While Lowering Quality Of Life More Americans Living Longer With Cardiovascular Disease Will Increase Costs

In the past several decades, some risk factors for cardiovascular disease have improved, while others have worsened. For example, smoking rates have dropped and treatment rates for cardiovascular disease have increased—factors that have made the disease less fatal. At the same time, Americans’ average body mass index and incidence of diabetes have increased as the population continues to live longer— factors that have made cardiovascular disease more prevalent. To assess the aggregate impact of these opposing trends, we used the nine National Health and Nutrition Examination Survey waves from 1973 to 2010 to forecast total cardiovascular disease risk and prevalence from 2015 to 2030. We found that continued improvements in cardiovascular disease treatment and declining smoking rates will not outweigh the influence of increasing population age and obesity on cardiovascular disease risk. Given an aging population, an obesity epidemic, and declining mortality from the disease, the United States should expect to see a sharp rise in the health care costs, disability, and reductions in quality of life associated with increased prevalence of cardiovascular disease. Policies that target the treatment of high blood pressure and cholesterol and the reduction of obesity will be necessary to curb the imminent spike in cardiovascular disease prevalence. U S trends in cardiovasculardisease over the past several decades tell two stories. One is encouraging: Age-adjusted rates for cardiovascular disease mortality declined from 517 per 100,000 in 1981 to 244 per 100,000 in 2008. The second story, however, is sobering: Cardiovascular disease remains the leading cause of death and of health care costs in theUnited States.Over the past twenty years the incidence and prevalence of cardiovascular disease appear to be steady or rising, based on events observed in large cohort studies and estimates from nationally representative surveys. These opposing trends inmortality and nonfatal burden of cardiovascular disease can be at least partially explained by the improvements in treatment that have made cardiovascular disease less fatal but more prevalent. To reduce the incidence and prevalence of cardiovascular disease, prevention efforts shouldbe intensified. Intervening before initial or subsequent cardiovascular disease events occur could avoid substantial mortality, morbidity, and health care costs attributable to cardiovascular disease. With these prevention-related goals in mind, the use of lipid-lowering and antihypertensive medication has increased over the past forty years, and blood pressure and cholesterol levels have declined as a result. Smoking has also steadily decreased over the past forty years, doi: 10.1377/hlthaff.2013.0449

[1]  M. Slattery,et al.  Changing population characteristics, effect-measure modification, and cancer risk factor identification , 2007, Epidemiologic perspectives & innovations : EP+I.

[2]  M. Pencina,et al.  General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study , 2008, Circulation.

[3]  G. Silvestri,et al.  Predicted impact of attaining smoking reduction goals on mortality. , 2001, Southern medical journal.

[4]  David S. Jones,et al.  The contributions of prevention and treatment to the decline in cardiovascular mortality: lessons from a forty-year debate. , 2012, Health affairs.

[5]  R. Cote,et al.  Relationship between adherence level to statins, clinical issues and health-care costs in real-life clinical setting. , 2009, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[6]  Katherine M Flegal,et al.  Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. , 2012, JAMA.

[7]  N J Wald,et al.  Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies , 2009, BMJ : British Medical Journal.

[8]  E. Gregg,et al.  Secular Trends in Cardiovascular Disease Risk Factors According to Body Mass Index in US Adults , 2005 .

[9]  B. J. Gersh Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980–2000 , 2008 .

[10]  S. Harper,et al.  Social determinants and the decline of cardiovascular diseases: understanding the links. , 2011, Annual review of public health.

[11]  J. Gaziano,et al.  Simplifying the approach to the management of dyslipidemia. , 2009, JAMA.

[12]  Richard Kahn,et al.  The impact of prevention on reducing the burden of cardiovascular disease. , 2008, Circulation.

[13]  M. Roizen Forecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart Association , 2012 .

[14]  G. Colditz,et al.  Forecasting the Obesity Epidemic in the Aging U.S. Population , 2007, Obesity.

[15]  G A Beller,et al.  Demographics and cardiology, 1950-2050. , 2000, Journal of the American College of Cardiology.

[16]  T. Pearson,et al.  The prevention of cardiovascular disease: have we really made progress? , 2007, Health affairs.

[17]  A. Folsom,et al.  Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years' experience. , 1996, Journal of clinical epidemiology.

[18]  Donald M Berwick,et al.  The "Million Hearts" initiative--preventing heart attacks and strokes. , 2011, The New England journal of medicine.

[19]  D. Mozaffarian,et al.  Heart disease and stroke statistics--2012 update: a report from the American Heart Association. , 2012, Circulation.

[20]  Kirsten Bibbins-Domingo,et al.  Comparing Impact and Cost-Effectiveness of Primary Prevention Strategies for Lipid-Lowering , 2009, Annals of Internal Medicine.

[21]  S. Olshansky,et al.  A potential decline in life expectancy in the United States in the 21st century. , 2005, The New England journal of medicine.

[22]  F. Brancati,et al.  Socioeconomic Position and Cardiovascular Disease in Adults with and Without Diabetes: United States Trends, 1997–2005 , 2008, Journal of General Internal Medicine.

[23]  A. Folsom,et al.  Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease, 1987 to 1994. , 1998, The New England journal of medicine.

[24]  F. Hu,et al.  Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adults. , 2012, JAMA.

[25]  Alessandro Filippi,et al.  Adherence to Antihypertensive Medications and Cardiovascular Morbidity Among Newly Diagnosed Hypertensive Patients , 2009, Circulation.

[26]  L. Goldman,et al.  Adolescent overweight and future adult coronary heart disease. , 2007, The New England journal of medicine.

[27]  L. Green,et al.  Care Transformation , 2022 .

[28]  H. Krumholz,et al.  US cardiologist workforce from 1995 to 2007: modest growth, lasting geographic maldistribution especially in rural areas. , 2011, Health affairs.

[29]  N. Keenan,et al.  Trends in high levels of low-density lipoprotein cholesterol in the United States, 1999-2006. , 2009, JAMA.

[30]  W. Kannel,et al.  The Framingham Offspring Study. Design and preliminary data. , 1975, Preventive medicine.

[31]  Simon Capewell,et al.  Cardiovascular risk factor trends and potential for reducing coronary heart disease mortality in the United States of America. , 2010, Bulletin of the World Health Organization.

[32]  Daniel W. Jones,et al.  The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. , 2003, JAMA.

[33]  L. Goldman,et al.  Cost-Effectiveness of Statin Therapy for Primary Prevention in a Low-Cost Statin Era , 2011, Circulation.

[34]  K. Thorpe The rise in health care spending and what to do about it. , 2005, Health affairs.

[35]  John Simes,et al.  Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised controlled trials of statins (vol 366, pg 1267, 2005) , 2008 .

[36]  Cardiovascular Health Behavior and Health Factor Changes ( 1988 – 2008 ) and Projections to 2020 : Results From the National Health and Nutrition Examination Surveys , .

[37]  Susan T. Stewart,et al.  Forecasting the effects of obesity and smoking on U.S. life expectancy. , 2009, The New England journal of medicine.

[38]  K. Flegal,et al.  Evidence that the prevalence of childhood overweight is plateauing: data from nine countries. , 2011, International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity.

[39]  D. Mikhailidis,et al.  Beyond LDL-C – The Importance of Raising HDL-C , 2002, Current medical research and opinion.