DNAzyme tunable lead(II) gating based on ion-track etched conical nanochannels.

A simple biomimetic ionic gate has been developed by modifying lead(II) ion responsive DNAzymes onto the inner surface of ion-etched polymer nanochannels.

[1]  Jinghong Li,et al.  Small-molecule triggered cascade enzymatic catalysis in hour-glass shaped nanochannel reactor for glucose monitoring. , 2014, Analytical chemistry.

[2]  Intracellular release of anticancer agents from a hollow silica nanocontainer with glutathione-responsive cyclodextrin gatekeepers , 2014 .

[3]  C. Zukoski,et al.  STUDY OF ANION ADSORPTION AT THE GOLD-AQUEOUS SOLUTION INTERFACE BY ATOMIC-FORCE MICROSCOPY , 1994 .

[4]  Philip C Biggin,et al.  Ion channel gating: insights via molecular simulations , 2003, FEBS letters.

[5]  Jin Zhai,et al.  A biomimetic mercury(II)-gated single nanochannel. , 2013, Chemical communications.

[6]  J. Osterloh,et al.  Pharmacokinetics of CaNa2EDTA and chelation of lead in renal failure , 1986, Clinical pharmacology and therapeutics.

[7]  Yi Lu,et al.  Improving fluorescent DNAzyme biosensors by combining inter- and intramolecular quenchers. , 2003, Analytical chemistry.

[8]  M. Majd,et al.  Diagnosis of acute pyelonephritis in children: comparison of sonography and 99mTc-DMSA scintigraphy. , 1991, AJR. American journal of roentgenology.

[9]  Jie Zheng,et al.  Mimicking the binding and unbinding of Fe3+ with transferrin using a single biomimetic nanochannel. , 2013, Chemical communications.

[10]  N. Goldraich,et al.  Urography versus DMSA scan in children with vesicoureteric reflux , 2004, Pediatric Nephrology.

[11]  Zuzanna S Siwy,et al.  Calcium-induced voltage gating in single conical nanopores. , 2006, Nano letters.

[12]  C. R. Martin,et al.  Developing synthetic conical nanopores for biosensing applications. , 2007, Molecular bioSystems.

[13]  P. Bijur,et al.  L-line x-ray fluorescence of cortical bone lead compared with the CaNa2EDTA test in lead-toxic children: public health implications. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Jin Zhai,et al.  Bioinspired Smart Gating of Nanochannels Toward Photoelectric‐Conversion Systems , 2010, Advanced materials.

[15]  Wei Guo,et al.  A biomimetic zinc activated ion channel. , 2010, Chemical communications.

[16]  Xu Hou,et al.  A biomimetic potassium responsive nanochannel: G-quadruplex DNA conformational switching in a synthetic nanopore. , 2009, Journal of the American Chemical Society.

[17]  Bob Eisenberg.  Ionic Channels in Biological Membranes: Natural Nanotubes , 1998 .

[18]  Boris Martinac,et al.  Open channel structure of MscL and the gating mechanism of mechanosensitive channels , 2002, Nature.

[19]  Z. Siwy,et al.  Ion‐Current Rectification in Nanopores and Nanotubes with Broken Symmetry , 2006 .

[20]  Lei Jiang,et al.  A bio-inspired, sensitive, and selective ionic gate driven by silver (I) ions. , 2015, Small.

[21]  L. Fruk,et al.  Tuning nanopore surface polarity and rectification properties through enzymatic hydrolysis inside nanoconfined geometries. , 2013, Chemical communications.