001, Molecular biology of the cell.
[143] S. Colgan,et al. Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch. , 2002, American journal of physiology. Cell physiology.
[144] T. Kawauchi,et al. Cell Adhesion and Its Endocytic Regulation in Cell Migration during Neural Development and Cancer Metastasis , 2012, International journal of molecular sciences.
[145] T. Voyno-Yasenetskaya,et al. A ubiquitous membrane fusion protein αSNAP: a potential therapeutic target for cancer, diabetes and neurological disorders? , 2006, Expert opinion on therapeutic targets.
[146] S. Khaitlina. Functional specificity of actin isoforms. , 2001, International review of cytology.
[147] P. Kuo,et al. Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies. , 2012, International journal of biochemistry and molecular biology.
[148] G. Borisy,et al. p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions , 2003, The Journal of cell biology.
[149] E. Sokolov,et al. Adhesive and Lateral E-Cadherin Dimers Are Mediated by the Same Interface , 2003, Molecular and Cellular Biology.
[150] J. Gutkind,et al. VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin , 2006, Nature Cell Biology.
[151] C. L. Jackson,et al. ARF family G proteins and their regulators: roles in membrane transport, development and disease , 2011, Nature Reviews Molecular Cell Biology.
[152] J. Bonifacino,et al. The clathrin adaptor AP-1A mediates basolateral polarity. , 2012, Developmental cell.
[153] K. Tachibana,et al. Two Cell Adhesion Molecules, Nectin and Cadherin, Interact through Their Cytoplasmic Domain–Associated Proteins , 2000, The Journal of cell biology.
[154] Kenneth M. Yamada,et al. Cell-cell adhesion and RhoA-mediated actin polymerization are independent phenomena in microtubule disrupted keratinocytes. , 2002, The Journal of investigative dermatology.
[155] Luis M. Escudero,et al. Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesion. , 2005, Developmental cell.
[156] A. Nusrat,et al. Endocytosis of the apical junctional complex: mechanisms and possible roles in regulation of epithelial barriers , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.
[157] M. Gorospe,et al. Novel roles of hakai in cell proliferation and oncogenesis. , 2009, Molecular biology of the cell.
[158] T. Boggon,et al. C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms , 2002, Science.
[159] J. Klingelhöfer,et al. α-Catenin contributes to the strength of E-cadherin–p120 interactions , 2011, Molecular biology of the cell.
[160] Yih-Tai Chen,et al. Coupling Assembly of the E-Cadherin/β-Catenin Complex to Efficient Endoplasmic Reticulum Exit and Basal-lateral Membrane Targeting of E-Cadherin in Polarized MDCK Cells , 1999, The Journal of cell biology.
[161] N. King,et al. Diverse evolutionary paths to cell adhesion. , 2010, Trends in cell biology.
[162] L. Thim,et al. TFF3 and EGF Induce Different Migration Patterns of Intestinal Epithelial Cells In Vitro and Trigger Increased Internalization of E-cadherin , 2007, Cellular Physiology and Biochemistry.
[163] J. Gordon,et al. Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin , 1995, Science.
[164] Paul A. Janmey,et al. Mechanisms of mechanical signaling in development and disease , 2011, Journal of Cell Science.
[165] Beth L. Pruitt,et al. E-cadherin is under constitutive actomyosin-generated tension that is increased at cell–cell contacts upon externally applied stretch , 2012, Proceedings of the National Academy of Sciences.
[166] F. van Roy,et al. Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer. , 2008, Human molecular genetics.
[167] H. Pasolli,et al. Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer , 2008, Proceedings of the National Academy of Sciences.
[168] J. Miyoshi,et al. Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia , 2011, Journal of Cell Science.
[169] J. Nance,et al. Adherens junctions in C. elegans embryonic morphogenesis. , 2012, Sub-cellular biochemistry.
[170] Jerrold R. Turner,et al. Intestinal mucosal barrier function in health and disease , 2009, Nature Reviews Immunology.
[171] S. Troyanovsky. Adherens junction assembly. , 2012, Sub-cellular biochemistry.
[172] Yun Cui,et al. Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition* , 2011, The Journal of Biological Chemistry.
[173] N. Voelkel,et al. Heterogeneity of barrier function in the lung reflects diversity in endothelial cell junctions. , 2008, Microvascular research.
[174] T. Lecuit,et al. Molecular bases of cell-cell junctions stability and dynamics. , 2009, Cold Spring Harbor perspectives in biology.
