The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks.

[1]  M. Fowler,et al.  Clinical Practice Recommendations , 2009, Clinical Diabetes.

[2]  Elisavet H. Fotiadou,et al.  Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity , 2009, The FEBS journal.

[3]  Avani A. Pendse,et al.  Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond This work was supported by National Institutes of Health Grant HL-042630. Published, JLR Papers in Press, December 5, 2008. , 2009, Journal of Lipid Research.

[4]  A. Mooradian.  Dyslipidemia in type 2 diabetes mellitus , 2009, Nature Clinical Practice Endocrinology &Metabolism.

[5]  T. Lehtimäki,et al.  Interactions of Functional Apolipoprotein E Gene Promoter Polymorphisms With Smoking on Aortic Atherosclerosis , 2008, Circulation. Cardiovascular genetics.

[6]  L. Groop,et al.  Variation in GYS1 Interacts with Exercise and Gender to Predict Cardiovascular Mortality , 2007, PloS one.

[7]  M. Kanzaki,et al.  Involvement of Apolipoprotein E in Excess Fat Accumulation and Insulin Resistance , 2007, Diabetes.

[8]  T. Lehtimäki,et al.  Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults Published, JLR Papers in Press, March 9, 2006. , 2006, Journal of Lipid Research.

[9]  A. D. de Craen,et al.  ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age , 2006, PLoS medicine.

[10]  D. Lairon,et al.  The apolipoprotein E gene promoter (-219G/T) polymorphism determines insulin sensitivity in response to dietary fat in healthy young adults. , 2005, The Journal of nutrition.

[11]  Terho Lehtimäki,et al.  The association of the apolipoprotein E gene promoter polymorphisms and haplotypes with serum lipid and lipoprotein concentrations. , 2005, Atherosclerosis.

[12]  R. Frants,et al.  Apolipoprotein E polymorphism in the Netherlands and its effect on plasma lipid and apolipoprotein levels , 1988, Human Genetics.

[13]  A. Pfeufer,et al.  Apolipoprotein E gene polymorphisms and thrombosis and restenosis after coronary artery stenting Published, JLR Papers in Press, October 1, 2004. DOI 10.1194/jlr.M400148-JLR200 , 2004, Journal of Lipid Research.

[14]  P. Pérez-Martínez,et al.  Apolipoprotein E gene promoter -219G->T polymorphism increases LDL-cholesterol concentrations and susceptibility to oxidation in response to a diet rich in saturated fat. , 2004, The American journal of clinical nutrition.

[15]  T. Lehtimäki,et al.  Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease , 2004, Human Genetics.

[16]  P. Wilson,et al.  Obesity modulates the association among APOE genotype, insulin, and glucose in men. , 2003, Obesity research.

[17]  J. Ordovás,et al.  The influence of the apolipoprotein E gene promoter (−219G/ T) polymorphism on postprandial lipoprotein metabolism in young normolipemic males Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300124-JLR200 , 2003, Journal of Lipid Research.

[18]  I. Simpson,et al.  Independent effects of the −219 G>T and ε2/ε3/ε4 polymorphisms in the apolipoprotein E gene on coronary artery disease: The Southampton Atherosclerosis Study , 2003, European Journal of Human Genetics.

[19]  Berrit C Stroehla,et al.  Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. , 2002, American journal of epidemiology.

[20]  M. Quon,et al.  Repeatability characteristics of simple indices of insulin resistance: implications for research applications. , 2001, The Journal of clinical endocrinology and metabolism.

[21]  I. Vauhkonen,et al.  Apolipoprotein E gene promoter (–219G/T) polymorphism is associated with premature coronary heart disease , 2001, Journal of Molecular Medicine.

[22]  A. Onat.  Risk factors and cardiovascular disease in Turkey. , 2001, Atherosclerosis.

[23]  R. Mahley,et al.  Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. , 2000, Journal of lipid research.

[24]  D. Singer,et al.  Apolipoprotein E isoform polymorphisms are not associated with insulin resistance: the Framingham Offspring Study. , 2000, Diabetes care.

[25]  D. Arveiler,et al.  Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations-the ECTIM study. , 2000, Human molecular genetics.

[26]  J. Breslow.  Genetics of lipoprotein abnormalities associated with coronary artery disease susceptibility. , 2000, Annual review of genetics.

[27]  T. Lehtimäki,et al.  Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: an autopsy study. , 1999, Circulation.

[28]  M. Bullido,et al.  Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene , 1998, FEBS letters.

[29]  B. Howard,et al.  Apolipoprotein E Polymorphism and Insulin Levels in a Biethnic Population , 1995, Diabetes Care.

[30]  C. Bouchard,et al.  Apolipoprotein E Polymorphism Modifies Relation of Hyperinsulinemia to Hypertriglyceridemia , 1993, Diabetes.

[31]  G. Reaven.  Role of Insulin Resistance in Human Disease , 1988, Diabetes.

[32]  G. Bruns,et al.  Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene. , 1985, The Journal of biological chemistry.

[33]  R. Mahley,et al.  Human apolipoprotein E. The complete amino acid sequence. , 1982, The Journal of biological chemistry.

[34]  J. Breslow,et al.  Human apolipoprotein E isoprotein subclasses are genetically determined. , 1981, American journal of human genetics.

[35]  G. Utermann,et al.  Polymorphism of apolipoprotein E , 1979, Clinical genetics.