Proof of concept nanotechnological approach to in vitro targeting of malignant melanoma for enhanced immune checkpoint inhibition
暂无分享,去创建一个
D. Doherty | S. Gray | N. Binsaleh | E. Lioudakis | B. Mohamed | J. O'Leary | Husam Qanash | B. Alharbi | Chandranil H Gharekhan | S. Alharthi | A. Elasbali | Muhammad Mahmoud | Naif K Binsaleh
[1] N. Gleeson,et al. Ex vivo expansion of circulating tumour cells (CTCs) , 2023, Scientific Reports.
[2] G. Kochan,et al. Predictive Biomarkers for Checkpoint Inhibitor Immune-Related Adverse Events , 2023, Cancers.
[3] Z. Tian,et al. NADPH Selective Depletion Nanomedicine‐Mediated Radio‐Immunometabolism Regulation for Strengthening Anti‐PDL1 Therapy against TNBC , 2022, Advanced science.
[4] O. Baffa,et al. Uniform Size PEGylated Iron Oxide Nanoparticles as a Potential Theranostic Agent Synthesized by a Simple Optimized Coprecipitation Route , 2022, Journal of Magnetism and Magnetic Materials.
[5] T. D. de Gruijl,et al. From simplicity to complexity in current melanoma models , 2022, Experimental dermatology.
[6] T. Zhao,et al. BMS‐202, a PD‐1/PD‐L1 inhibitor, decelerates the pro‑fibrotic effects of fibroblasts derived from scar tissues via ERK and TGFβ1/Smad signaling pathways , 2022, Immunity, inflammation and disease.
[7] V. Velcheti,et al. Immunotherapy in non-small cell lung cancer: Past, present, and future directions , 2022, Frontiers in Oncology.
[8] Revisiting checkpoint blockade , 2022, Nature Biotechnology.
[9] Michael R Hamblin,et al. An update on dual targeting strategy for cancer treatment. , 2022, Journal of controlled release : official journal of the Controlled Release Society.
[10] Tingting Meng,et al. Combination of tumor vessel normalization and immune checkpoint blockade for breast cancer treatment via multifunctional nanocomplexes. , 2022, Biomaterials science.
[11] E. Saber,et al. Metformin-loaded ethosomes with promoted anti-proliferative activity in melanoma cell line B16, and wound healing aptitude: Development, characterization and in vivo evaluation. , 2022, International journal of pharmaceutics.
[12] Lanlan Shen,et al. Discovery of benzo[d]isothiazole derivatives as novel scaffold inhibitors targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction through "ring fusion" strategy. , 2022, Bioorganic chemistry.
[13] F. Bray,et al. Global Burden of Cutaneous Melanoma in 2020 and Projections to 2040. , 2022, JAMA dermatology.
[14] M. Bros,et al. Immunomodulatory Properties of Immune Checkpoint Inhibitors—More than Boosting T-Cell Responses? , 2022, Cancers.
[15] Bingjun Sun,et al. Paclitaxel derivative-based liposomal nanoplatform for potentiated chemo-immunotherapy. , 2021, Journal of controlled release : official journal of the Controlled Release Society.
[16] N. Tan,et al. Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy , 2021, Acta pharmaceutica Sinica. B.
[17] C. Genova,et al. Therapeutic Implications of Tumor Microenvironment in Lung Cancer: Focus on Immune Checkpoint Blockade , 2022, Frontiers in Immunology.
[18] T. George,et al. The Role of Immune Checkpoint Blockade in the Hepatocellular Carcinoma: A Review of Clinical Trials , 2021, Frontiers in Oncology.
[19] S. Ladoire,et al. Therapeutic Associations Comprising Anti-PD-1/PD-L1 in Breast Cancer: Clinical Challenges and Perspectives , 2021, Cancers.
[20] Prashanth Rawla,et al. Epidemiology of Melanoma , 2021, Medical sciences.
[21] E. Novellino,et al. Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors. , 2021, Journal of medicinal chemistry.
[22] X. Guan,et al. Thermal-sensitive lipid nanoparticles potentiate anti-PD therapy through enhancing drug penetration and T lymphocytes infiltration in metastatic tumor. , 2021, Cancer letters.
[23] Yu Zheng,et al. Adoptive CD8+T-cell grafted with liposomal immunotherapy drugs to counteract the immune suppressive tumor microenvironment and enhance therapy for melanoma. , 2021, Nanoscale.
[24] Kyoung-Mee Kim,et al. PD-L1 Expression Is Significantly Associated with Tumor Mutation Burden and Microsatellite Instability Score , 2021, Cancers.
[25] Xuesi Chen,et al. Cisplatin Nanoparticles Possess Stronger Anti-tumor Synergy with PD1/PD-L1 Inhibitors than the Parental Drug. , 2021, Acta biomaterialia.
[26] Karin M Torres-Obreque,et al. Building better biobetters: from fundamentals to industrial application. , 2021, Drug discovery today.
[27] Khaled S. Allemailem,et al. Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics , 2021, International journal of nanomedicine.
