Epidermal growth factor: mechanisms of action.

[1]  G. Todaro,et al.  Human transforming growth factor. Production by a melanoma cell line, purification, and initial characterization. , 1982, The Journal of biological chemistry.

[2]  M. Pittenger,et al.  Cell surface insertion of exogenous epidermal growth factor receptors into receptor- mutant cells: demonstration of insertion in the absence of added fusogenic agents. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Michael Chinkers,et al.  A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. , 1982, The Journal of biological chemistry.

[4]  M. Sporn,et al.  Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF , 1982, Nature.

[5]  Y. Yarden,et al.  Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[6]  I. Pastan,et al.  Journey to the center of the cell: role of the receptosome. , 1981, Science.

[7]  E. Rozengurt,et al.  Stimulation of DNA synthesis by transient exposure of cell cultures to TPA or polypeptide mitogens: Induction of competence or incomplete removal? , 1981, Journal of cellular physiology.

[8]  N. Colburn,et al.  Specific binding of transforming growth factor correlates with promotion of anchorage independence in EGF receptorless mouse JB6 cells. , 1981, Biochemical and biophysical research communications.

[9]  M. Das.  Initiation of nuclear DNA replication: evidence for formation of committed prereplicative cellular state. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[10]  Y. Yarden,et al.  A non-mitogenic analogue of epidermal growth factor enhances the phosphorylation of endogenous membrane proteins. , 1981, Biochemical and biophysical research communications.

[11]  Y. Shimizu,et al.  Insulin and epidermal growth factor stimulate poly ADP-ribosylation. , 1981, Biochemical and biophysical research communications.

[12]  E. Rozengurt,et al.  Melittin stimulates Na entry, Na-K pump activity and DNA synthesis in quiescent cultures of mouse cells , 1981, Cell.

[13]  E. Rozengurt,et al.  Vasopressin inhibition of epidermal growth factor binding to cultured mouse cells. , 1981, The Journal of biological chemistry.

[14]  L. W. Mozes.  Cellular Responses to Molecular Modulators , 1981 .

[15]  H. Varmus,et al.  The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine. , 1980, The Journal of biological chemistry.

[16]  T. L. Blundell,et al.  Hormone families: pancreatic hormones and homologous growth factors , 1980, Nature.

[17]  R. Erikson,et al.  Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus-transforming gene product , 1980, Cell.

[18]  G. Todaro,et al.  Vitamin K3 (menadione) and related quinones, like tumor-promoting phorbol esters, alter the affinity of epidermal growth factor for its membrane receptors. , 1980, The Journal of biological chemistry.

[19]  S. Cohen,et al.  Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. , 1980, The Journal of biological chemistry.

[20]  G. Todaro,et al.  Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Das,et al.  Effect of methylamine on internalization, processing and biological activation of epidermal growth factor receptor , 1980, FEBS letters.

[22]  R. Kucherlapati,et al.  Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[23]  A. Moody,et al.  Demonstration of specific receptors for EGF—urogastrone in isolated rat intestinal epithelial cells , 1980, FEBS letters.

[24]  M. Sporn,et al.  Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Y. Shimizu,et al.  Genetics of cell surface receptors for bioactive polypeptides: binding of epidermal growth factor is associated with the presence of human chromosome 7 in human-mouse cell hybrids. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[26]  G. Carpenter,et al.  Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. , 1980, The Journal of biological chemistry.

[27]  G. Carpenter,et al.  Production and characterization of antibody blocking epidermal growth factor:receptor interactions. , 1980, Biochimica et biophysica acta.

[28]  M. Nilsen-Hamilton,et al.  Selective stimulation by mitogens of incorporation of 35S-methionine into a family of proteins released into the medium by 3T3 cells , 1980, Cell.

[29]  M. Hollenberg,et al.  Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[30]  G. Todaro,et al.  Sarcoma growth factor from mouse sarcoma virus-transformed cells. Purification by binding and elution from epidermal growth factor receptor-rich cells. , 1980, The Journal of biological chemistry.

[31]  M. Makman,et al.  Effect of tunicamycin on the turnover of epidermal growth factor receptors in cultured calf aorta smooth muscle cells. Comparison with IMR-90 human lung fibroblasts. , 1980, Biochimica et biophysica acta.

[32]  G. Carpenter,et al.  Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes. , 1980, Biochemistry.

[33]  D. Gospodarowicz,et al.  Role of the degradation process in the mitogenic effect of epidermal growth factor. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[34]  T. Hunter,et al.  Transforming gene product of Rous sarcoma virus phosphorylates tyrosine , 1980, Proceedings of the National Academy of Sciences.