[175] Anne Müsch,et al. Microtubule Organization and Function in Epithelial Cells , 2004, Traffic.
[176] J. Coates,et al. Adherens junctions and β-catenin-mediated cell signalling in a non-metazoan organism , 2000, Nature.
[177] K. Node,et al. Endothelial dysfunction as a cellular mechanism for vascular failure. , 2012, American journal of physiology. Heart and circulatory physiology.
[178] W. Birchmeier,et al. Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex , 2002, Nature Cell Biology.
[179] A. Ivanov,et al. Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. , 2003, Molecular biology of the cell.
[180] A. Reynolds,et al. Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. , 2006, Developmental cell.
[181] J. Alexander,et al. The Role of Cadherin Endocytosis in Endothelial Barrier Regulation: Involvement of Protein Kinase C and Actin-Cadherin Interactions , 1998, Inflammation.
[182] B. Fingleton,et al. Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA , 2010, Journal of oncology.
[183] R. Teasdale,et al. EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin , 2007, Journal of Cell Science.
[184] M. Takeichi,et al. Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line , 1994, The Journal of cell biology.
[185] J. Geng,et al. Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis , 2011, Cell Research.
[186] J. Alexander,et al. Role of cadherin internalization in hydrogen peroxide-mediated endothelial permeability. , 1998, Free radical biology & medicine.
[187] Miguel Vicente-Manzanares,et al. Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner , 2008, Nature Cell Biology.
[188] A. Bershadsky. Magic touch: how does cell-cell adhesion trigger actin assembly? , 2004, Trends in cell biology.
[189] J. Sellers,et al. Functional Divergence of Human Cytoplasmic Myosin II , 2003, Journal of Biological Chemistry.
[190] Robert S. Kerbel,et al. E-Cadherin–dependent Growth Suppression is Mediated by the Cyclin-dependent Kinase Inhibitor p27KIP1 , 1998, The Journal of cell biology.
[191] E. Knapik,et al. Sec24D-Dependent Transport of Extracellular Matrix Proteins Is Required for Zebrafish Skeletal Morphogenesis , 2010, PloS one.
[192] G. Hu,et al. Innate Immune Function of the Adherens Junction Protein p120-Catenin in Endothelial Response to Endotoxin , 2011, The Journal of Immunology.
[193] Neil O Carragher,et al. Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development. , 2009, Cancer research.
[194] K. Miranda,et al. A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells* , 2001, The Journal of Biological Chemistry.
[195] A. García de Herreros,et al. Cooperation, amplification, and feed-back in epithelial-mesenchymal transition. , 2012, Biochimica et biophysica acta.
[196] M. Washington,et al. p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. , 2010, The Journal of clinical investigation.
[197] J. Stow,et al. Dynamin-dependent endocytosis is necessary for convergent-extension movements in Xenopus animal cap explants. , 2002, The International journal of developmental biology.
[198] P. M. O'Connor,et al. Helicobacter pylori Activates Calpain via Toll-Like Receptor 2 To Disrupt Adherens Junctions in Human Gastric Epithelial Cells , 2011, Infection and Immunity.
[199] Zhongming Zhao,et al. Adenoma Formation following Limited Ablation of p120-Catenin in the Mouse Intestine , 2011, PloS one.
[200] E. Schuman,et al. Calcium-dependent dynamics of cadherin interactions at cell–cell junctions , 2011, Proceedings of the National Academy of Sciences.
[201] S. Hui,et al. Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins. , 1980, The American journal of physiology.
[202] Eduard Batlle,et al. Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression* , 2002, The Journal of Biological Chemistry.
[203] M. Takeichi,et al. Cadherins: a molecular family important in selective cell-cell adhesion. , 1990, Annual review of biochemistry.
[204] C. Cheng,et al. Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesis , 2010, Proceedings of the National Academy of Sciences.
[205] Miguel Vicente-Manzanares,et al. Non-muscle myosin II takes centre stage in cell adhesion and migration , 2009, Nature Reviews Molecular Cell Biology.
[206] F. Wylie,et al. Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin. , 2004, Molecular biology of the cell.
[207] C. Yeaman,et al. Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells , 2001, The Journal of cell biology.
[208] G. Campadelli-Fiume,et al. αVβ3-Integrin Relocalizes nectin1 and Routes Herpes Simplex Virus to Lipid Rafts , 2011, Journal of Virology.
[209] C. Walsh,et al. Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex , 2004, Nature Genetics.
