Gene expression profiling reveals a regulatory role for RORα and RORγ in phase I and phase II metabolism
暂无分享,去创建一个
J. Gimble | J. Collins | H. S. Kang | Sherry F. Grissom | Xiying Wu | A. Jetten | W. Xie | Hong Soon Kang | T. Wada | M. Angers | J. Beak
[1] W. Bremner,et al. Advances in male contraception. , 2008, Endocrine reviews.
[2] J. Mariani,et al. Rorα, a pivotal nuclear receptor for Purkinje neuron survival and differentiation: From development to ageing , 2008, The Cerebellum.
[3] J. Collins,et al. Modulatory Role for Retinoid-related Orphan Receptor α in Allergen-induced Lung Inflammation , 2006 .
[4] F. Gonzalez,et al. Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1α* , 2006, Journal of Biological Chemistry.
[5] Weimin He,et al. Nuclear Receptor Expression Links the Circadian Clock to Metabolism , 2006, Cell.
[6] D. Forrest,et al. Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta. , 2006, Molecular endocrinology.
[7] J. Collins,et al. NABP1, a novel RORγ-regulated gene encoding a single-stranded nucleic-acid-binding protein , 2006 .
[8] R. Evans,et al. A Novel Pregnane X Receptor-mediated and Sterol Regulatory Element-binding Protein-independent Lipogenic Pathway* , 2006, Journal of Biological Chemistry.
[9] Hongyue Dai,et al. Rosetta error model for gene expression analysis , 2006, Bioinform..
[10] Kim L R Brouwer,et al. Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[11] Sanjin Zvonic,et al. Characterization of peripheral circadian clocks in adipose tissues. , 2006, Diabetes.
[12] D. Mangelsdorf,et al. LXRS and FXR: the yin and yang of cholesterol and fat metabolism. , 2006, Annual review of physiology.
[13] C. Marohnic,et al. Cytochromes P450—A Family of Proteins and Scientists–Understanding their Relationships , 2006, Drug metabolism reviews.
[14] A. Jetten,et al. Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development. , 2006, Advances in developmental biology.
[15] F. Gonzalez,et al. Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. , 2006, The Journal of biological chemistry.
[16] J. Collins,et al. NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein. , 2006, The Biochemical journal.
[17] T. Kocarek,et al. Regulation of sulfotransferases by xenobiotic receptors. , 2005, Current drug metabolism.
[18] D. Moore,et al. CAR, the continuously advancing receptor, in drug metabolism and disease. , 2005, Current drug metabolism.
[19] D. Dixon,et al. Enhanced susceptibility of staggerer (RORalphasg/sg) mice to lipopolysaccharide-induced lung inflammation. , 2005, American journal of physiology. Lung cellular and molecular physiology.
[20] P. Strömstedt,et al. Identification of the human ApoAV gene as a novel RORα target gene , 2005 .
[21] Jacques Simard,et al. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family. , 2005, Endocrine reviews.
[22] P. Strömstedt,et al. Identification of the human ApoAV gene as a novel RORalpha target gene. , 2005, Biochemical and biophysical research communications.
[23] Jacques Simard,et al. Molecular Biology of the 3-Hydroxysteroid Dehydrogenase/5-4 Isomerase Gene Family , 2005 .
[24] A. Jetten. Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs). , 2004, Current drug targets. Inflammation and allergy.
[25] K. Feingold,et al. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. , 2004, American journal of physiology. Endocrinology and metabolism.
[26] G. Muscat,et al. RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. , 2004, The Journal of biological chemistry.
[27] B. Fournier,et al. Crystal Structure of the Human RORα Ligand Binding Domain in Complex with Cholesterol Sulfate at 2.2 Å* , 2004, Journal of Biological Chemistry.
[28] Yongwon Choi,et al. An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells , 2004, Nature Immunology.
[29] Benjamin D. Sachs,et al. RORα Coordinates Reciprocal Signaling in Cerebellar Development through Sonic hedgehog and Calcium-Dependent Pathways , 2003, Neuron.
