Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype

[1]  R. Paus,et al.  Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation. , 2007, The Journal of investigative dermatology.

[2]  S. Steinberg,et al.  Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. , 2007, Cancer research.

[3]  P. Steeg.  Tumor metastasis: mechanistic insights and clinical challenges , 2006, Nature Medicine.

[4]  H. Mehdorn,et al.  Differential Expression of Matrix Metalloproteinases in Brain- and Bone-Seeking Clones of Metastatic MDA-MB-231 Breast Cancer Cells , 2006, Journal of Neuro-Oncology.

[5]  Alissa M. Weaver.  Invadopodia: Specialized Cell Structures for Cancer Invasion , 2006, Clinical & Experimental Metastasis.

[6]  C. Bucana,et al.  Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

[7]  K. Neurath,et al.  Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation , 2006, Oncogene.

[8]  R. Weil,et al.  Breast cancer metastasis to the central nervous system. , 2005, The American journal of pathology.

[9]  K. Reiss,et al.  Enhanced expression and shedding of the transmembrane chemokine CXCL16 by reactive astrocytes and glioma cells , 2005, Journal of neurochemistry.

[10]  M. Marra,et al.  Differential expression and cytoplasm/membrane distribution of endoglin (CD105) in human tumour cell lines: Implications in the modulation of cell proliferation. , 2005, International journal of oncology.

[11]  H. Mehdorn,et al.  Surgical treatment for brain metastases: prognostic factors and survival in 177 patients , 2005, Neurosurgical Review.

[12]  A. Theocharis,et al.  Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential. , 2004, Anticancer research.

[13]  H. Mehdorn,et al.  Functional Significance of Vascular Endothelial Growth Factor Receptor Expression on Human Glioma Cells , 2004, Journal of Neuro-Oncology.

[14]  M. Maio,et al.  Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels , 2003, Oncogene.

[15]  H. Mehdorn,et al.  Interaction of transforming growth factor-β (TGF-β) and epidermal growth factor (EGF) in human glioma cells , 2003, Journal of Neuro-Oncology.

[16]  I. Fidler,et al.  The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited , 2003, Nature Reviews Cancer.

[17]  P. Friedl,et al.  Tumour-cell invasion and migration: diversity and escape mechanisms , 2003, Nature Reviews Cancer.

[18]  R. Lucius,et al.  Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells , 2002, Journal of Neuroimmunology.

[19]  J. Laissue,et al.  MMP‐19: cellular localization of a novel metalloproteinase within normal breast tissue and mammary gland tumours , 2001, The Journal of pathology.

[20]  Paul J. Williams,et al.  A Bone‐Seeking Clone Exhibits Different Biological Properties from the MDA‐MB‐231 Parental Human Breast Cancer Cells and a Brain‐Seeking Clone In Vivo and In Vitro , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[21]  M. Maio,et al.  Endoglin: An accessory component of the TGF‐β‐binding receptor‐complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies , 2001, Journal of cellular physiology.

[22]  D. Thomas,et al.  An invasion-related complex of cortactin, paxillin and PKCμ associates with invadopodia at sites of extracellular matrix degradation , 1999, Oncogene.

[23]  J. Martín-Pérez,et al.  Phosphorylation of the human-transforming-growth-factor-beta-binding protein endoglin. , 1994, The Biochemical journal.

[24]  D. Muller,et al.  A simple method for organotypic cultures of nervous tissue , 1991, Journal of Neuroscience Methods.

[25]  M. Letarte,et al.  Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells. , 1990, The Journal of biological chemistry.

[26]  A. Mazar,et al.  The urokinase plasminogen activator system in cancer: Implications for tumor angiogenesis and metastasis , 2004, Angiogenesis.