[210] I. Gelfand,et al. Cell-cell contact changes the dynamics of lamellar activity in nontransformed epitheliocytes but not in their ras-transformed descendants. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[211] Cramer Lp. Organization and polarity of actin filament networks in cells: implications for the mechanism of myosin-based cell motility. , 1999 .
[212] Angélica Figueroa,et al. Biological influence of Hakai in cancer: a 10-year review , 2012, Cancer and Metastasis Reviews.
[213] D. Stephens,et al. Epithelial organization and cyst lumen expansion require efficient Sec13–Sec31-driven secretion , 2012, Journal of Cell Science.
[214] M. Takeichi,et al. Adherens junction: molecular architecture and regulation. , 2009, Cold Spring Harbor perspectives in biology.
[215] A. Frangakis,et al. The molecular architecture of cadherins in native epidermal desmosomes , 2007, Nature.
[216] V. Quaranta,et al. Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection between β-Catenin Pools , 2009, PloS one.
[217] P. Saftig,et al. ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis. , 2008, The Journal of investigative dermatology.
[218] Albert B. Reynolds,et al. A core function for p120-catenin in cadherin turnover , 2003, The Journal of cell biology.
[219] J. Sellers,et al. Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis , 2012, Proceedings of the National Academy of Sciences.
[220] Khadar M. Abdi,et al. Adducin promotes micrometer-scale organization of beta2-spectrin in lateral membranes of bronchial epithelial cells. , 2007, Molecular biology of the cell.
[221] W. Nelson,et al. Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. , 2006, Genes & development.
[222] William I. Weis,et al. The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin , 2001, Cell.
[223] F. Wylie,et al. Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis. , 2008, American journal of physiology. Cell physiology.
[224] A. Bresnick. Molecular mechanisms of nonmuscle myosin-II regulation. , 1999, Current opinion in cell biology.
[225] Ju-Seog Lee,et al. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. , 2011, Cancer cell.
[226] Keith R. Johnson,et al. N-cadherin-Catenin Complexes Form Prior to Cleavage of the Proregion and Transport to the Plasma Membrane* , 2003, The Journal of Biological Chemistry.
[227] S. Arase,et al. The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. , 2007, Molecular biology of the cell.
[228] C. Nicholson,et al. Calcium and potassium changes in extracellular microenvironment of cat cerebellar cortex. , 1978, Journal of neurophysiology.
[229] S. Grzesiek,et al. Calcium-dependent homoassociation of E-cadherin by NMR spectroscopy: changes in mobility, conformation and mapping of contact regions. , 2002, Journal of molecular biology.
[230] A. Ivanov,et al. Microtubules regulate disassembly of epithelial apical junctions , 2006, BMC Cell Biology.
[231] M. Ozawa,et al. A dileucine motif in its cytoplasmic domain directs β-catenin-uncoupled E-cadherin to the lysosome , 2007, Journal of Cell Science.
[232] M. Lerch,et al. Dissociation and reassembly of adherens junctions during experimental acute pancreatitis. , 1997, Gastroenterology.
[233] Wei Guo,et al. The exocyst complex in polarized exocytosis. , 2004, International review of cytology.
[234] M. Dohn,et al. A Membrane Fusion Protein αSNAP Is a Novel Regulator of Epithelial Apical Junctions , 2012, PloS one.
[235] B. Gumbiner,et al. Regulation of cadherin-mediated adhesion in morphogenesis , 2005, Nature Reviews Molecular Cell Biology.
[236] M. Ikura,et al. Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion , 2010, Cell.
[237] Wayne A. Hendrickson,et al. Structure-Function Analysis of Cell Adhesion by Neural (N-) Cadherin , 1998, Neuron.
[238] A. Ben-Ze'ev,et al. Epithelial-mesenchymal transition and the invasive potential of tumors. , 2008, Trends in molecular medicine.
[239] T. Galli,et al. v-SNARE cellubrevin is required for basolateral sorting of AP-1B–dependent cargo in polarized epithelial cells , 2007, The Journal of cell biology.
[240] E. Mackow,et al. Pathogenic Hantaviruses Andes Virus and Hantaan Virus Induce Adherens Junction Disassembly by Directing Vascular Endothelial Cadherin Internalization in Human Endothelial Cells , 2010, Journal of Virology.
[241] J. Bousquet,et al. Modulation of cadherin and catenins expression by tumor necrosis factor-alpha and dexamethasone in human bronchial epithelial cells. , 2002, American journal of respiratory cell and molecular biology.