[35]  M. Das.  Mitogenic hormone-induced intracellular message: assay and partial characterization of an activator of DNA replication induced by epidermal growth factor. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[36]  E. Rozengurt,et al.  Colchicine inhibits epidermal growth factor degradation in 3T3 cells. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[37]  P. Linsley,et al.  Controlled proteolysis of EGF receptors: evidence for transmembrane distribution of the EGF binding and phosphate acceptor sites. , 1980, Journal of supramolecular structure.

[38]  M. Hollenberg,et al.  Isolation of the human placenta receptor for epidermal growth factor-urogastrone. , 1980, Nature.

[39]  I. Weinstein,et al.  Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[40]  M. Wrann,et al.  Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line. , 1979, The Journal of biological chemistry.

[41]  M. Brown,et al.  Receptor-mediated endocytosis: insights from the lipoprotein receptor system. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[42]  R. Ladda,et al.  Decrease in epidermal growth factor receptor levels and production of material enhancing epidermal growth factor binding accompany the temperature-dependent changes from normal to transformed phenotype. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[43]  G. Carpenter,et al.  Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor. , 1979, The Journal of biological chemistry.

[44]  S. Cohen,et al.  Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431 , 1979, The Journal of cell biology.

[45]  Pedro Cuatrecasas,et al.  Local aggregation of hormone–receptor complexes is required for activation by epidermal growth factor , 1979, Nature.

[46]  L. Burzio,et al.  ADP ribosylation of rat liver nucleosomal core histones. , 1979, The Journal of biological chemistry.

[47]  P. Linsley,et al.  Direct linkage of epidermal growth factor to its receptor , 1979, Nature.

[48]  R. Simmer,et al.  Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation , 1979, Nature.

[49]  C. Stiles,et al.  Dual control of cell growth by somatomedins and platelet-derived growth factor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[50]  E. Rozengurt,et al.  Inhibition of epidermal growth factor binding to surface receptors by tumor promotors. , 1979, Biochemical and biophysical research communications.

[51]  M. Hollenberg,et al.  Isolation of the human placenta receptor for epidermal growth factor-urogastrone , 1979, Nature.

[52]  R. Ladda,et al.  Radioreceptor assay for epidermal growth factor. , 1979, Analytical biochemistry.

[53]  C. F. Fox,et al.  Chemical cross-linking in biology. , 1979, Annual review of biophysics and bioengineering.

[54]  M. Hollenberg.  Epidermal growth factor-urogastrone, a polypeptide acquiring hormonal status. , 1979, Vitamins and hormones.

[55]  C. F. Fox,et al.  Internalization and processing of the EGF receptor in the induction of DNA synthesis in cultured fibroblasts: the endocytic activation hypothesis. , 1979, Journal of supramolecular structure.

[56]  G. Carpenter,et al.  Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro , 1978, Nature.

[57]  I. Weinstein,et al.  Tumor-promoting phorbol esters inhibit binding of epidermal growth factor to cellular receptors. , 1978, Science.

[58]  L. Orci,et al.  Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[59]  S. Singer,et al.  Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[60]  H. Herschman,et al.  Epidermal growth factor. Relationship between receptor regulation and mitogenesis in 3T3 cells. , 1978, The Journal of biological chemistry.

[61]  R. Ross,et al.  Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[62]  C. F. Fox,et al.  Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[63]  I. Pastan,et al.  Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[64]  D. Gospodarowicz,et al.  Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin , 1978, The Journal of cell biology.

[65]  D. Gospodarowicz,et al.  A comparison of the binding of epidermal growth factor to cultured granulosa and luteal cells. , 1978, The Journal of biological chemistry.

[66]  M. Hollenberg,et al.  Insulin and epidermal growth factor-urogastrone: affinity crosslinking to specific binding sites in rat liver membranes. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[67]  I. Pastan,et al.  Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis , 1978, Nature.

[68]  E. Rozengurt,et al.  Glycolysis of quiescent cultures of 3T3 cells. Addition of serum, epidermal growth factor, and insulin increases the activity of phosphofructokinase in a protein synthesis-independent manner. , 1978, The Journal of biological chemistry.

[69]  H. Gregory,et al.  The primary structure of human urogastrone. , 2009, International journal of peptide and protein research.

[70]  A. Mescher,et al.  The role of fibroblast growth factor and epidermal growth factorin the proliferative response of the corneal and lens epithelium. , 1977, Experimental eye research.

[71]  G. Carpenter,et al.  Influence of lectins on the binding of 125I-labeled EGF to human fibroblasts. , 1977, Biochemical and biophysical research communications.

[72]  C. Lloyd,et al.  Rapid isolation of plasma membranes in high yield from cultured fibroblasts. , 1977, The Biochemical journal.

[73]  K. Brown,et al.  Density-dependent regulation of growth of BSC-1 cells in cell culture: control of growth by serum factors. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[74]  C. Kahn,et al.  Effects of autoantibodies to the insulin receptor on isolated adipocytes. Studies of insulin binding and insulin action. , 1977, The Journal of clinical investigation.

