Diagnostic potential of breath analysis--focus on volatile organic compounds.

[1]  P. Španěl,et al.  Selected ion flow tube: a technique for quantitative trace gas analysis of air and breath , 1996, Medical and Biological Engineering and Computing.

[2]  Bradford G. Stone,et al.  Effect of regulating cholesterol biosynthesis on breath isoprene excretion in men , 1993, Lipids.

[3]  Terence H Risby,et al.  Effects of ventilation on the collection of exhaled breath in humans. , 2004, Journal of applied physiology.

[4]  W. Pollock,et al.  Bacteria produce the volatile hydrocarbon isoprene , 1995, Current Microbiology.

[5]  E. Martinelli,et al.  Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors. , 2003, Biosensors & bioelectronics.

[6]  P. Clarkson,et al.  Oxidative stress, exercise, and antioxidant supplementation. , 2003, Toxicology.

[7]  T. Mitsui,et al.  Inadequacy of theoretical basis of breath methylated alkane contour for assessing oxidative stress. , 2003, Clinica chimica acta; international journal of clinical chemistry.

[8]  Claudio Ronco,et al.  Breath ethane in dialysis patients and control subjects. , 2003, Free radical biology & medicine.

[9]  M. Phillips,et al.  Response: scientific basis of the breath methylated alkane contour , 2003 .

[10]  Kevin Gleeson,et al.  Detection of lung cancer with volatile markers in the breath. , 2003, Chest.

[11]  M. Phillips,et al.  Breath markers of oxidative stress in patients with unstable angina. , 2003, Heart disease.

[12]  M. Phillips,et al.  Increased oxidative stress in younger as well as in older humans. , 2003, Clinica chimica acta; international journal of clinical chemistry.

[13]  H. Steinhart,et al.  Antioxidant Vitamin Supplementation in Crohn's Disease Decreases Oxidative Stress: A Randomized Controlled Trial , 2003, American Journal of Gastroenterology.

[14]  F. Ricciardolo,et al.  Multiple roles of nitric oxide in the airways , 2003, Thorax.

[15]  M. Phillips,et al.  Effect of oxygen on breath markers of oxidative stress , 2003, European Respiratory Journal.

[16]  Marco Alessandrini,et al.  A novel method for diagnosing chronic rhinosinusitis based on an electronic nose. , 2003, Anales otorrinolaringologicos ibero-americanos.

[17]  J. Pawliszyn,et al.  Breath analysis and monitoring by membrane extraction with sorbent interface. , 2002, Analytical chemistry.

[18]  K. Torén,et al.  Determination of ethane, pentane and isoprene in exhaled air using a multi-bed adsorbent and end-cut gas-solid chromatography. , 2002, The Analyst.

[19]  M. Gare,et al.  Dilution of respiratory solutes in exhaled condensates. , 2002, American journal of respiratory and critical care medicine.

[20]  W. Miekisch,et al.  Breath Markers and Soluble Lipid Peroxidation Markers in Critically Ill Patients , 2002, Clinical chemistry and laboratory medicine.

[21]  P. Barnes,et al.  Biomarkers of some pulmonary diseases in exhaled breath , 2002, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[22]  M. Pelli,et al.  Lack of Isoprene Overproduction during Peritoneal Dialysis , 2002, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

[23]  Terence H Risby,et al.  Breath biomarkers for detection of human liver diseases: preliminary study , 2002, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[24]  N. Levin,et al.  Oxidative stress and inflammation in hemodialysis patients. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[25]  A. Choi,et al.  Exhaled monoxides as a pulmonary function test: use of exhaled nitric oxide and carbon monoxide. , 2001, Clinics in chest medicine.

[26]  J. Orens,et al.  Patterns and significance of exhaled-breath biomarkers in lung transplant recipients with acute allograft rejection. , 2001, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[27]  McGrath Lawrence T.,et al.  Breath isoprene in patients with heart failure , 2001 .

[28]  D. B. Milligan,et al.  Real time analysis of breath volatiles using SIFT-MS in cigarette smoking , 2001, Redox report : communications in free radical research.

[29]  P. Hering,et al.  Real-time monitoring of ethane in human breath using mid-infrared cavity leak-out spectroscopy , 2001 .

[30]  K. Geiger,et al.  Analysis of volatile disease markers in blood. , 2001, Clinical chemistry.

[31]  M. Timio,et al.  Onset, Time Course, and Persistence of Increased Haemodialysis-Induced Breath Isoprene Emission , 2001, Nephron.

[32]  D. Yates,et al.  Role of exhaled nitric oxide in asthma , 2001, Immunology and cell biology.

[33]  P. Španěl,et al.  A new 'online' method to measure increased exhaled isoprene in end-stage renal failure. , 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[34]  Josef Guttmann,et al.  CO2-controlled sampling of alveolar gas in mechanically ventilated patients , 2001 .

[35]  L. T. McGrath,et al.  Breath isoprene during acute respiratory exacerbation in cystic fibrosis. , 2000, The European respiratory journal.

[36]  T. Risby,et al.  Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis. , 2000, Gastroenterology.