[242] Gordon B. Mills,et al. Derailed endocytosis: an emerging feature of cancer , 2008, Nature Reviews Cancer.
[243] Gerhard Christofori,et al. A causal role for E-cadherin in the transition from adenoma to carcinoma , 1998, Nature.
[244] A. Verin,et al. The role of cytoskeleton in the regulation of vascular endothelial barrier function. , 2008, Microvascular research.
[245] M. Eck,et al. Mechanism and function of formins in the control of actin assembly. , 2007, Annual review of biochemistry.
[246] T. Uemura,et al. Patterning of cell assemblies regulated by adhesion receptors of the cadherin superfamily. , 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[247] J. Hoffman,et al. Ankyrin-G and β2-Spectrin Collaborate in Biogenesis of Lateral Membrane of Human Bronchial Epithelial Cells* , 2007, Journal of Biological Chemistry.
[248] J. Stow,et al. E‐Cadherin Transport from the trans‐Golgi Network in Tubulovesicular Carriers is Selectively Regulated by Golgin‐97 , 2005, Traffic.
[249] C. Cheng,et al. Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes. , 2006, The Journal of endocrinology.
[250] P. Cossart,et al. Successive post‐translational modifications of E‐cadherin are required for InlA‐mediated internalization of Listeria monocytogenes , 2008, Cellular microbiology.
[251] H. Schwarz,et al. E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions , 2005, The EMBO journal.
[252] C. McGlade,et al. Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation. , 2011, Experimental cell research.
[253] W J Nelson,et al. Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells , 1994, The Journal of cell biology.
[254] A. Averbakh,et al. Molecular organization of the desmoglein-plakoglobin complex. , 1998, Journal of cell science.
[255] D. Laurents,et al. The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover. , 2001, The Journal of biological chemistry.
[256] E. Sztul,et al. The Garz Sec7 domain guanine nucleotide exchange factor for Arf regulates salivary gland development in Drosophila , 2011, Cellular logistics.
[257] D. Newgreen,et al. Defining the E-Cadherin Repressor Interactome in Epithelial-Mesenchymal Transition: The PMC42 Model as a Case Study , 2010, Cells Tissues Organs.
[258] K. Tachibana,et al. Nectin-3, a New Member of Immunoglobulin-like Cell Adhesion Molecules That Shows Homophilic and Heterophilic Cell-Cell Adhesion Activities* , 2000, The Journal of Biological Chemistry.
[259] C. Cheng,et al. TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesis. , 2009, Developmental biology.
[260] Fabiana Bahna,et al. Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins , 2011, Nature Structural &Molecular Biology.
[261] A. Ivanov,et al. Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex. , 2005, Molecular biology of the cell.
[262] Y. Takai,et al. Involvement of the Ras-Ras-activated Rab5 Guanine Nucleotide Exchange Factor RIN2-Rab5 Pathway in the Hepatocyte Growth Factor-induced Endocytosis of E-cadherin* , 2006, Journal of Biological Chemistry.
[263] Daniela C. Zarnescu,et al. Apical Spectrin Is Essential for Epithelial Morphogenesis but Not Apicobasal Polarity in Drosophila , 1999, The Journal of cell biology.
[264] M. Llimargas,et al. Adherens junctions and cadherins in Drosophila development. , 2012, Sub-cellular biochemistry.
[265] V. Vasioukhin,et al. Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice. , 2007, Developmental cell.
[266] B. Margolis,et al. PALS1 regulates E-cadherin trafficking in mammalian epithelial cells. , 2007, Molecular biology of the cell.
[267] C. G. Hansen,et al. Molecular mechanisms of clathrin-independent endocytosis , 2009, Journal of Cell Science.
[268] Xianglin Shi,et al. Ethanol disrupts vascular endothelial barrier: implication in cancer metastasis. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.
[269] P. Vincent,et al. Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells , 2003, The Journal of cell biology.
[270] C. Petit,et al. Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis. , 2005, Developmental biology.
[271] William I. Weis,et al. α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly , 2005, Cell.
[272] Mark Peifer,et al. Wnt signaling from development to disease: insights from model systems. , 2009, Cold Spring Harbor perspectives in biology.
[273] A. G. de Herreros,et al. E-cadherin controls β-catenin and NF-κB transcriptional activity in mesenchymal gene expression , 2008, Journal of Cell Science.
[274] M. Itoh,et al. Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. , 1995, Journal of cell science.
