Grape proanthocyanidin-induced intestinal bloom of Akkermansia muciniphila is dependent on its baseline abundance and precedes activation of host genes related to metabolic health.

[1]  F. Bäckhed,et al.  Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier. , 2018, American journal of physiology. Endocrinology and metabolism.

[2]  J. Meudt,et al.  Effect of Sweetened Dried Cranberry Consumption on Urinary Proteome and Fecal Microbiome in Healthy Human Subjects , 2017, Omics : a journal of integrative biology.

[3]  J. Espín,et al.  The gut microbiota: A key factor in the therapeutic effects of (poly)phenols , 2017, Biochemical pharmacology.

[4]  Weiqing Wang,et al.  Grape seed proanthocyanidin extract ameliorates inflammation and adiposity by modulating gut microbiota in high-fat diet mice. , 2017, Molecular nutrition & food research.

[5]  H. van Loveren,et al.  Safety of cranberry extract powder as a novel food ingredient pursuant to Regulation (EC) No 258/97 , 2017, EFSA journal. European Food Safety Authority.

[6]  M. Xie,et al.  Recovery of dietary fiber and polyphenol from grape juice pomace and evaluation of their functional properties and polyphenol compositions. , 2017, Food & function.

[7]  A. Marette,et al.  A microbial protein that alleviates metabolic syndrome , 2017, Nature Medicine.

[8]  W. D. de Vos,et al.  Comparative genomics and physiology of the butyrate-producing bacterium Intestinimonas butyriciproducens. , 2016, Environmental microbiology reports.

[9]  W. Johnson,et al.  High phenolics Rutgers Scarlet Lettuce improves glucose metabolism in high fat diet-induced obese mice. , 2016, Molecular nutrition & food research.

[10]  T. Shoji,et al.  Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes , 2016, Scientific Reports.

[11]  F. Bäckhed,et al.  From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites , 2016, Cell.

[12]  D. Raoult,et al.  Romboutsia timonensis, a new species isolated from human gut , 2016, New microbes and new infections.

[13]  Shery Jacob,et al.  A simple practice guide for dose conversion between animals and human , 2016, Journal of basic and clinical pharmacy.

[14]  W. D. de Vos,et al.  A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice , 2016, Nature Medicine.

[15]  R. Gomis,et al.  Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice , 2015, Scientific Reports.

[16]  Jens V. Stein,et al.  The outer mucus layer hosts a distinct intestinal microbial niche , 2015, Nature Communications.

[17]  M. Du,et al.  Favourable effects of grape seed extract on intestinal epithelial differentiation and barrier function in IL10-deficient mice , 2015, British Journal of Nutrition.

[18]  Patricio Rojas-Silva,et al.  Dietary Polyphenols Promote Growth of the Gut Bacterium Akkermansia muciniphila and Attenuate High-Fat Diet–Induced Metabolic Syndrome , 2015, Diabetes.

[19]  D. D’Alessio,et al.  Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease. , 2015, Physiological reviews.

[20]  N. Barnich,et al.  Analysis of the σE Regulon in Crohn's Disease-Associated Escherichia coli Revealed Involvement of the waaWVL Operon in Biofilm Formation , 2015, Journal of bacteriology.

[21]  E. Levy,et al.  A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice , 2014, Gut.

[22]  S. Fijan.  Microorganisms with Claimed Probiotic Properties: An Overview of Recent Literature , 2014, International journal of environmental research and public health.

[23]  C. Knauf,et al.  Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics. , 2014, Beneficial microbes.

[24]  Qi-qiang He,et al.  Dietary flavonoids intake and risk of type 2 diabetes: a meta-analysis of prospective cohort studies. , 2014, Clinical nutrition.

[25]  D. van der A,et al.  Dietary Intakes of Individual Flavanols and Flavonols Are Inversely Associated with Incident Type 2 Diabetes in European Populations123 , 2013, The Journal of nutrition.