[28] Takashi Nakamura,et al. STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation , 2021, Journal for ImmunoTherapy of Cancer.
[29] Yongheng Chen,et al. Nanomaterials for cancer therapy: current progress and perspectives , 2021, Journal of Hematology & Oncology.
[30] Yilun Liu,et al. Molecular Targeted Agent and Immune Checkpoint Inhibitor Co-Loaded Thermosensitive Hydrogel for Synergistic Therapy of Rectal Cancer , 2021, Frontiers in Pharmacology.
[31] Baolin Zhang,et al. Cancer Immunotherapy Update: FDA-Approved Checkpoint Inhibitors and Companion Diagnostics , 2021, The AAPS Journal.
[32] B. Dong,et al. IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor , 2021, Nature Immunology.
[33] D. DeNardo,et al. Rethinking immune checkpoint blockade: ‘Beyond the T cell’ , 2021, Journal for ImmunoTherapy of Cancer.
[34] P. Varamini,et al. Nanotechnology-based platforms to improve immune checkpoint blockade efficacy in cancer therapy. , 2020, Future oncology.
[35] S. Botchway,et al. Porous Carbon Microparticles as Vehicles for the Intracellular Delivery of Molecules , 2020, Frontiers in Chemistry.
[36] Yoshimasa Tanaka,et al. Synthesis and Evaluation of Biphenyl-1,2,3-Triazol-Benzonitrile Derivatives as PD-1/PD-L1 Inhibitors , 2020, ACS omega.
[37] Y. Luan,et al. Rational Design of a Robust Antibody-Like Small Molecule Inhibitor Nanoplatform for Enhanced Photoimmunotherapy. , 2020, ACS applied materials & interfaces.
[38] Xiaole Shirley Liu,et al. TIMER2.0 for analysis of tumor-infiltrating immune cells , 2020, Nucleic Acids Res..
[39] T. Lüscher,et al. Therapeutic Implications , 2020, The Endothelium: Modulator of Cardiovascular Function.
[40] Zhengping Hu,et al. PCC0208025 (BMS202), a small molecule inhibitor of PD-L1, produces an antitumor effect in B16-F10 melanoma-bearing mice , 2020, PloS one.
[41] M. Mingari,et al. Targeted Therapies: Friends or Foes for Patient’s NK Cell-Mediated Tumor Immune-Surveillance? , 2020, Cancers.
[42] Hongyang Wang,et al. Progress and Challenges in Precise Treatment of Tumors With PD-1/PD-L1 Blockade , 2020, Frontiers in Immunology.
[43] J. Wolchok,et al. Long-Term Outcomes and Responses to Retreatment in Patients With Melanoma Treated With PD-1 Blockade. , 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[44] J. Egen,et al. Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials. , 2020, Immunity.
[45] T. Ashizawa,et al. Antitumor activity of the PD-1/PD-L1 binding inhibitor BMS-202 in the humanized MHC-double knockout NOG mouse. , 2019, Biomedical research.
[46] R. Zhang,et al. Immune Checkpoint Blockade Mediated by a Small-Molecule Nanoinhibitor Targeting the PD-1/PD-L1 Pathway Synergizes with Photodynamic Therapy to Elicit Antitumor Immunity and Antimetastatic Effects on Breast Cancer. , 2019, Small.
[47] P. Hegde,et al. Safety, Clinical Activity, and Biological Correlates of Response in Patients with Metastatic Melanoma: Results from a Phase I Trial of Atezolizumab , 2019, Clinical Cancer Research.
[48] M. Eckstein,et al. New insights in predictive determinants of the tumor immune microenvironment for immune checkpoint inhibition: a never ending story? , 2019, Annals of translational medicine.
[49] G. Bakker,et al. The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture , 2019, bioRxiv.
[50] R. Zeiser,et al. Clinical implications of tumor-intrinsic mechanisms regulating PD-L1 , 2019, Science Translational Medicine.
[51] P. Forde,et al. PD-1 Blockade in Early-Stage Lung Cancer. , 2019, Annual review of medicine.
[52] R. Najafi,et al. PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy , 2018, Journal of cellular physiology.
[53] P. Boya,et al. Lysosomal membrane permeabilization and cell death , 2018, Traffic.
[54] F. Treussart,et al. Fluorescent Nanodiamond Applications for Cellular Process Sensing and Cell Tracking , 2018, Micromachines.
[55] J. Rossjohn,et al. Unconventional T Cell Targets for Cancer Immunotherapy. , 2018, Immunity.
[56] T. Schumacher,et al. Regulation and Function of the PD-L1 Checkpoint. , 2018, Immunity.
[57] S. Lipton,et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 , 2018, Cell Death & Differentiation.
[58] S. Lipton,et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 , 2018, Cell Death & Differentiation.
[59] K. Zak,et al. Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2. , 2017, Structure.
[60] T. Fu,et al. Expression levels of cleaved caspase-3 and caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma , 2017, PloS one.
[61] N. Prabhakar,et al. Intracellular Trafficking of Fluorescent Nanodiamonds and Regulation of Their Cellular Toxicity , 2017, ACS omega.