[275] C W Turck,et al. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. , 1991, Science.
[276] O. Harrison,et al. Cadherin adhesion depends on a salt bridge at the N-terminus , 2005, Journal of Cell Science.
[277] B. Hogan,et al. Ankyrin-G Is a Molecular Partner of E-cadherin in Epithelial Cells and Early Embryos* , 2007, Journal of Biological Chemistry.
[278] S. Chu,et al. Resolving cadherin interactions and binding cooperativity at the single-molecule level , 2009, Proceedings of the National Academy of Sciences.
[279] T. Sasaki,et al. Similar and differential behaviour between the nectin‐afadin‐ponsin and cadherin‐catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cells , 1999, Genes to cells : devoted to molecular & cellular mechanisms.
[280] I. Gromova,et al. Immediate and Delayed Effects of E-Cadherin Inhibition on Gene Regulation and Cell Motility in Human Epidermoid Carcinoma Cells , 2005, Molecular and Cellular Biology.
[281] P. Donnelly,et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region , 2010 .
[282] C. D’Souza-Schorey. Disassembling adherens junctions: breaking up is hard to do. , 2005, Trends in cell biology.
[283] M. Hostetter,et al. Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans. , 2007, Translational research : the journal of laboratory and clinical medicine.
[284] A. G. de Herreros,et al. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. , 2008, Genes & development.
[285] M. Takeichi,et al. Basal-to-apical cadherin flow at cell junctions , 2007, Nature Cell Biology.
[286] A. Kowalczyk,et al. Regulation of Cadherin Trafficking , 2009, Traffic.
[287] S. Hogan,et al. Intestinal barrier function: molecular regulation and disease pathogenesis. , 2009, The Journal of allergy and clinical immunology.
[288] M. Silverberg,et al. Protein-Tyrosine Phosphatase Sigma Is Associated with Ulcerative Colitis , 2007, Current Biology.
[289] Samantha J. Stehbens,et al. Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts , 2006, Journal of Cell Science.
[290] Samantha J. Stehbens,et al. Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts. , 2005, Molecular biology of the cell.
[291] V. Cerundolo,et al. The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein , 2009 .
[292] V. Bodrikov,et al. Prion Protein Promotes Growth Cone Development through Reggie/Flotillin-Dependent N-Cadherin Trafficking , 2011, The Journal of Neuroscience.
[293] J. Gordon,et al. Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. , 1996, Genes & development.
[294] D. Leckband,et al. Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. , 2011, Physiological reviews.
[295] B. van de Water,et al. Transformation-sensitive changes in expression, localization, and phosphorylation of adducins in renal proximal tubule epithelial cells. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[296] C. Gottardi,et al. Molecular components of the adherens junction. , 2008, Biochimica et biophysica acta.
[297] S. Itoh,et al. Tage4/Nectin-like Molecule-5 Heterophilically trans-Interacts with Cell Adhesion Molecule Nectin-3 and Enhances Cell Migration* , 2003, Journal of Biological Chemistry.
[298] E. Fuchs,et al. Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. , 2002, Developmental cell.
[299] E. Holzbaur,et al. Microtubules Tethered at Epithelial Cell Junctions by Dynein Facilitate Efficient Junction Assembly , 2007, Traffic.
[300] H. Plattner,et al. Reggies/flotillins regulate E-cadherin–mediated cell contact formation by affecting EGFR trafficking , 2012, Molecular biology of the cell.
[301] I. Giannopoulou,et al. Abnormal α‐catenin expression in invasive breast cancer correlates with poor patient survival , 2002 .
[302] N. Hamilton,et al. Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens , 2010, Nature Cell Biology.
[303] P. Vincent,et al. p120-catenin inhibits VE-cadherin internalization through a Rho-independent mechanism. , 2009, Molecular biology of the cell.
[304] D. Saur,et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. , 2009, Gastroenterology.
[305] L Shapiro,et al. Linking molecular affinity and cellular specificity in cadherin-mediated adhesion , 2009, Proceedings of the National Academy of Sciences.
[306] Y. Takai,et al. Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments , 2004, The Journal of cell biology.
[307] D. Richardson,et al. Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal–epithelial transition in breast cancer cells , 2013, Oncogene.
[308] J. Wesseling,et al. Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice , 2011, Disease Models & Mechanisms.
[309] M. Takeichi,et al. Anchorage of Microtubule Minus Ends to Adherens Junctions Regulates Epithelial Cell-Cell Contacts , 2008, Cell.
