Preliminary clinical experience with meptazinol, a new analgesic.
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The analgesic effect of intravenous meptazinol at various dosage levels was studied in 30 patients suffering from acute renal colic. Out of a total of 41 injections (dose range: 20 to 120 mg.) a favourable analgesic response was recorded on 39 occasions. The onset of action was rapid with the minimun duration of action of 1 hour. Higher doses increased the drug's action but were accompanied by nausea and dizziness. There was no overall effect on blood pressure or heart rate.
[1] B. Terhorst,et al. [The treatment of urocalculosis by medication. I. Spasmolysis and analgesia]. , 1971, Urologia internationalis.
[2] J. Lapides. The Physiology of the Intact Human Ureter 1,2 , 1948 .