Medical Lessons Learned From Chernobyl Relative to Nuclear Detonations and Failed Nuclear Reactors

The Chernobyl disaster in 1986 involved the largest airborne release of radioactivity in history, more than 100 times as much radioactivity as the Hiroshima and Nagasaki atomic bombs together. The resulting emergency response, administrative blunders, and subsequent patient outcomes from this large-scale radiological disaster provide a wealth of information and valuable lessons for those who may find themselves having to deal with the staggering consequences of nuclear war. Research findings, administrative strategies (successful and otherwise), and resulting clinical procedures from the Chernobyl experience are reviewed to determine a current utility in addressing the appropriate protocols for a medical response to nuclear war. As various myths are still widely associated with radiation exposure, attention is given to the realities of a mass casualty medical response as it would occur with a nuclear detonation.

[1]  A. Nyagu,et al.  Psychophysiologic aftereffects of prenatal irradiation. , 1998, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[2]  A. V. Nesterenko,et al.  Reducing the 137Cs-load in the organism of "Chernobyl" children with apple-pectin. , 2004, Swiss medical weekly.

[3]  G. Howe LEUKEMIA FOLLOWING THE CHERNOBYL ACCIDENT , 2007, Health physics.

[4]  L. Knudsen Legally induced abortions in Denmark after Chernobyl. , 1991, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[5]  K. Moysich,et al.  Chernobyl-related ionising radiation exposure and cancer risk: an epidemiological review. , 2002, The Lancet. Oncology.

[6]  D. Reisfeld,et al.  Neurobehavioral and cognitive performances of children exposed to low-dose radiation in the Chernobyl accident: the Israeli Chernobyl Health Effects Study. , 2004, American journal of epidemiology.

[7]  J. Schlom,et al.  Phase I trial of iodine-131-chimeric B72.3 (human IgG4) in metastatic colorectal cancer. , 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[8]  R. T. Lie,et al.  Pregnancy outcome in Norway after Chernobyl. , 1991, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[9]  N. Orlova,et al.  Female reproductive function in areas affected by radiation after the Chernobyl power station accident , 1993, Environmental health perspectives.

[10]  Dillwyn Williams,et al.  Chernobyl and the future: Too soon for a final diagnosis , 2006, Nature.

[11]  A. Spinelli,et al.  The effects of the Chernobyl explosion on induced abortion in Italy. , 1991, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[12]  B. Modan,et al.  Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. 1995. , 2012, Radiation research.

[13]  Stephen V Musolino,et al.  EMERGENCY RESPONSE GUIDANCE FOR THE FIRST 48 HOURS AFTER THE OUTDOOR DETONATION OF AN EXPLOSIVE RADIOLOGICAL DISPERSAL DEVICE , 2006, Health physics.

[14]  Cham E Dallas,et al.  Prediction Modeling to Determine the Adequacy of Medical Response to Urban Nuclear Attack , 2007, Disaster Medicine and Public Health Preparedness.

[15]  L. Hennen,et al.  The influence of extracorporeal clearance techniques on elimination of radiocesium after internal contamination. , 1995, Health physics.

[16]  C. Kruger,et al.  The Information Infrastructure of Toxicology , 2007 .

[17]  Communicating risk to the public after radiological incidents , 2007, BMJ : British Medical Journal.

[18]  R. Platzman,et al.  What is ionizing radiation? , 1959, Scientific American.

[19]  C. Proukakis,et al.  The victims of chernobyl in Greece: induced abortions after the accident. , 1987, British medical journal.

[20]  C. Fullerton,et al.  The threat of biological weapons. Prophylaxis and mitigation of psychological and social consequences. , 1997, JAMA.

[21]  A. Czeizel Incidence of legal abortions and congenital abnormalities in Hungary. , 1991, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[22]  V. Drozdovitch,et al.  The psychological development of children from Belarus exposed in the prenatal period to radiation from the Chernobyl atomic power plant. , 1999, Journal of child psychology and psychiatry, and allied disciplines.

[23]  D. Flynn,et al.  Nuclear terrorism: triage and medical management of radiation and combined-injury casualties. , 2006, The Surgical clinics of North America.

[24]  E. Bromet,et al.  School and neuropsychological performance of evacuated children in Kyiv 11 years after the Chornobyl disaster. , 2000, Journal of child psychology and psychiatry, and allied disciplines.

[25]  Zhores A. Medvedev,et al.  The legacy of Chernobyl , 1990 .

[26]  F. Castronovo Teratogen update: radiation and Chernobyl. , 1999, Teratology.

[27]  D Williams,et al.  Radiation carcinogenesis: lessons from Chernobyl , 2008, Oncogene.

[28]  H. Dolk,et al.  Evaluation of the impact of Chernobyl on the prevalence of congenital anomalies in 16 regions of Europe. EUROCAT Working Group. , 1999, International journal of epidemiology.

[29]  A. Yablokov 5. Nonmalignant diseases after the Chernobyl catastrophe. , 2009, Annals of the New York Academy of Sciences.

[30]  A. Auvinen,et al.  Cancer consequences of the Chernobyl accident in Europe outside the former USSR: A review , 1996, International journal of cancer.