[310] Tomoatsu Hayashi,et al. PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex. , 2008, Genes & development.
[311] J. Stow,et al. Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin. , 2005, Molecular biology of the cell.
[312] J. Miyoshi,et al. Structural and functional associations of apical junctions with cytoskeleton. , 2008, Biochimica et biophysica acta.
[313] M. Mogensen,et al. Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells. , 2009, Cell motility and the cytoskeleton.
[314] A. Ivanov,et al. A Unique Role for Nonmuscle Myosin Heavy Chain IIA in Regulation of Epithelial Apical Junctions , 2007, PloS one.
[315] D. Leckband,et al. Biophysics of cadherin adhesion. , 2012, Sub-cellular biochemistry.
[316] F. Amblard,et al. Endocytosis is required for E-cadherin redistribution at mature adherens junctions , 2009, Proceedings of the National Academy of Sciences.
[317] C. D’Souza-Schorey,et al. Lysosomal Targeting of E-Cadherin: a Unique Mechanism for the Down-Regulation of Cell-Cell Adhesion during Epithelial to Mesenchymal Transitions , 2005, Molecular and Cellular Biology.
[318] D. Leckband,et al. Calcium site mutations in cadherin: impact on adhesion and evidence of cooperativity. , 2006, Biochemistry.
[319] Kate E. Hawkins,et al. Loss of Function of E-Cadherin in Embryonic Stem Cells and the Relevance to Models of Tumorigenesis , 2010, Journal of oncology.
[320] H. Federoff,et al. Membrane palmitoylated proteins regulate trafficking and processing of nectins. , 2011, European journal of cell biology.
[321] J. Engel,et al. Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. , 1994, European journal of biochemistry.
[322] J. Zallen,et al. Junctional trafficking and epithelial morphogenesis. , 2009, Current opinion in genetics & development.
[323] B. Bonaz,et al. Enterocytic differentiation is modulated by lipid rafts-dependent assembly of adherens junctions. , 2011, Experimental cell research.
[324] M. Takeichi,et al. Roles of cadherins in patterning of the developing brain. , 1997, Developmental neuroscience.
[325] T D Pollard,et al. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. , 2000, Annual review of biophysics and biomolecular structure.
[326] E. Fearon,et al. The SLUG zinc-finger protein represses E-cadherin in breast cancer. , 2002, Cancer research.
[327] R. Harland,et al. Endocytosis Is Required for Efficient Apical Constriction during Xenopus Gastrulation , 2010, Current Biology.
[328] Thomas D Pollard,et al. Regulation of actin filament assembly by Arp2/3 complex and formins. , 2007, Annual review of biophysics and biomolecular structure.
[329] Gerhard Christofori,et al. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer , 2004, Nature Reviews Cancer.
[330] Tony Hunter,et al. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. , 2003, Cancer cell.
[331] Kenneth M. Yamada,et al. Defects in Cell Adhesion and the Visceral Endoderm following Ablation of Nonmuscle Myosin Heavy Chain II-A in Mice* , 2004, Journal of Biological Chemistry.
[332] Tyler E. Miller,et al. Myosin II isoform switching mediates invasiveness after TGF-β–induced epithelial–mesenchymal transition , 2011, Proceedings of the National Academy of Sciences.
[333] N. Hirokawa,et al. Quick-freeze, deep-etch visualization of the cytoskeleton beneath surface differentiations of intestinal epithelial cells , 1981, The Journal of cell biology.
[334] S. Koch,et al. Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion. , 2009, The American journal of pathology.
[335] D. Leckband,et al. Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[336] F. Amblard,et al. New insights into the regulation of E-cadherin distribution by endocytosis. , 2012, International review of cell and molecular biology.
[337] M. Zegers,et al. The Syntaxin 4 N Terminus Regulates Its Basolateral Targeting by Munc18c-dependent and -independent Mechanisms* , 2011, The Journal of Biological Chemistry.
[338] Wenjun Guo,et al. The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.
[339] J. Stow,et al. Protein kinase C regulates endocytosis and recycling of E-cadherin. , 2002, American journal of physiology. Cell physiology.
[340] E. Sokolov,et al. Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly. , 2006, Molecular biology of the cell.
[341] A. Nusrat,et al. Cytokine regulation of tight junctions. , 2009, Biochimica et biophysica acta.
[342] W. Dinjens,et al. E‐cadherin—catenin cell—cell adhesion complex and human cancer , 2000, The British journal of surgery.
