Hierarchical elastomer tuned self-powered pressure sensor for wearable multifunctional cardiovascular electronics

Abstract Wearable pressure sensors, as essential components of flexible wearable electronics, may play important roles in early diagnosis and mortality prevention for cardiovascular healthcare. However, traditional self-powered pressure sensors can hardly obtain both high sensitivity and wide pressure range, which makes perceiving both cardiac and vascular signals in a wearable self-powered way challenging as these physiological signals not only have imperceptible changes but also span a broad pressure range. Here, we develop a flexible hierarchical elastomer tuned self-powered pressure sensor, which achieves both high-sensitivity and wide pressure range, showing a high sensitivity of 7.989 V kPa−1 and wide pressure range of 0.1–60 kPa simultaneously. Fast response (40 ms) and high signal noise ratio (38 db) with good stability are also achieved. We demonstrate that the self-powered pressure sensor can not only sensitively monitor pulse, artery and heart condition but also monitor the wide range blood pressure, which satisfies the diverse needs of wearable cardiovascular healthcare. As most of the pressure related to human interface is less than 50 kPa, we envision the sensor holds great potential in wearable electronics, mobile healthcare and human-machine interaction.

[1]  Zhiming Lin,et al.  Large‐Scale and Washable Smart Textiles Based on Triboelectric Nanogenerator Arrays for Self‐Powered Sleeping Monitoring , 2018 .

[2]  J. Blacher,et al.  Twenty-Four-Hour Ambulatory Pulse Wave Analysis in Hypertension Management: Current Evidence and Perspectives , 2016, Current Hypertension Reports.

[3]  Chuan Wang,et al.  Nanogenerator-based dual-functional and self-powered thin patch loudspeaker or microphone for flexible electronics , 2017, Nature Communications.

[4]  M. De Buyzere,et al.  Numerical Validation of a New Method to Assess Aortic Pulse Wave Velocity from a Single Recording of a Brachial Artery Waveform with an Occluding Cuff , 2010, Annals of Biomedical Engineering.

[5]  Fei Xu,et al.  Sensitive and Wearable Optical Microfiber Sensor for Human Health Monitoring , 2018, Advanced Materials Technologies.

[6]  U. Rajendra Acharya,et al.  Heart rate variability: a review , 2006, Medical and Biological Engineering and Computing.

[7]  Jamil Mayet,et al.  Use of simultaneous pressure and velocity measurements to estimate arterial wave speed at a single site in humans. , 2006, American journal of physiology. Heart and circulatory physiology.

[8]  Xue Wang,et al.  Rotation sensing and gesture control of a robot joint via triboelectric quantization sensor , 2018, Nano Energy.

[9]  Michael Böhm,et al.  2013 ESH/ESC Guidelines for the management of arterial hypertension , 2007, Blood pressure.

[10]  Kaushik Parida,et al.  Self-powered pressure sensor for ultra-wide range pressure detection , 2017, Nano Research.

[11]  W. Stevenson,et al.  Patterns of beat-to-beat heart rate variability in advanced heart failure. , 1992, American heart journal.

[12]  Zhong Lin Wang,et al.  Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays , 2006, Science.

[13]  G Parati,et al.  Blood pressure measuring devices: recommendations of the European Society of Hypertension , 2001, BMJ : British Medical Journal.

[14]  Zhong Lin Wang On Maxwell's displacement current for energy and sensors: the origin of nanogenerators , 2017 .

[15]  Bo Wang,et al.  Noncontact Heartbeat and Respiration Monitoring Based on a Hollow Microstructured Self-Powered Pressure Sensor. , 2018, ACS applied materials & interfaces.

[16]  Zhong Lin Wang,et al.  Flexible triboelectric generator , 2012 .

[17]  Carmen C. Y. Poon,et al.  An Armband Wearable Device for Overnight and Cuff-Less Blood Pressure Measurement , 2014, IEEE Transactions on Biomedical Engineering.

[18]  Zhong Lin Wang,et al.  Eye motion triggered self-powered mechnosensational communication system using triboelectric nanogenerator , 2017, Science Advances.

[19]  Sanat S Bhole,et al.  Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin , 2014, Science.

[20]  Yasmin,et al.  Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’ , 2010, European heart journal.

[21]  Marimuthu Palaniswami,et al.  Do existing measures of Poincare plot geometry reflect nonlinear features of heart rate variability? , 2001, IEEE Transactions on Biomedical Engineering.

[22]  Jun Zhou,et al.  Theoretical study and structural optimization of a flexible piezoelectret-based pressure sensor , 2018 .

[23]  Jun Zhou,et al.  Paper‐Based Active Tactile Sensor Array , 2015, Advanced materials.

