Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming.

[1]  Ethan M. Goldberg,et al.  Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells , 2015, Development.

[2]  Makiko Iwafuchi‐Doi,et al.  Pioneer transcription factors in cell reprogramming , 2014, Genes & development.

[3]  Matheus B. Victor,et al.  Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts , 2014, Neuron.

[4]  Arturo Alvarez-Buylla,et al.  Inhibitory Interneuron Progenitor Transplantation Restores Normal Learning and Memory in ApoE4 Knock-In Mice without or with Aβ Accumulation , 2014, The Journal of Neuroscience.

[5]  Alexander E. Dityatev,et al.  Remote control of induced dopaminergic neurons in parkinsonian rats. , 2014, The Journal of clinical investigation.

[6]  M. Ross,et al.  Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition , 2014, Proceedings of the National Academy of Sciences.

[7]  F. Benfenati,et al.  REST/NRSF‐mediated intrinsic homeostasis protects neuronal networks from hyperexcitability , 2013, The EMBO journal.

[8]  Joshua C. Chang,et al.  Small Molecules Enable Neurogenin 2 to Efficiently Convert Human Fibroblasts to Cholinergic Neurons , 2013, Nature Communications.

[9]  T. Südhof,et al.  Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells , 2013, Neuron.

[10]  Vania Broccoli,et al.  Rapid Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Through a Single‐Step Procedure Using Cell Lineage Transcription Factors , 2013, Stem cells translational medicine.

[11]  J. Rubenstein,et al.  Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. , 2013, Cell stem cell.

[12]  S. Anderson,et al.  Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. , 2013, Cell stem cell.

[13]  J. Rubenstein,et al.  GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior , 2013, Nature Neuroscience.

[14]  Leonardo Beccari,et al.  Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh , 2013, Development.

[15]  J. Rubenstein,et al.  Forebrain GABAergic Neuron Precursors Integrate into Adult Spinal Cord and Reduce Injury-Induced Neuropathic Pain , 2012, Neuron.

[16]  B. Nadel,et al.  TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression. , 2012, Cancer cell.

[17]  Kevin Eggan,et al.  Conversion of mouse and human fibroblasts into functional spinal motor neurons. , 2011, Cell stem cell.

[18]  Michael Q. Zhang,et al.  Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx-Repressed Enhancer at Cdx2 and a Potential Indicator of Esophageal Adenocarcinoma Development , 2011, PLoS genetics.

[19]  Maria Teresa Dell'Anno,et al.  Direct generation of functional dopaminergic neurons from mouse and human fibroblasts , 2011, Nature.

[20]  Y. Yanagawa,et al.  Subregional Specification of Embryonic Stem Cell-Derived Ventral Telencephalic Tissues by Timed and Combinatory Treatment with Extrinsic Signals , 2011, The Journal of Neuroscience.

[21]  M. Calcagnotto,et al.  Effect of neuronal precursor cells derived from medial ganglionic eminence in an acute epileptic seizure model , 2010, Epilepsia.

[22]  K. Deisseroth,et al.  Dlx5 and Dlx6 Regulate the Development of Parvalbumin-Expressing Cortical Interneurons , 2010, The Journal of Neuroscience.

[23]  S. Anderson,et al.  Prospective Isolation of Cortical Interneuron Precursors from Mouse Embryonic Stem Cells , 2010, The Journal of Neuroscience.

[24]  A. Kriegstein,et al.  Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats. , 2010, Cell stem cell.

[25]  Michael P Stryker,et al.  Cortical Plasticity Induced by Inhibitory Neuron Transplantation , 2010, Science.

[26]  D. Price,et al.  The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice , 2010, Development.

[27]  Thomas Vierbuchen,et al.  Direct conversion of fibroblasts to functional neurons by defined factors , 2010, Nature.

[28]  V. Broccoli,et al.  Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. , 2009, Developmental biology.

[29]  J. Rubenstein,et al.  Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice , 2009, Proceedings of the National Academy of Sciences.

[30]  M. Ekker,et al.  The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer , 2007, Development.

[31]  Y. Yanagawa,et al.  Lhx6 Activity Is Required for the Normal Migration and Specification of Cortical Interneuron Subtypes , 2007, The Journal of Neuroscience.

[32]  L. Nguyen,et al.  Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. , 2006, Developmental cell.

[33]  M. Calcagnotto,et al.  Cortical Inhibition Modified by Embryonic Neural Precursors Grafted into the Postnatal Brain , 2006, The Journal of Neuroscience.

[34]  T. Kaneko,et al.  Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67‐GFP knock‐in mouse , 2003, The Journal of comparative neurology.

[35]  W. Dobyns,et al.  Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans , 2002, Nature Genetics.

[36]  J. Rubenstein,et al.  Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. , 2002, Development.

[37]  O. Marín,et al.  A long, remarkable journey: Tangential migration in the telencephalon , 2001, Nature Reviews Neuroscience.

[38]  S. Anderson,et al.  Distinct cortical migrations from the medial and lateral ganglionic eminences. , 2001, Development.

[39]  F. Guillemot,et al.  A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. , 2000, Genes & development.

[40]  A. Erisir,et al.  Function of specific K(+) channels in sustained high-frequency firing of fast-spiking neocortical interneurons. , 1999, Journal of neurophysiology.

[41]  C. Walsh,et al.  Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons , 1999, Neuron.

[42]  F. Guillemot,et al.  Mash1 regulates neurogenesis in the ventral telencephalon. , 1999, Development.

[43]  B. Rudy,et al.  Developmental expression and functional characterization of the potassium-channel subunit Kv3.1b in parvalbumin-containing interneurons of the rat hippocampus , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[44]  R. Roeder,et al.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.

[45]  M. Ekker,et al.  Ectopic expression of the Dlx genes induces glutamic acid decarboxylase and Dlx expression. , 2002, Development.