Methods in macromolecular crystallography

The main theme of this text is the interactions of macromolecules and the consequences for biological function. The book brings together contributions from leading structural scientists who address challenging problems, such as crystallization of membrane proteins, the structures of large assemblies of proteins, proteins and RNA, proteins and DNA, and the structures of large viruses. Advances in macromolecular crystallography have provided new views of biology, and by working at the EM/Xray interface and by exploiting the potential of third generation synchrotron radiation sources for data collection from small crystals new targets can be addressed.