[24]  B. Norrving,et al.  Global atlas on cardiovascular disease prevention and control. , 2011 .

[25]  Carmen C. Y. Poon,et al.  Cuff-less and Noninvasive Measurements of Arterial Blood Pressure by Pulse Transit Time , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[26]  Xin Jiang,et al.  A Wearable and Highly Sensitive Graphene Strain Sensor for Precise Home-Based Pulse Wave Monitoring. , 2017, ACS sensors.

[27]  Zhong Lin Wang On the first principle theory of nanogenerators from Maxwell's equations , 2020 .

[28]  Jie Chen,et al.  A highly sensitive, self-powered triboelectric auditory sensor for social robotics and hearing aids , 2018, Science Robotics.

[29]  Junwen Zhong,et al.  Flexible THV/COC Piezoelectret Nanogenerator for Wide-Range Pressure Sensing. , 2018, ACS applied materials & interfaces.

[30]  Zhaona Wang,et al.  Eardrum‐Inspired Active Sensors for Self‐Powered Cardiovascular System Characterization and Throat‐Attached Anti‐Interference Voice Recognition , 2015, Advanced materials.

[31]  Sang-Suk Lee,et al.  Measurement of Blood Pressure Using an Arterial Pulsimeter Equipped with a Hall Device , 2011, Sensors.

[32]  Zhong Lin Wang,et al.  Theoretical study of contact-mode triboelectric nanogenerators as an effective power source , 2013 .

[33]  Zhong Lin Wang,et al.  Finger typing driven triboelectric nanogenerator and its use for instantaneously lighting up LEDs , 2013 .

[34]  Zhong Lin Wang Triboelectric nanogenerators as new energy technology for self-powered systems and as active mechanical and chemical sensors. , 2013, ACS nano.

[35]  Huimin Yu,et al.  Surface charge self-recovering electret film for wearable energy conversion in a harsh environment , 2016 .

[36]  Qiang He,et al.  Triboelectric vibration sensor for a human-machine interface built on ubiquitous surfaces , 2019, Nano Energy.

[37]  Zhong Lin Wang,et al.  Skin-inspired highly stretchable and conformable matrix networks for multifunctional sensing , 2018, Nature Communications.

[38]  Chang Kyu Jeong,et al.  Self‐Powered Real‐Time Arterial Pulse Monitoring Using Ultrathin Epidermal Piezoelectric Sensors , 2017, Advanced materials.

[39]  Zhiyi Wu,et al.  A Stretchable Yarn Embedded Triboelectric Nanogenerator as Electronic Skin for Biomechanical Energy Harvesting and Multifunctional Pressure Sensing , 2018, Advanced materials.

[40]  P. Chowienczyk,et al.  Determination of age-related increases in large artery stiffness by digital pulse contour analysis. , 2002, Clinical science.

[41]  Yi Yang,et al.  Graphene-Paper Pressure Sensor for Detecting Human Motions. , 2017, ACS nano.

[42]  Zhong Lin Wang,et al.  Transparent and Self-Powered Multistage Sensation Matrix for Mechanosensation Application. , 2017, ACS nano.

[43]  Hilmi R. Dajani,et al.  Oscillometric Blood Pressure Estimation: Past, Present, and Future , 2015, IEEE Reviews in Biomedical Engineering.

[44]  Yonggang Huang,et al.  High performance piezoelectric devices based on aligned arrays of nanofibers of poly(vinylidenefluoride-co-trifluoroethylene) , 2013, Nature Communications.

[45]  Yaping Zang,et al.  Advances of flexible pressure sensors toward artificial intelligence and health care applications , 2015 .

[46]  Jan Havlik,et al.  Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study , 2019, Sensors.

[47]  U. Eisenberger,et al.  Pulse contour analysis: a valid assessment of central arterial stiffness in children? , 2008, Pediatric Nephrology.

[48]  Phyllis K Stein,et al.  Traditional and Nonlinear Heart Rate Variability Are Each Independently Associated with Mortality after Myocardial Infarction , 2005, Journal of cardiovascular electrophysiology.

[49]  John Allen Photoplethysmography and its application in clinical physiological measurement , 2007, Physiological measurement.

[50]  Zhong Lin Wang,et al.  Flexible Weaving Constructed Self‐Powered Pressure Sensor Enabling Continuous Diagnosis of Cardiovascular Disease and Measurement of Cuffless Blood Pressure , 2018, Advanced Functional Materials.

[51]  Gamage Upeksha Ganegoda,et al.  Secondary Prevention of Cardiovascular Diseases and Application of Technology for Early Diagnosis , 2018, BioMed research international.