A flexible and disposable hybrid electrode based on Cu nanowires modified graphene transparent electrode for non-enzymatic glucose sensor

A non-enzymatic glucose sensor based on Cu nanowires (CuNWs) modified graphene transparent electrode (GTE) was developed as a substitute for indium tin oxide (ITO) electrode or glassy carbon electrode (GCE). GTE was prepared by four steps on the polyethylene terephthalate sheet, and then Cu nanowires were deposited onto GTE to achieve the hybrid electrode of CuNWs/GTE by spin-coating. The morphology and phase structures were characterized by scanning electron microscopy and X-ray power diffraction, respectively. The resistance and electrochemical properties of CuNWs/GTE were investigated by four point probe and cyclic voltammetry, respectively. Results indicated that the as-prepared sensor showed higher electrocatalytic activity toward glucose than pristine CuNWs and GTE; The sensor also showed wider linear response for glucose over concentrations ranging from 0.005 to 6.0 mM with a sensitivity of 1100 mu A/(mM cm(2)), low detection limit of 1.6 mu M (S/N = 3), and excellent anti-interference ability. More importantly, the as-prepared sensor had the similar or even better performances compared to those reported on ITO and GCE. (C) 2013 Elsevier Ltd. All rights reserved.

[1]  K. Müllen,et al.  Graphene as Transparent Electrode Material for Organic Electronics , 2011, Advanced materials.

[2]  Graphene-ferroelectric hybrid structure for flexible transparent electrodes. , 2012, ACS nano.

[3]  Liangbing Hu,et al.  Emerging Transparent Electrodes Based on Thin Films of Carbon Nanotubes, Graphene, and Metallic Nanostructures , 2011, Advanced materials.

[4]  Jing Luo,et al.  A novel non-enzymatic glucose sensor based on Cu nanoparticle modified graphene sheets electrode. , 2012, Analytica chimica acta.

[5]  J. Grey,et al.  Production of graphene from graphite oxide using urea as expansion–reduction agent , 2010 .

[6]  P. He,et al.  Zeolite A functionalized with copper nanoparticles and graphene oxide for simultaneous electrochemical determination of dopamine and ascorbic acid. , 2012, Analytica chimica acta.

[7]  Tong Zhang,et al.  A novel non-enzymatic glucose sensor based on NiO hollow spheres , 2013 .

[8]  Liqiang Luo,et al.  Nonenzymatic amperometric determination of glucose by CuO nanocubes-graphene nanocomposite modified electrode. , 2012, Bioelectrochemistry.

[9]  Qinglin Sheng,et al.  A sensitive non-enzymatic glucose sensor in alkaline media based on Cu/MnO2-modified glassy carbon electrode , 2012, Journal of the Iranian Chemical Society.

[10]  Yan Li,et al.  In situ growth of copper nanoparticles on multiwalled carbon nanotubes and their application as non-enzymatic glucose sensor materials , 2010 .

[11]  Xiaoniu Yang,et al.  Improved dispersibility of graphene oxide in o-dichlorobenzene by adding a poly(3-alkylthiophene) , 2012 .

[12]  Hyuck Jung,et al.  A high-performance nonenzymatic glucose sensor made of CuO-SWCNT nanocomposites. , 2013, Biosensors & bioelectronics.

[13]  Tae Seok Seo,et al.  Fabrication of free-standing graphene composite films as electrochemical biosensors , 2011 .

[14]  Benjamin J Wiley,et al.  The Growth Mechanism of Copper Nanowires and Their Properties in Flexible, Transparent Conducting Films , 2010, Advanced materials.

[15]  S. Rhee,et al.  Sub-micrometer-sized graphite as a conducting and catalytic counter electrode for dye-sensitized solar cells. , 2011, ACS applied materials & interfaces.

[16]  Yu Lei,et al.  Ultrasensitive and selective non-enzymatic glucose detection using copper nanowires. , 2012, Biosensors & bioelectronics.

[17]  Z. Stojek,et al.  Nanoparticles and Nanostructured Materials Used in Modification of Electrode Surfaces , 2012 .

[18]  M. Musiani,et al.  Electrodeposition of Cu–Rh alloys and their use as cathodes for nitrate reduction , 2012 .

[19]  R. Ruoff,et al.  Graphene and Graphene Oxide: Synthesis, Properties, and Applications , 2010, Advanced materials.

[20]  Masayoshi Umeno,et al.  Graphene constructed carbon thin films as transparent electrodes for solar cell applications , 2010 .

[21]  Ashok Mulchandani,et al.  Nanowire‐Based Electrochemical Biosensors , 2006 .

[22]  Fabrication of thin-film electrochemical sensors from single-walled carbon nanotubes by vacuum filtration , 2010 .

[23]  Andre K. Geim,et al.  Electric Field Effect in Atomically Thin Carbon Films , 2004, Science.

[24]  Jing Li,et al.  High performance non-enzymatic glucose biosensor based on copper nanowires–carbon nanotubes hybrid for intracellular glucose study , 2013 .

[25]  Sundaram Gunasekaran,et al.  An amperometric non-enzymatic glucose sensor by electrodepositing copper nanocubes onto vertically well-aligned multi-walled carbon nanotube arrays. , 2010, Biosensors & bioelectronics.

[26]  Zichen Wang,et al.  Synthesis, growth mechanism of different Cu nanostructures and their application for non-enzymatic glucose sensing , 2012 .

[27]  Peixiang Cai,et al.  A sensitive nonenzymatic glucose sensor in alkaline media with a copper nanocluster/multiwall carbon nanotube-modified glassy carbon electrode. , 2007, Analytical biochemistry.

[28]  Jia-Wun Wu,et al.  Ionic-liquid-enhanced glucose sensing ability of non-enzymatic Au/graphene electrodes fabricated using supercritical CO₂ fluid. , 2013, Biosensors & bioelectronics.

[29]  R. Ruoff,et al.  Reduced graphene oxide by chemical graphitization. , 2010, Nature communications.

[30]  Hsiu-Mei Lin,et al.  Synthesis of copper nanowire decorated reduced graphene oxide for electro-oxidation of methanol , 2013 .

[31]  E. Kymakis,et al.  Flexible Organic Photovoltaic Cells with In Situ Nonthermal Photoreduction of Spin‐Coated Graphene Oxide Electrodes , 2012, 1208.0988.

[32]  Jianbin Zheng,et al.  A highly sensitive non-enzymatic glucose sensor based on nickel and multi-walled carbon nanotubes nanohybrid films fabricated by one-step co-electrodeposition in ionic liquids , 2012 .

[33]  Wei‐De Zhang,et al.  Fabrication of CuO nanoplatelets for highly sensitive enzyme-free determination of glucose , 2011 .

[34]  Hong-Yan. Yuan,et al.  Improvement of sensitive CuO NFs-ITO nonenzymatic glucose sensor based on in situ electrospun fiber. , 2012, Talanta.

[35]  Hisato Yamaguchi,et al.  Insulator to Semimetal Transition in Graphene Oxide , 2009 .