7 – Hydroperoxide Metabolism and Oxidant Generation in Platelets

[1]  D. Nugteren,et al.  Non-enzymic conversion of all-cis 8 11 14-eicosatriencoic acid into prostaglandin E1. , 2010 .

[2]  L. Marnett,et al.  Mechanism of the stimulation of prostaglandin H synthase and prostacyclin synthase by the antithrombotic and antimetastatic agent, nafazatrom. , 1984, Molecular pharmacology.

[3]  R. Bryant,et al.  Hydroperoxy fatty acid formation in selenium deficient rat platelets: coupling of glutathione peroxidase to the lipoxygenase pathway. , 1983, Biochemical and biophysical research communications.

[4]  L. Marnett,et al.  Reaction of the antithrombotic and antimetastatic agent, nafazatrom, with oxidizing radicals. , 1983, Biochemical and Biophysical Research Communications - BBRC.

[5]  M. Verstraete,et al.  Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. , 1983, Biochemical pharmacology.

[6]  L. Marnett,et al.  Hematin-catalyzed rearrangement of hydroperoxylinoleic acid to epoxy alcohols via an oxygen rebound , 1983 .

[7]  B. Samuelsson,et al.  Arachidonic acid epoxides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acids. , 1983, The Journal of biological chemistry.

[8]  B. Samuelsson Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. , 1983, Science.

[9]  D. Dewitt,et al.  Purification of prostacyclin synthase from bovine aorta by immunoaffinity chromatography. Evidence that the enzyme is a hemoprotein. , 1983, The Journal of biological chemistry.

[10]  R. Bryant,et al.  Role of glutathione peroxidase and hexose monophosphate shunt in the platelet lipoxygenase pathway. , 1982, The Journal of biological chemistry.

[11]  P. Strittmatter,et al.  Reduced pyridine nucleotides and cytochrome b5 as electron donors for prostaglandin synthetase reconstituted in dimyristyl phosphatidylcholine vesicles. , 1982, The Journal of biological chemistry.

[12]  J. Maclouf,et al.  Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[13]  B. Tainer,et al.  The free radical formed during the hydroperoxide-mediated deactivation of ram seminal vesicles is hemoprotein-derived. , 1982, The Journal of biological chemistry.

[14]  K. Honn,et al.  Nafazatrom (bay g 6575) inhibition of tumor cell lipoxygenase activity and cellular proliferation , 1982, FEBS letters.

[15]  L. Marnett,et al.  Free radical epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by hematin and polyunsaturated fatty acid hydroperoxides , 1981 .

[16]  L. Marnett,et al.  Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis. , 1981, Life sciences.

[17]  R. Kleiman,et al.  Degradation of linoleic acid hydroperoxides by a cysteine . FeCl3 catalyst as a model for similar biochemical reactions. II. Specificity in formation of fatty acid epoxides. , 1981, Biochimica et biophysica acta.

[18]  L. Castle,et al.  Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase. , 1981, Biochemical pharmacology.

[19]  P. Needleman,et al.  Inactivation of vascular prostacyclin synthetase by platelet lipoxygenase products. , 1980, Biochemical and biophysical research communications.

[20]  M. Hamberg,et al.  On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase. , 1980, Biochemical and biophysical research communications.

[21]  B. Tainer,et al.  A carbon-centered free radical intermediate in the prostaglandin synthetase oxidation of arachidonic acid. Spin trapping and oxygen uptake studies. , 1980, The Journal of biological chemistry.

[22]  J. Bianchine,et al.  The production of the arachidonate metabolite HETE in vascular tissue , 1979, Nature.

[23]  R. L. Jones,et al.  The identification of an epoxy-hydroxy acid as a product from the incubation of arachidonic acid with washed blood platelets. , 1979, Prostaglandins.

[24]  L. Marnett,et al.  Peroxidatic oxidation of benzo[a]pyrene and prostaglandin biosynthesis. , 1979, Biochemistry.

[25]  R. Egan,et al.  Peroxidase-dependent deactivation of prostacyclin synthetase. , 1979, The Journal of biological chemistry.

[26]  S. Yamamoto,et al.  Prostaglandin hydroperoxidase, an integral part of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. , 1979, The Journal of biological chemistry.

[27]  M. Buytenhek,et al.  On the haemoprotein character of prostaglandin endoperoxide synthetase. , 1979, Biochimica et biophysica acta.

[28]  R. L. Jones,et al.  The identification of trihydroxyeicosatrienoic acids as products from the incubation of arachidonic acid with washed blood platelets. , 1978, Prostaglandins.

[29]  A. Marcus The role of lipids in platelet function: with particular reference to the arachidonic acid pathway. , 1978, Journal of lipid research.

[30]  J. Salmon,et al.  Enhancement of anaphylactic mediator release from guinea-pig perfused lungs by fatty acid hydroperoxides. , 1978, Prostaglandins.

[31]  R. Egan,et al.  Mechanism for irreversible self-deactivation of prostaglandin synthetase. , 1976, The Journal of biological chemistry.

[32]  J. Vane,et al.  A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation. , 1976, Prostaglandins.

[33]  W. Lands,et al.  Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme. , 1976, The Journal of biological chemistry.

[34]  M. Hamberg,et al.  Metabolism of 8,11,14-eicosatrienoic acid in human platelets. , 1976, Biochimica et biophysica acta.

[35]  S. Yamamoto,et al.  Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. , 1976, The Journal of biological chemistry.

[36]  M. Funk,et al.  Letter: Peroxy radical cyclization as a model for prostaglandin biosynthesis. , 1975, The Journal of organic chemistry.

[37]  Grosskopf,et al.  Oxidation of cytochrome b5 by hydroperoxides in rat liver. , 1975, European journal of biochemistry.

[38]  M. Hamberg,et al.  Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[39]  H. Gardner Decomposition of linoleic acid hydroperoxides. Enzymic reactions compared with nonenzymic. , 1975, Journal of agricultural and food chemistry.

[40]  D. Nugteren Arachidonate lipoxygenase in blood platelets. , 1975, Biochimica et biophysica acta.

[41]  M. Hamberg,et al.  Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[42]  M. Hamberg,et al.  Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[43]  M. Hamberg,et al.  Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[44]  D. Nugteren,et al.  Isolation and properties of intermediates in prostaglandin biosynthesis. , 1973, Biochimica et biophysica acta.

[45]  J. Vliegenthart,et al.  The detection of linoleic acid radicals in the anaerobic reaction of lipoxygenase. , 1973, Biochimica et biophysica acta.

[46]  M. Hamberg,et al.  Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[47]  W. Lands,et al.  Pathophysiologic modulation of arachidonate metabolism. , 1984, Clinical physiology and biochemistry.

[48]  E. Cadenas,et al.  Singlet oxygen formation detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2. , 1983, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[49]  R. Bryant,et al.  Role of selenium-dependent glutathione peroxidase in platelet lipoxygenase metabolism. , 1981, Progress in lipid research.

[50]  E. Goetzl,et al.  Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid. , 1980, Prostaglandins.

[51]  R. Bryant,et al.  Isolation of a new lipoxygenase metabolite of arachidonic acid, 8. 11, 12-trihydroxy-5,9,14-eicosatrienoic acid from human platelets. , 1979, Prostaglandins.