[26]  Taeko Dohi,et al.  Dysbiosis of Salivary Microbiota in Inflammatory Bowel Disease and Its Association With Oral Immunological Biomarkers , 2013, DNA research : an international journal for rapid publication of reports on genes and genomes.

[27]  I. Raskin,et al.  Concord grape pomace polyphenols complexed to soy protein isolate are stable and hypoglycemic in diabetic mice. , 2013, Journal of agricultural and food chemistry.

[28]  A. Gasbarrini,et al.  Commensal Clostridia: leading players in the maintenance of gut homeostasis , 2013, Gut Pathogens.

[29]  Lucie Geurts,et al.  Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity , 2013, Proceedings of the National Academy of Sciences.

[30]  T. Preston,et al.  Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study. , 2013, The American journal of clinical nutrition.

[31]  I. Raskin,et al.  Blueberry polyphenol-enriched soybean flour reduces hyperglycemia, body weight gain and serum cholesterol in mice. , 2013, Pharmacological research.

[32]  P. Oteiza,et al.  Bioavailability of intact proanthocyanidins in the rat colon after ingestion of grape seed extract. , 2013, Journal of agricultural and food chemistry.

[33]  M. McCullough,et al.  Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations. , 2012, Nutrition reviews.

[34]  C. Xiang,et al.  Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer , 2012, PloS one.

[35]  H. Daniel,et al.  Acetatifactor muris gen. nov., sp. nov., a novel bacterium isolated from the intestine of an obese mouse , 2012, Archives of Microbiology.

[36]  Patrice D Cani,et al.  Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity , 2012, Gut microbes.

[37]  I. Raskin,et al.  Efficient sorption of polyphenols to soybean flour enables natural fortification of foods. , 2012, Food chemistry.

[38]  Ian D. Caterson,et al.  Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice , 2012, PloS one.

[39]  N. Han,et al.  Probiotic properties of Weissella strains isolated from human faeces. , 2012, Anaerobe.

[40]  V. Fogliano,et al.  Polyphenols and Human Health: A Prospectus , 2011, Critical reviews in food science and nutrition.

[41]  Gary Williamson,et al.  Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. , 2010, Molecular nutrition & food research.

[42]  R. Prior,et al.  Multi-laboratory validation of a standard method for quantifying proanthocyanidins in cranberry powders. , 2010, Journal of the science of food and agriculture.

[43]  E. Negri,et al.  Flavonoids, proanthocyanidins, and the risk of stomach cancer , 2010, Cancer Causes & Control.

[44]  A. Scalbert,et al.  Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse , 2010, British Journal of Nutrition.

[45]  Paul L. Huang.  A comprehensive definition for metabolic syndrome , 2009, Disease Models & Mechanisms.

[46]  Jungmin Lee,et al.  Determination of total monomeric anthocyanin pigment content of fruit juices, beverages, natural colorants, and wines by the pH differential method: collaborative study. , 2005, Journal of AOAC International.

[47]  Paul Sharp,et al.  Dietary polyphenols decrease glucose uptake by human intestinal Caco‐2 cells , 2005, FEBS letters.

[48]  W. D. de Vos,et al.  Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. , 2004, International journal of systematic and evolutionary microbiology.

[49]  Kenichi Yoshida,et al.  Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase Published, JLR Papers in Press, September 16, 2002. DOI 10.1194/jlr.C200010-JLR200 , 2002, Journal of Lipid Research.

[50]  O. Kwon,et al.  Flavonoid Inhibition of Sodium-dependent Vitamin C Transporter 1 (SVCT1) and Glucose Transporter Isoform 2 (GLUT2), Intestinal Transporters for Vitamin C and Glucose* , 2002, The Journal of Biological Chemistry.

[51]  R. Lamuela-Raventós,et al.  Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent , 1999 .

[52]  A. Stams,et al.  Growth of Syntrophic Propionate-Oxidizing Bacteria with Fumarate in the Absence of Methanogenic Bacteria , 1993, Applied and environmental microbiology.