[30] Hongbing Wang,et al. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors. , 2003, Current drug metabolism.
[31] F. Gonzalez,et al. Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice. , 2003, Biochemical pharmacology.
[32] Jean-Paul Renaud,et al. All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ , 2003, Nature Structural Biology.
[33] S. Kliewer. The nuclear pregnane X receptor regulates xenobiotic detoxification. , 2003, The Journal of nutrition.
[34] F. Gonzalez,et al. Protective Role of Hydroxysteroid Sulfotransferase in Lithocholic Acid-induced Liver Toxicity* , 2003, The Journal of Biological Chemistry.
[35] F. Gonzalez,et al. Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors. , 2003, Biochimica et biophysica acta.
[36] M. Geiser,et al. X-Ray Structure of the hRORα LBD at 1.63 Å , 2002 .
[37] C. Chauvet,et al. Retinoic acid receptor-related orphan receptor (ROR) alpha4 is the predominant isoform of the nuclear receptor RORalpha in the liver and is up-regulated by hypoxia in HepG2 human hepatoma cells. , 2002, The Biochemical journal.
[38] D. G. McCarver,et al. The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms. , 2002, The Journal of pharmacology and experimental therapeutics.
[39] M. Backlund,et al. High incidence of T-cell lymphomas in mice deficient in the retinoid-related orphan receptor RORgamma. , 2002, Cancer research.
[40] C. Chauvet,et al. Retinoic acid receptor-related orphan receptor (ROR) alpha4 is the predominant isoform of the nuclear receptor RORalpha in the liver and is up-regulated by hypoxia in HepG2 human hepatoma cells. , 2002, The Biochemical journal.
[41] A. Steinmetz,et al. X‐ray structure of the orphan nuclear receptor RORβ ligand‐binding domain in the active conformation , 2001, The EMBO journal.
[42] J. Mariani,et al. Transcriptional Regulation of Apolipoprotein C-III Gene Expression by the Orphan Nuclear Receptor RORα* , 2001, The Journal of Biological Chemistry.
[43] J. Mariani,et al. The orphan nuclear receptor RORα is a negative regulator of the inflammatory response , 2001 .
[44] J. Mariani,et al. The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response. , 2001, EMBO reports.
[45] F. Zhang,et al. Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis , 2000 .
[46] J. Mariani,et al. In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[47] A. Pierani,et al. Requirement for RORgamma in thymocyte survival and lymphoid organ development. , 2000, Science.
[48] D. Patel,et al. Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[49] F. Conquet,et al. Disruption of retinoid‐related orphan receptor β changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice , 1998, The EMBO journal.
[50] A. Medvedev,et al. Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[51] V. Giguère,et al. Orphan nuclear receptor RORα-deficient mice display the cerebellar defects of staggerer , 1998, Mechanisms of Development.
[52] J. Kapfhammer,et al. The ExDression Pattern of the Orphan Nuclear Receptor RORβ in the Developing and Adult Rat Nervous System Suggests a Role in the Processing of Sensory Information and in Circadian Rhythm , 1997, The European journal of neuroscience.
[53] J. Auwerx,et al. Transcriptional Regulation of Apolipoprotein A-I Gene Expression by the Nuclear Receptor RORα* , 1997, The Journal of Biological Chemistry.
[54] V. Giguère,et al. Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element. , 1996, Gene.
[55] B. Birren,et al. Disruption of the nuclear hormone receptor RORα in staggerer mice , 1996, Nature.
[56] B. Birren,et al. Disruption of the nuclear hormone receptor RORalpha in staggerer mice. , 1996, Nature.
[57] N. Copeland,et al. The orphan nuclear receptor ROR alpha (RORA) maps to a conserved region of homology on human chromosome 15q21-q22 and mouse chromosome 9. , 1995, Genomics.
[58] A. Jetten,et al. ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle. , 1994, Biochemical and biophysical research communications.