The Temperature Sensitivity of the Cholinergic Responses of Cortical Neurons in the Guinea Pig Brain

Studies on slices of the parietal cortex of the guinea-pig brain showed that a change in temperature from 20°C to 36°C led to increases in responses to microintophoretic application of acetylcholine to individual nerve cells. The greatest changes occurred over two temperature ranges: 27–29°C and 34–36°C. Increases in the cholinergic response were accompanied by increases in the spontaneous activity of the neurons.

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