[343] A. Franco,et al. Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and γ-secretase-dependent E-cadherin cleavage , 2007, Journal of Cell Science.
[344] T. Matozaki,et al. Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells – regulation by Rho, Rac and Rab small G proteins , 1999, Oncogene.
[345] A. Ivanov,et al. Cytoskeletal regulation of epithelial barrier function during inflammation. , 2010, The American journal of pathology.
[346] V. Bennett,et al. Adducin Is an In Vivo Substrate for Protein Kinase C: Phosphorylation in the MARCKS-related Domain Inhibits Activity in Promoting Spectrin–Actin Complexes and Occurs in Many Cells, Including Dendritic Spines of Neurons , 1998, The Journal of cell biology.
[347] C. Bailly,et al. Effect of microtubule-targeting drugs on cell–cell and cell–matrix junctions in tumor epithelial cells , 2011, Anti-cancer drugs.
[348] S. Alahari,et al. Molecular mechanisms controlling E-cadherin expression in breast cancer. , 2009, Biochemical and biophysical research communications.
[349] C. Ikrényi,et al. Ion concentrations in subcutaneous interstitial fluid: measured versus expected values. , 1988, The American journal of physiology.
[350] Y. Shimono,et al. Immunoglobulin superfamily receptors and adherens junctions. , 2012, Sub-cellular biochemistry.
[351] M. Korpal,et al. The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2* , 2008, Journal of Biological Chemistry.
[352] Soonjin Hong,et al. Spontaneous assembly and active disassembly balance adherens junction homeostasis , 2010, Proceedings of the National Academy of Sciences.
[353] Mitan R. Gokulgandhi,et al. Cadherin Switching and Activation of β-Catenin Signaling Underlie Proinvasive Actions of Calcitonin-Calcitonin Receptor Axis in Prostate Cancer* , 2009, Journal of Biological Chemistry.
[354] E. Nogales. Structural insight into microtubule function. , 2001, Annual review of biophysics and biomolecular structure.
[355] A. Martínez-Palomo,et al. Occluding junctions and cytoskeletal components in a cultured transporting epithelium , 1980, The Journal of cell biology.
[356] C. Arregui,et al. The Protein Tyrosine Phosphatase PTP1B Is Required for Efficient Delivery of N-Cadherin to the Cell Surface , 2010, Molecular biology of the cell.
[357] T. Blackwell,et al. Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress* , 2011, The Journal of Biological Chemistry.
[358] Y. Yagita,et al. The Minimal Essential Unit for Cadherin-mediated Intercellular Adhesion Comprises Extracellular Domains 1 and 2* , 2004, Journal of Biological Chemistry.
[359] Nam‐Gyun Kim,et al. E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components , 2011, Proceedings of the National Academy of Sciences.
[360] J Downward,et al. Raf plus TGFβ-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin , 2006, Oncogene.
[361] K. Irie,et al. Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions. , 2003, Biochemical and biophysical research communications.
[362] A. Kowalczyk,et al. Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling. , 2012, Sub-cellular biochemistry.
[363] C. Yeaman,et al. Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cells , 2004, Journal of Cell Science.
[364] David J. Stephens,et al. Assembly, organization, and function of the COPII coat , 2007, Histochemistry and Cell Biology.
[365] Samantha J. Stehbens,et al. Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens , 2012, Nature Cell Biology.
[366] N. Hamilton,et al. N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway , 2011, Nature Cell Biology.
[367] A. Schürmann,et al. ADP-ribosylation Factor-like GTPase ARFRP1 Is Required for Trans-Golgi to Plasma Membrane Trafficking of E-cadherin* , 2008, Journal of Biological Chemistry.
[368] A. Ivanov. Actin motors that drive formation and disassembly of epithelial apical junctions. , 2008, Frontiers in bioscience : a journal and virtual library.
[369] J. Daniel,et al. A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus*S⃞ , 2008, Journal of Biological Chemistry.
[370] G. Corazza,et al. Altered expression, localization, and phosphorylation of epithelial junctional proteins in celiac disease. , 2006, American journal of clinical pathology.
[371] A. Hopkins,et al. Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms 1 , 2003, The Journal of Immunology.
[372] Albert B. Reynolds,et al. Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion , 2000, The Journal of cell biology.
[373] K. Irie,et al. Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E‐cadherin‐based cell‐cell adhesion , 2003, Genes to cells : devoted to molecular & cellular mechanisms.
