Collinearity in Mouse Limbs Genes HoxD A Switch Between Topological Domains Underlies

, (2013); 340 Science et al. Guillaume Andrey Collinearity in Mouse Limbs Genes HoxD A Switch Between Topological Domains Underlies This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission to republish or repurpose articles or portions of articles ): April 22, 2014 www.sciencemag.org (this information is current as of The following resources related to this article are available online at http://www.sciencemag.org/content/340/6137/1234167.full.html version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/content/suppl/2013/06/06/340.6137.1234167.DC1.html can be found at: Supporting Online Material http://www.sciencemag.org/content/340/6137/1234167.full.html#related found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.sciencemag.org/content/340/6137/1234167.full.html#ref-list-1 , 21 of which can be accessed free: cites 51 articles This article http://www.sciencemag.org/content/340/6137/1234167.full.html#related-urls 7 articles hosted by HighWire Press; see: cited by This article has been http://www.sciencemag.org/cgi/collection/development Development subject collections: This article appears in the following

[1]  Y. Hérault,et al.  Engineering chromosomes in mice through targeted meiotic recombination (TAMERE) , 1998, Nature Genetics.

[2]  J. Rougemont,et al.  The Dynamic Architecture of Hox Gene Clusters , 2011, Science.

[3]  James A. Cuff,et al.  A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.

[4]  D. Duboule,et al.  The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes. , 2001, Developmental biology.

[5]  E. Furlong,et al.  Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development , 2012, Nature Genetics.

[6]  D. Duboule,et al.  Spatially restricted domains of homeo-gene transcripts in mouse embryos: relation to a segmented body plan , 1988 .

[7]  R. Young,et al.  Histone H3K27ac separates active from poised enhancers and predicts developmental state , 2010, Proceedings of the National Academy of Sciences.

[8]  Denis Duboule,et al.  Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation , 1989, Nature.

[9]  S. Antonarakis,et al.  A Systematic Enhancer Screen Using Lentivector Transgenesis Identifies Conserved and Non-Conserved Functional Elements at the Olig1 and Olig2 Locus , 2010, PloS one.

[10]  Kristian Helin,et al.  Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. , 2006, Genes & development.

[11]  R. Krumlauf,et al.  The murine and Drosophila homeobox gene complexes have common features of organization and expression , 1989, Cell.

[12]  A. Kuroiwa,et al.  Homeobox gene expression correlated with the bifurcation process of limb cartilage development , 1991, Nature.

[13]  J. Sedat,et al.  Spatial partitioning of the regulatory landscape of the X-inactivation centre , 2012, Nature.

[14]  M. Kerszberg,et al.  Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness. , 2008, Genes & development.

[15]  F. Rijli,et al.  Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development , 2010, Development.

[16]  Wouter de Laat,et al.  A Regulatory Archipelago Controls Hox Genes Transcription in Digits , 2011, Cell.

[17]  R. Maeda,et al.  The ABC of the BX-C: the bithorax complex explained , 2006, Development.

[18]  J. Zeitlinger,et al.  Polycomb complexes repress developmental regulators in murine embryonic stem cells , 2006, Nature.

[19]  C. Tabin,et al.  Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud , 1994, Cell.

[20]  D. Duboule,et al.  A regulatory 'landscape effect' over the HoxD cluster. , 2011, Developmental biology.

[21]  Eric S. Lander,et al.  Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse , 2005, Cell.

[22]  Jesse R. Dixon,et al.  Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions , 2012, Nature.

[23]  David Baltimore,et al.  Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors , 2002, Science.

[24]  D. Duboule,et al.  Control of Hoxd genes' collinearity during early limb development. , 2006, Developmental cell.

[25]  Denis Duboule,et al.  The rise and fall of Hox gene clusters , 2007, Development.

[26]  C. Tabin,et al.  Analysis of Hox gene expression in the chick limb bud. , 1996, Development.

[27]  D. Duboule,et al.  The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. , 1989, The EMBO journal.

[28]  Y. Hérault,et al.  Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes. , 1997, Development.

[29]  K. Mechtler,et al.  Epigenetic Temporal Control of Mouse Hox Genes in Vivo , 2009 .

[30]  Lee E. Edsall,et al.  A map of the cis-regulatory sequences in the mouse genome , 2012, Nature.

[31]  S. Mundlos,et al.  Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. , 2010, The Journal of clinical investigation.

[32]  Michael Q. Zhang,et al.  Combinatorial patterns of histone acetylations and methylations in the human genome , 2008, Nature Genetics.

[33]  Megan F. Cole,et al.  Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells , 2006, Cell.

[34]  J. Changeux,et al.  50th anniversary of the word “allosteric” , 2011, Protein science : a publication of the Protein Society.

[35]  Ryan A. Flynn,et al.  A unique chromatin signature uncovers early developmental enhancers in humans , 2011, Nature.

[36]  D. Duboule,et al.  Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes , 2005, Nature Genetics.

[37]  Lewis Wolpert,et al.  Rethinking the proximodistal axis of the vertebrate limb in the molecular era. , 2007, Genes & development.

[38]  E. Lewis.  A gene complex controlling segmentation in Drosophila , 1978, Nature.

[39]  D. Duboule,et al.  Organizing Axes in Time and Space; 25 Years of Colinear Tinkering , 2003, Science.