[62] A. Goodman,et al. PD-1–PD-L1 immune-checkpoint blockade in B-cell lymphomas , 2017, Nature Reviews Clinical Oncology.
[63] K. He,et al. FDA Approval Summary: Accelerated Approval of Pembrolizumab for Second-Line Treatment of Metastatic Melanoma , 2017, Clinical Cancer Research.
[64] J. Wargo,et al. Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy , 2017, Cell.
[65] Huanyu Chen,et al. FDA Approval Summary: Pembrolizumab for the Treatment of Patients with Unresectable or Metastatic Melanoma , 2017, Clinical Cancer Research.
[66] P. Keegan,et al. U.S. FDA Approval Summary: Nivolumab for Treatment of Unresectable or Metastatic Melanoma Following Progression on Ipilimumab , 2017, Clinical Cancer Research.
[67] R. Scolyer,et al. Resistance to PD1/PDL1 checkpoint inhibition. , 2017, Cancer treatment reviews.
[68] K. Zak,et al. Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1) , 2016, Oncotarget.
[69] M. Vicente-Manzanares. Faculty of 1000 evaluation for Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma. , 2016 .
[70] A. P. Bell,et al. Proinflammatory Effects of Pyrogenic and Precipitated Amorphous Silica Nanoparticles in Innate Immunity Cells. , 2016, Toxicological sciences : an official journal of the Society of Toxicology.
[71] B. Dörken,et al. Myeloid-derived suppressor cells in human peripheral blood: Optimized quantification in healthy donors and patients with metastatic renal cell carcinoma. , 2015, Immunology letters.
[72] Lu Tian,et al. Nanodiamond-conjugated transferrin as chemotherapeutic drug delivery , 2015 .
[73] David M. Woods,et al. HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade , 2015, Cancer Immunology Research.
[74] J. Schlom,et al. PD-1 and PD-L1 expression on PBMC subsets in normal individuals and cancer patients , 2014, Journal of Immunotherapy for Cancer.
[75] M. Delorenzi,et al. Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy , 2014, Nature Medicine.
[76] David C. Smith,et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[77] Haijun Yu,et al. Nanodiamonds-mediated doxorubicin nuclear delivery to inhibit lung metastasis of breast cancer. , 2013, Biomaterials.
[78] Giuseppe Schettino,et al. Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures , 2013, PloS one.
[79] Antoni Ribas,et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. , 2013, The New England journal of medicine.
[80] Dongxin Wang,et al. PEGylated nanodiamond for chemotherapeutic drug delivery , 2013 .
[81] David R McIlwain,et al. Caspase functions in cell death and disease. , 2013, Cold Spring Harbor perspectives in biology.
[82] A. Prina‐Mello,et al. Citrullination as early-stage indicator of cell response to Single-Walled Carbon Nanotubes , 2013, Scientific Reports.
[83] D. Firsanov,et al. Dynamics of γH2AX formation and elimination in mammalian cells after X-irradiation. , 2012, Biochimie.
[84] H. Man,et al. Diamond as a nanomedical agent for versatile applications in drug delivery, imaging, and sensing , 2012 .
[85] E. Mardis,et al. Cancer Exome Analysis Reveals a T Cell Dependent Mechanism of Cancer Immunoediting , 2012, Nature.
[86] C. Drake,et al. Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma , 2011, Clinical Cancer Research.
[87] Shengbing Huang,et al. The Role of Autophagy in Cancer: Therapeutic Implications , 2011, Molecular Cancer Therapeutics.
[88] Dermot Kelleher,et al. Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity , 2011, Journal of nanobiotechnology.
[89] K. O'Byrne,et al. Receptor tyrosine kinases and their activation in melanoma , 2011, Pigment cell & melanoma research.
[90] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[91] H. Chung,et al. Nanomaterials for cancer therapy and imaging , 2011, Molecules and cells.
[92] A. Korman,et al. Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy. , 2010, Seminars in oncology.
[93] G. Kroemer,et al. Lysosomal membrane permeabilization in cell death , 2008, Oncogene.
[94] Chenjie Xu,et al. Controlled PEGylation of Monodisperse Fe3O4 Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells , 2007 .
[95] V. Natale,et al. H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[96] G. Collins. The next generation. , 2006, Scientific American.
[97] E. Rogakou,et al. Quantitative Detection of 125IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody , 2002 .
[98] R. Hendrick. Review of clinical trials , 2002, Breast Cancer Research.
[99] E. Rogakou,et al. Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody. , 2002, Radiation research.
[100] Jennifer L. Dornan. Past , Present , and Future Directions , 2002 .
[101] R. Schreiber,et al. Eradication of established tumors by CD8+ T cell adoptive immunotherapy. , 2000, Immunity.
[102] K. Öllinger,et al. Cellular injury induced by oxidative stress is mediated through lysosomal damage. , 1995, Free radical biology & medicine.
[103] E. Montserrat. [The never ending story]. , 1995, Medicina clinica.
[104] E Griffiths,et al. Cell killing by lysosomotropic detergents , 1983, The Journal of cell biology.