[374] T. Renné,et al. Cytoskeleton assembly at endothelial cell–cell contacts is regulated by αII-spectrin–VASP complexes , 2008, The Journal of cell biology.
[375] B. Honig,et al. The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. , 2011, Structure.
[376] Hiroki Oda,et al. Structural and functional diversity of cadherin at the adherens junction , 2011, The Journal of Cell Biology.
[377] R. Götz,et al. Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer. , 2007, Cancer cell.
[378] K. Miranda,et al. Contextual Binding of p120ctn to E-cadherin at the Basolateral Plasma Membrane in Polarized Epithelia* , 2003, Journal of Biological Chemistry.
[379] V. Vasioukhin,et al. Adhesive and signaling functions of cadherins and catenins in vertebrate development. , 2009, Cold Spring Harbor perspectives in biology.
[380] D L Rimm,et al. Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[381] Yinghao Wu,et al. Transforming binding affinities from 3D to 2D with application to cadherin clustering , 2011, Nature.
[382] T. Vandenbos,et al. Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma. , 2001, American journal of physiology. Cell physiology.
[383] Vann Bennett,et al. Membrane domains based on ankyrin and spectrin associated with cell-cell interactions. , 2009, Cold Spring Harbor perspectives in biology.
[384] G. Rogler,et al. Association of the NOD2 genotype with bacterial translocation via altered cell–cell contacts in Crohn's disease patients , 2010, Inflammatory bowel diseases.
[385] J. Catravas,et al. Regulators of endothelial and epithelial barrier integrity and function in acute lung injury. , 2009, Biochemical pharmacology.
[386] K. Kizhatil,et al. Lateral Membrane Biogenesis in Human Bronchial Epithelial Cells Requires 190-kDa Ankyrin-G*[boxs] , 2004, Journal of Biological Chemistry.
[387] A. Yap,et al. The cytoskeleton and classical cadherin adhesions. , 2012, Sub-cellular biochemistry.
[388] E. Kovacs,et al. Cadherin-Directed Actin Assembly E-Cadherin Physically Associates with the Arp2/3 Complex to Direct Actin Assembly in Nascent Adhesive Contacts , 2002, Current Biology.
[389] B. Goud,et al. The trans‐Golgi Network Golgin, GCC185, is Required for Endosome‐to‐Golgi Transport and Maintenance of Golgi Structure , 2007, Traffic.
[390] J. Lieberman,et al. miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases , 2009, PloS one.
[391] Zhi Li,et al. Altered Expression of E-cadherin by Hepatocyte Growth Factor and Effect on the Prognosis of Nasopharyngeal Carcinoma , 2010, Annals of Surgical Oncology.
[392] A. Yap,et al. Microtubule integrity is essential for apical polarization and epithelial morphogenesis in the thyroid. , 2001, Cell motility and the cytoskeleton.
[393] V. Tang,et al. α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction , 2012, The Journal of cell biology.
[394] N. Hirokawa,et al. Mechanism of brush border contractility studied by the quick-freeze, deep-etch method , 1983, The Journal of cell biology.
[395] F. Farrell,et al. Proinflammatory/Profibrotic Effects of Interleukin-17A on Human Proximal Tubule Epithelium , 2009, Nephron Experimental Nephrology.
[396] S. Troyanovsky. Cadherin dimers in cell-cell adhesion. , 2005, European journal of cell biology.
[397] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[398] W. Franke,et al. Discovering the molecular components of intercellular junctions--a historical view. , 2009, Cold Spring Harbor perspectives in biology.
[399] Reinhard Jahn,et al. SNAREs — engines for membrane fusion , 2006, Nature Reviews Molecular Cell Biology.
[400] J. Settleman,et al. p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho , 2006, Cell.
[401] A. Lustig,et al. Calcium binding and homoassociation of E-cadherin domains. , 1997, Biochemistry.
[402] I. Puig,et al. Phosphorylation Regulates the Subcellular Location and Activity of the Snail Transcriptional Repressor , 2003, Molecular and Cellular Biology.
[403] B. Cooper,et al. Reduced cadherin/catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation. , 1999, Laboratory investigation; a journal of technical methods and pathology.
[404] T. Weimbs,et al. Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells. , 1996, Molecular biology of the cell.
[405] T. Harris. Adherens junction assembly and function in the Drosophila embryo. , 2012, International review of cell and molecular biology.
[406] R. Dermietzel,et al. Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study , 1988, The Journal of cell biology.