[37]  P. Gibson,et al.  Noninvasive assessment of airway inflammation in children: induced sputum, exhaled nitric oxide, and breath condensate. , 2000, The European respiratory journal.

[38]  P. Barnes,et al.  Elevation of exhaled ethane concentration in asthma. , 2000, American journal of respiratory and critical care medicine.

[39]  K. Naitoh,et al.  Is endogenous isoprene the only coeluting compound in the measurement of breath pentane? , 2000, Clinica chimica acta; international journal of clinical chemistry.

[40]  P. Barnes,et al.  Exhaled ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[41]  P. Shah,et al.  Exhaled ethane is elevated in cystic fibrosis and correlates with carbon monoxide levels and airway obstruction. , 2000, American journal of respiratory and critical care medicine.

[42]  D. B. Milligan,et al.  Quantitative analysis of trace gases of breath during exercise using the new SIFT–MS technique , 2000, Redox report : communications in free radical research.

[43]  J. Allard,et al.  Breath alkanes as a marker of oxidative stress in different clinical conditions. , 2000, Free radical biology & medicine.

[44]  T. Risby,et al.  Clinical application of breath biomarkers of oxidative stress status. , 1999, Free radical biology & medicine.

[45]  P. Španěl,et al.  Trace gases in breath of healthy volunteers when fasting and after a protein-calorie meal: a preliminary study. , 1999, Journal of applied physiology.

[46]  S. Davies,et al.  Quantification of breath isoprene using the selected ion flow tube mass spectrometric analytical method. , 1999, Rapid communications in mass spectrometry : RCM.

[47]  Mario Timio,et al.  Volatile Alkanes and Increased Concentrations of Isoprene in Exhaled Air during Hemodialysis , 1999, Nephron.

[48]  M. Phillips,et al.  Variation in volatile organic compounds in the breath of normal humans. , 1999, Journal of chromatography. B, Biomedical sciences and applications.

[49]  R. Cataneo,et al.  Volatile organic compounds in breath as markers of lung cancer: a cross-sectional study , 1999, The Lancet.

[50]  J. Guttmann,et al.  In vivo evaluation of a new method for chemical analysis of volatile components in the respiratory gas of mechanically ventilated patients. , 1999, Technology and health care : official journal of the European Society for Engineering and Medicine.

[51]  G B Bulkley,et al.  Ethane: a marker of lipid peroxidation during cardiopulmonary bypass in humans. , 1999, Free radical biology & medicine.

[52]  L. Appel,et al.  Effect of dietary patterns on measures of lipid peroxidation: results from a randomized clinical trial. , 1998, Circulation.

[53]  J. Schubert,et al.  Method for analysis of exhaled air by microwave energy desorption coupled with gas chromatography-flame ionization detection-mass spectrometry. , 1998, Journal of chromatography. B, Biomedical sciences and applications.

[54]  Johnny Ludvigsson,et al.  Exhaled Isoprene and Acetone in Newborn Infants and in Children with Diabetes Mellitus , 1998, Pediatric Research.

[55]  J. Schubert,et al.  Application of a new method for analysis of exhaled gas in critically ill patients , 1998, Intensive Care Medicine.

[56]  Gustafsson Le.  Exhaled nitric oxide as a marker in asthma. , 1998 .

[57]  T. Barstow,et al.  The effect of exercise intensity on lipid peroxidation. , 1997, Medicine and science in sports and exercise.

[58]  P. Španěl,et al.  Quantitative analysis of ammonia on the breath of patients in end-stage renal failure. , 1997, Kidney international.

[59]  P. Scheff,et al.  Exhaled pentane and nitric oxide levels in patients with obstructive sleep apnea. , 1997, Chest.

[60]  M. Phillips.  Method for the collection and assay of volatile organic compounds in breath. , 1997, Analytical biochemistry.

[61]  J D Pleil,et al.  Exhaled human breath measurement method for assessing exposure to halogenated volatile organic compounds. , 1997, Clinical chemistry.

[62]  C. Olopade,et al.  Exhaled pentane levels in acute asthma. , 1997, Chest.

[63]  Y. D. Kim,et al.  Breath pentane concentrations during labor and the effect of epidural analgesia on the pentane concentration. , 1997, International journal of obstetric anesthesia.

[64]  J. Pawliszyn,et al.  Solid-phase microextraction for the analysis of human breath. , 1997, Analytical chemistry.

[65]  M D Knutson,et al.  Concentrating breath samples using liquid nitrogen: a reliable method for the simultaneous determination of ethane and pentane. , 1996, Analytical biochemistry.

[66]  H. Garewal,et al.  Exhaled ethane and antioxidant vitamin supplements in active smokers. , 1996, Chest.

[67]  T. Risby,et al.  Breath isoprene: temporal changes in respiratory output after exposure to ozone. , 1996, Journal of applied physiology.

[68]  Breath pentane and plasma lipid peroxides in ischemic heart disease. , 1995, Free radical biology & medicine.

[69]  P. Sobotka,et al.  Expired hydrocarbons in patients with acute myocardial infarction. , 1995, Free radical research.

