Why Life Oscillates - Biological Rhythms and Health

A multitude of biological rhythms have been identified in the whole organism as well as within each living cell. Some of these rhythms reflect adaptations to our environment, while others run on their own. Recent evidence shows that these rhythms and their interaction might be more important not only for recreation but also for our health. Disturbance of the circadian rhythms by jet lag or shift work not only disturbs our metabolic balance but also increases the incidence of cancer. Rhythms in the organism obviously stabilize systemic functions: They increase organismic stability by calibrating the system's characteristics. Regulation curves in time and space are crucial for controlling physiological long-term stability. To be continuously aware of its properties an autopetic system may vary its parameters slightly over several time scales at different frequencies¿akin to what our body does, e.g. in heart-rate variability.

[1]  Terrence J. Sejnowski,et al.  Biological Clocks Coordinately Keep Life on Time , 2005, Science.

[2]  Chris Arney Sync: The Emerging Science of Spontaneous Order , 2007 .

[3]  D. Cardinali,et al.  Melatonin as a Time-Meaningful Signal in Circadian Organization of Immune Response , 1999, Neurosignals.

[4]  L. Partridge,et al.  Counting the calories: the role of specific nutrients in extension of life span by food restriction. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.

[5]  K. Mokbel,et al.  The evolving role of the dynamic thermal analysis in the early detection of breast cancer , 2005, International seminars in surgical oncology : ISSO.

[6]  H G Zapotoczky,et al.  Increased heart rate in depressed subjects in spite of unchanged autonomic balance? , 1998, Journal of affective disorders.

[7]  J. O'donnell Insomnia in cancer patients. , 2004, Clinical cornerstone.

[8]  P Lavie,et al.  Sleep-wake as a biological rhythm. , 2001, Annual review of psychology.

[9]  I. Edery,et al.  Circadian rhythms in a nutshell. , 2000, Physiological genomics.

[10]  S. Rivkees Developing circadian rhythmicity in infants. , 2003, Pediatrics.

[11]  H. Bettermann,et al.  Heart rate dynamics and cardiorespiratory coordination in diabetic and breast cancer patients. , 2001, Clinical physiology.

[12]  Patrick Y Lee,et al.  The dynamic range of biologic functions and variation of many environmental cues may be declining in the modern age: implications for diseases and therapeutics. , 2005, Medical hypotheses.

[13]  O. Pourquié The Segmentation Clock: Converting Embryonic Time into Spatial Pattern , 2003, Science.

[14]  Denis Duboule,et al.  Time for Chronomics? , 2003, Science.

[15]  C. Graff,et al.  Synchronization of the Molecular Clockwork by Light- and Food-Related Cues in Mammals , 2003, Biological chemistry.

[16]  K. Aihara,et al.  Molecular communication through stochastic synchronization induced by extracellular fluctuations. , 2005, Physical review letters.

[17]  R. Kronauer,et al.  Nonphotic entrainment of the human circadian pacemaker. , 1998, The American journal of physiology.

[18]  Richard G. Stevens,et al.  Cancer and Rhythm , 2006, Cancer Causes & Control.

[19]  K. Mokbel Breast cancer prevention. , 2002, The British journal of general practice : the journal of the Royal College of General Practitioners.

[20]  D. Cardinali,et al.  Melatonin in sleep disorders and jet-lag. , 2002, Neuro endocrinology letters.

[21]  Sung Ping Law The Regulation of Menstrual Cycle and its Relationship to the Moon , 1986, Acta obstetricia et gynecologica Scandinavica.

[22]  A. Winfree The geometry of biological time , 1991 .

[23]  H. Lackner,et al.  Oscillations of heart rate and respiration synchronize during poetry recitation. , 2004, American journal of physiology. Heart and circulatory physiology.

[24]  G. Cornelissen,et al.  Associations by signatures and coherences between the human circulation and helio- and geomagnetic activity. , 2000, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[25]  Richard E Kronauer,et al.  Temporal dynamics of late-night photic stimulation of the human circadian timing system. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

[26]  L. Fu,et al.  The circadian clock: pacemaker and tumour suppressor , 2003, Nature Reviews Cancer.

[27]  Ian Gross,et al.  Rest-activity patterns of premature infants are regulated by cycled lighting. , 2004, Pediatrics.

[28]  Giuseppe Tonini,et al.  Cancer chronotherapy: Principles, applications, and perspectives , 2003, Cancer.

[29]  W J Hrushesky,et al.  The respiratory sinus arrhythmia: a measure of cardiac age. , 1984, Science.

[30]  H. Bartsch,et al.  The Anti-tumor Activity of Pineal Melatonin and Cancer Enhancing Life Styles in Industrialized Societies , 2006, Cancer Causes & Control.

[31]  M. Belyea,et al.  Preterm infants born at less than 31 weeks' gestation have improved growth in cycled light compared with continuous near darkness. , 2002, The Journal of pediatrics.

[32]  Edward J Masoro,et al.  Subfield history: caloric restriction, slowing aging, and extending life. , 2003, Science of aging knowledge environment : SAGE KE.

[33]  G. Preti,et al.  Lunar influences on the reproductive cycle in women. , 1987, Human biology.

[34]  Rakesh K Jain,et al.  Molecular regulation of vessel maturation , 2003, Nature Medicine.

[35]  A. Kudlicki,et al.  Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes , 2005, Science.

[36]  S. Kay,et al.  Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. , 2000, Science.

[37]  Thomas Kenner,et al.  Phase‐ and frequency coordination of cardiac and respiratory function , 1995 .

[38]  H G Zapotoczky,et al.  Heart Rate Variability as a Prognostic Tool in Cardiology: A Contribution to the Problem From a Theoretical Point of View , 1994, Circulation.

[39]  W. Cutler Lunar and menstrual phase locking. , 1980, American journal of obstetrics and gynecology.

[40]  Sonia Cortassa,et al.  Why Homeodynamics, Not Homeostasis? , 2001, TheScientificWorldJournal.

[41]  L. Wetterberg,et al.  Urinary melatonin levels in human breast cancer patients , 2005, Journal of Neural Transmission.

[42]  M Laguens,et al.  Circadian rhythm chaos: a new breast cancer marker. , 2001, International journal of fertility and women's medicine.