Doppler calibration method for Spectral Domain OCT spectrometers

We present a calibration method for SD-OCT domain spectrometers based on the M-scan of a moving mirror. This method allows determination of the wavenumber sampling increment which determines the depth axis assigned to the structural image. It also allows wavelength calibration of individual pixels which ensures correct re-sampling prior to Fast Fourier Transform. Determination of the spectrometer resolution, which determines sensitivity and resolution decay with depth, is also possible. The wavelength calibration results suggest that hardware calibration of the spectrometers is a necessary complement to the computational methods presented here.

[1]  Ton G van Leeuwen,et al.  Oxygen saturation-dependent absorption and scattering of blood. , 2004, Physical review letters.

[2]  Barry Cense,et al.  Autocalibration of spectral-domain optical coherence tomography spectrometers for in vivo quantitative retinal nerve fiber layer birefringence determination. , 2007, Journal of biomedical optics.

[3]  S H Yun,et al.  Motion artifacts in optical coherence tomography with frequency-domain ranging. , 2004, Optics express.

[4]  Dirk J. Faber,et al.  Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography. , 2005 .

[5]  Dirk J. Faber,et al.  Recent developments in optical coherence tomography for imaging the retina , 2007, Progress in Retinal and Eye Research.

[6]  T. Yatagai,et al.  Simultaneous B-M-mode scanning method for real-time full-range Fourier domain optical coherence tomography. , 2006, Applied optics.

[7]  Zhiqiang Xu,et al.  A zero-crossing detection method applied to Doppler OCT. , 2008, Optics express.

[8]  P. Serruys,et al.  Optical Coherence Tomography in Cardiovascular Research , 2007 .

[9]  Maciej Wojtkowski,et al.  Complex spectral interferometry OCT , 1998, European Conference on Biomedical Optics.

[10]  Zhilin Hu,et al.  Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer. , 2007, Optics letters.

[11]  C. Dorrer,et al.  Spectral resolution and sampling issues in Fourier-transform spectral interferometry , 2000 .

[12]  A. Fercher,et al.  Performance of fourier domain vs. time domain optical coherence tomography. , 2003, Optics express.

[13]  J. Duker,et al.  Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation. , 2004, Optics express.

[14]  S. Yun,et al.  High-speed spectral-domain optical coherence tomography at 1.3 mum wavelength. , 2003, Optics express.

[15]  R. Leitgeb,et al.  Resonant Doppler flow imaging and optical vivisection of retinal blood vessels. , 2007, Optics express.

[16]  Dirk Faber,et al.  Comparative optical coherence tomography imaging of human esophagus: how accurate is localization of the muscularis mucosae? , 2002, Gastrointestinal endoscopy.

[17]  Ruikang K. Wang.  In vivo full range complex Fourier domain optical coherence tomography , 2007 .

[18]  V. M. Kodach,et al.  Wavelength swept Ti: sapphire laser , 2008 .