[70]  R. Fall,et al.  Characterization of Aspen Isoprene Synthase, an Enzyme Responsible for Leaf Isoprene Emission to the Atmosphere (*) , 1995, The Journal of Biological Chemistry.

[71]  H. Garewal,et al.  Cigarette smoking and ethane exhalation in humans. , 1995, American journal of respiratory and critical care medicine.

[72]  M. Phillips,et al.  Volatile organic compounds in the breath of patients with schizophrenia. , 1995, Journal of clinical pathology.

[73]  J. Pleil,et al.  Measurement of volatile organic compounds in exhaled breath as collected in evacuated electropolished canisters. , 1995, Journal of chromatography. B, Biomedical applications.

[74]  R. Abrams,et al.  Breath ethane generation during clinical total body irradiation as a marker of oxygen-free-radical-mediated lipid peroxidation: a case study. , 1994, Free radical biology & medicine.

[75]  J. Ramsey,et al.  Breath pentane and heart rejection. , 1994, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[76]  K. Pickard,et al.  The regulation of transaminative flux of methionine in rat liver mitochondria. , 1994, Archives of biochemistry and biophysics.

[77]  C. Kneepkens,et al.  The potential of the hydrocarbon breath test as a measure of lipid peroxidation. , 1994, Free radical biology & medicine.

[78]  J. Springfield,et al.  Pitfalls in the use of breath pentane measurements to assess lipid peroxidation. , 1994, Journal of lipid research.

[79]  Sobotka Pa,et al.  Breath pentane is a marker of acute cardiac allograft rejection. , 1994 .

[80]  T. Risby,et al.  Visceral lipid peroxidation occurs at reperfusion after supraceliac aortic cross-clamping. , 1994, Journal of vascular surgery.

[81]  P. Sobotka,et al.  Elevated breath pentane in heart failure reduced by free radical scavenger. , 1993, Free radical biology & medicine.

[82]  A. Cailleux,et al.  Decrease of isoprene concentrations in blood during general anesthesia. , 1993, Biochemical medicine and metabolic biology.

[83]  R. Nelson,et al.  Determination of inflammatory bowel disease activity by breath pentane analysis , 1993, Diseases of the colon and rectum.

[84]  D. Kohlmüller,et al.  Is n-pentane really an index of lipid peroxidation in humans and animals? A methodological reevaluation. , 1993, Analytical biochemistry.

[85]  T. Risby,et al.  Breath ethane: a specific indicator of free-radical-mediated lipid peroxidation following reperfusion of the ischemic liver. , 1992, Free radical biology & medicine.

[86]  A. Cailleux,et al.  Blood isoprene concentrations in humans and in some animal species. , 1992, Biochemical medicine and metabolic biology.

[87]  M. Phillips,et al.  Ion-trap detection of volatile organic compounds in alveolar breath. , 1992, Clinical chemistry.

[88]  P. Sobotka,et al.  High breath pentane concentrations during acute myocardial infarction , 1991, The Lancet.

[89]  A. Cailleux,et al.  Isoprene and sleep. , 1989, Life sciences.

[90]  A. Van Gossum,et al.  Plasma vitamin E and selenium and breath pentane in home parenteral nutrition patients. , 1988, The American journal of clinical nutrition.

[91]  A. Gossum,et al.  Decrease in lipid peroxidation measured by breath pentane output in normals after oral supplementation with vitamin E , 1988 .

[92]  T. Ludden,et al.  The pharmacokinetics of pentane, a by-product of lipid peroxidation. , 1987, Drug metabolism and disposition: the biological fate of chemicals.

[93]  R. Abeles,et al.  Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. , 1986, Biochemistry.

[94]  A. Tangerman,et al.  New methods for the release of volatile sulfur compounds from human serum: its determination by Tenax trapping and gas chromatography and its application in liver diseases. , 1985, The Journal of laboratory and clinical medicine.

[95]  J. Mead,et al.  Acid-catalyzed formation of isoprene from a mevalonate-derived product using a rat liver cytosolic fraction. , 1985, The Journal of biological chemistry.

[96]  J. Mead,et al.  In vitro biosynthesis of isoprene from mevalonate utilizing a rat liver cytosolic fraction. , 1984, Biochemical and biophysical research communications.

[97]  P. Davis,et al.  Endogenous isopropanol: forensic and biochemical implications. , 1984, Journal of analytical toxicology.

[98]  A. Manolis,et al.  The diagnostic potential of breath analysis. , 1983, Clinical chemistry.

[99]  R. Doty,et al.  Biochemical profile or uremic breath. , 1977, The New England journal of medicine.

[100]  M. Horsmanheimo,et al.  Lung biology in health and disease , 1977 .

[101]  B. Ed,et al.  Biochemistry of Polyisoprenoid Biosynthesis , 1976 .

[102]  J B West,et al.  Measurement of continuous distributions of ventilation-perfusion ratios: theory. , 1974, Journal of applied physiology.

[103]  A. B. Robinson,et al.  Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[104]  L. Zieve,et al.  Mercaptans and dimethyl sulfide in the breath of patients with cirrhosis of the liver. Effect of feeding methionine. , 1970, The Journal of laboratory and clinical medicine.