[75]  H. Herschman,et al.  Variants of 3T3 cells lacking mitogenic response to epidermal growth factor. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[76]  M. Korner,et al.  Coupling of hormone receptors to adenylate cyclase of different cells by cell fusion , 1977, Nature.

[77]  H. Herschman,et al.  Specific radiolabeling of a cell surface receptor for epidermal growth factor. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[78]  B. Westermark.  Local starvation for epidermal growth factor cannot explain density-dependent inhibition of normal human glial cells. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[79]  J. Hassell,et al.  Elevated levels of cAMP alters the effect of epidermal growth factor in vitro on programmed cell death in the secondary palatal epithelium. , 1977, Experimental cell research.

[80]  G. Todaro,et al.  Nerve growth factor receptors on human melanoma cells in culture. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[81]  O. Hayaishi,et al.  Poly(ADP-ribose) and ADP-ribosylation of proteins. , 1977, Annual review of biochemistry.

[82]  E. Racker.  Why do tumor cells have a high aerobic glycolysis? , 1976, Journal of cellular physiology.

[83]  S. Colowick,et al.  Stimulation of sugar uptake in cultured fibroblasts by epidermal growth factor (EGF) and EGF‐binding arginine esterase , 1976, Journal of cellular physiology.

[84]  G. Carpenter,et al.  125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts , 1976, The Journal of cell biology.

[85]  G. Edelman,et al.  Initiation of replication in chromosomal DNA induced by extracts from proliferating cells. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[86]  S. Cohen,et al.  Conformation and unfolding thermodynamics of epidermal growth factor and derivatives. , 1976, Biochemistry.

[87]  G. Carpenter,et al.  Human epidermal growth factor and the proliferation of human fibroblasts , 1976, Journal of cellular physiology.

[88]  M. Hollenberg.  Receptors for insulin and epidermal growth factor: relation to synthesis of DNA in cultured rabbit lens epithelium. , 1975, Archives of biochemistry and biophysics.

[89]  H. Herschman,et al.  Initiation of 3T3 fibroblast cell division by epidermal growth factor , 1975, Journal of Cellular Physiology.

[90]  L. Heppel,et al.  Serum rapidly stimulates ouabain-sensitive 86-RB+ influx in quiescent 3T3 cells. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[91]  H. Gregory.  Isolation and structure of urogastrone and its relationship to epidermal growth factor , 1975, Nature.

[92]  J. Hassell.  The development of rat palatal shelves in vitro. An ultrastructural analysis of the inhibition of epithelial cell death and palate fusion by the epidermal growth factor. , 1975, Developmental biology.

[93]  G. Carpenter,et al.  Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts. , 1975, The Journal of biological chemistry.

[94]  R. Benbow,et al.  Cytoplasmic control of nuclear DNA synthesis during early development of Xenopus laevis: a cell-free assay. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[95]  P. Cuatrecasas,et al.  Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake. , 1975, The Journal of biological chemistry.

[96]  G. Carpenter,et al.  Human epidermal growth factor: isolation and chemical and biological properties. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[97]  H. Gregory,et al.  The isolation of the urogastrones - inhibitors of gastric acid secretion - from human urine. , 1975, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[98]  I. Mowszowicz,et al.  Submaxillary gland epidermal growth factor: a sensitive index of biologic androgen activity. , 1974, Endocrinology.

[99]  P. Cuatrecasas,et al.  Epidermal growth factor. Characteristics of specific binding in membranes from liver, placenta, and other target tissues. , 1974, Archives of biochemistry and biophysics.

[100]  S. Cohen,et al.  Epidermal growth factor: effects of androgens and adrenergic agents. , 1974, Endocrinology.

[101]  P. Cuatrecasas,et al.  Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[102]  H. Armelin.  Pituitary extracts and steroid hormones in the control of 3T3 cell growth. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[103]  T. Sugimura,et al.  Poly(adenosine diphosphate ribose). , 1973, Progress in nucleic acid research and molecular biology.

[104]  S. Cohen,et al.  The primary structure of epidermal growth factor. , 1972, The Journal of biological chemistry.

[105]  L. Frati,et al.  Selective binding of the epidermal growth factor and its specific effects on the epithelial cells of the cornea. , 1972, Experimental eye research.

[106]  S. Cohen,et al.  Radioimmunoassay of epidermal growth factor. , 1972, Endocrinology.

[107]  H. Temin,et al.  Stimulation by serum of multiplication of stationary chicken cells , 1971, Journal of cellular physiology.

[108]  W. Dewey,et al.  Inhibition of DNA synthesis in synchronized Chinese hamster cells treated in G1 with cycloheximide. , 1971, Experimental cell research.

[109]  S. Cohen,et al.  Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. , 1962, The Journal of biological chemistry.