93 10 Years Screening for Retinopathy of Prematurity (ROP): Differences in Small (SGA) and Appropriately (AGA) Grown Infants.

BACKGROUND INFANTS BORN SGA HAVE BEEN REPORTED TO BE AT INCREASED RISK OF DEVELOPING SIGHT-THREATENING ROP(1).OBJECTIVE TO COMPARE THE PREVALENCE OF ROP IN SGA (BIRTH WEIGHT<10TH PERCENTILE) AND AGA INFANTS SCREENED AT THE SOUTH EAST SCOTLAND REGIONAL NEONATAL UNIT IN EDINBURGH FROM JANUARY 1993-JANUARY 2003.METHODS ALL INFANTS IN THIS TERTIARY REFERRAL NEONATAL UNIT WITH A GESTATIONAL AGE AT BIRTH OF <32 WEEKS OR BIRTH WEIGHT OF <1500G WERE SCREENED; FIRST AT POSTNATAL AGE OF 5–6 WEEKS AND THEN AT LEAST EVERY SECOND WEEK UNTIL FULL RETINAL VASCULARISATION. SCREENING WAS CARRIED OUT BY 2 DEDICATED PAEDIATRIC OPHTHALMOLOGISTS (EW AND BF) USING INDIRECT OPHTHALMOSCOPY AND RETINOPATHY WAS GRADED BY INTERNATIONAL CRITERIA (2). LASER PHOTOCOAGULATION WAS ADMINISTERED FOR INFANTS WITH THRESHOLD ROP (3). THE GRADE OF ROP, PRESENCE OF ROP AND ROP REQUIRING LASER TREATMENT WERE COMPARED FOR SGA AND AGA INFANTS USING CHI SQUARED TEST.RESULTS 830 INFANTS (208 [25% SGA]) WERE SCREENED. 38 (18%) SGA AND 127/622 (20%) AGA INFANTS HAD ROP. NO BABY OF GESTATION >28WEEKS REQUIRED TREATMENT FOR ROP.CONCLUSIONS SGA INFANTS BORN <28WEEKS GESTATION HAD AN INCREASED RISK OF DEVELOPING ROP AND ALTHOUGH THERE WAS A TREND TO WORSE ROP, NO MORE REQUIRED TREATMENT.