Sodium butyrate potentiates insulin secretion from rat islets at the expense of compromised expression of β cell identity genes

[1]  C. Newgard,et al.  Mechanisms controlling pancreatic islet cell function in insulin secretion , 2021, Nature Reviews Molecular Cell Biology.

[2]  A. Mika,et al.  Sample Preparation Methods for Lipidomics Approaches Used in Studies of Obesity , 2020, Molecules.

[3]  Zu-hua Gao,et al.  Controversial Roles of Gut Microbiota-Derived Short-Chain Fatty Acids (SCFAs) on Pancreatic β-Cell Growth and Insulin Secretion , 2020, International journal of molecular sciences.

[4]  H. Lickert,et al.  β-Cell Maturation and Identity in Health and Disease , 2019, International journal of molecular sciences.

[5]  G. Frost,et al.  Short chain fatty acids stimulate insulin secretion and reduce apoptosis in mouse and human islets in vitro: Role of free fatty acid receptor 2 , 2018, Diabetes, obesity & metabolism.

[6]  Tianwen Gao,et al.  Metabolic Signaling into Chromatin Modifications in the Regulation of Gene Expression , 2018, International journal of molecular sciences.

[7]  Haitao Li,et al.  Beyond histone acetylation-writing and erasing histone acylations. , 2018, Current opinion in structural biology.

[8]  Jae-Hyung Park,et al.  Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells. , 2018, Biochemical and biophysical research communications.

[9]  Jia Li,et al.  The Landscape of Histone Modifications in a High-Fat Diet-Induced Obese (DIO) Mouse Model* , 2017, Molecular & Cellular Proteomics.

[10]  E. Chambers,et al.  The diet‐derived short chain fatty acid propionate improves beta‐cell function in humans and stimulates insulin secretion from human islets in vitro , 2017, Diabetes, obesity & metabolism.

[11]  J. Delcour,et al.  Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study , 2017, The Journal of physiology.

[12]  Di Zhang,et al.  Metabolic regulation of gene expression through histone acylations , 2016, Nature Reviews Molecular Cell Biology.

[13]  K. Lemaire,et al.  Disallowed and Allowed Gene Expression: Two Faces of Mature Islet Beta Cells. , 2016, Annual review of nutrition.

[14]  R. Roeder,et al.  Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters , 2016, Molecular cell.

[15]  A. Margolles,et al.  Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health , 2016, Front. Microbiol..

[16]  Ellen E. Blaak,et al.  Short-chain fatty acids in control of body weight and insulin sensitivity , 2015, Nature Reviews Endocrinology.

[17]  B. Wicksteed,et al.  An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion. , 2015, Molecular endocrinology.

[18]  G. Rutter,et al.  Pancreatic β-cell identity, glucose sensing and the control of insulin secretion. , 2015, The Biochemical journal.

[19]  Stefan Offermanns,et al.  Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes , 2015, Nature Medicine.

[20]  Satoru Takahashi,et al.  MafA is critical for maintenance of the mature beta cell phenotype in mice , 2015, Diabetologia.

[21]  G. Jena,et al.  Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. , 2014, Chemico-biological interactions.

[22]  S. Offermanns.  Free fatty acid (FFA) and hydroxy carboxylic acid (HCA) receptors. , 2014, Annual review of pharmacology and toxicology.

[23]  Mark I. McCarthy,et al.  Pancreatic islet enhancer clusters enriched in type 2 diabetes risk–associated variants , 2013, Nature Genetics.

[24]  C. Mackay,et al.  The role of short-chain fatty acids in health and disease. , 2014, Advances in immunology.

[25]  Patrice D Cani,et al.  Gut microbiota, enteroendocrine functions and metabolism. , 2013, Current opinion in pharmacology.

[26]  M. Sander,et al.  Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells. , 2013, Cell reports.

[27]  M. Prentki,et al.  Metabolic signaling in fuel-induced insulin secretion. , 2013, Cell metabolism.

[28]  G. Rutter,et al.  When less is more: the forbidden fruits of gene repression in the adult β‐cell , 2013, Diabetes, obesity & metabolism.

[29]  M. Marra,et al.  Identification and analysis of murine pancreatic islet enhancers , 2013, Diabetologia.

[30]  N. Billestrup,et al.  Histone Deacetylase (HDAC) Inhibition as a Novel Treatment for Diabetes Mellitus , 2011, Molecular medicine.

[31]  Lieven Thorrez,et al.  Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. , 2011, Genome research.

[32]  R. Young,et al.  Histone H3K27ac separates active from poised enhancers and predicts developmental state , 2010, Proceedings of the National Academy of Sciences.

[33]  K. Kaestner,et al.  Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. , 2010, Cell metabolism.

[34]  G. Rutter,et al.  Identification of genes selectively disallowed in the pancreatic islet , 2010, Islets.

[35]  T. Tuomi,et al.  Clinical Heterogeneity in Monogenic Diabetes Caused by Mutations in the Glucokinase Gene (GCK-MODY) , 2009, Diabetes Care.

[36]  W. Cefalu,et al.  Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice , 2009, Diabetes.

[37]  Nathan L. Vanderford,et al.  Glucose regulation of insulin gene expression in pancreatic beta-cells. , 2008, The Biochemical journal.

[38]  R. Scharfmann,et al.  Histone Deacetylase Inhibitors Modify Pancreatic Cell Fate Determination and Amplify Endocrine Progenitors , 2008, Molecular and Cellular Biology.

[39]  J. Henquin,et al.  Overnight Culture Unmasks Glucose-induced Insulin Secretion in Mouse Islets Lacking ATP-sensitive K+ Channels by Improving the Triggering Ca2+ Signal* , 2007, Journal of Biological Chemistry.

[40]  A. Mosley,et al.  Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. , 2004, Molecular endocrinology.

[41]  R. Mirmira,et al.  Covalent Histone Modifications Underlie the Developmental Regulation of Insulin Gene Transcription in Pancreatic β Cells* , 2003, Journal of Biological Chemistry.

[42]  Masataka Harada,et al.  Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40 , 2003, Nature.

[43]  K. Kataoka,et al.  MafA Is a Glucose-regulated and Pancreatic β-Cell-specific Transcriptional Activator for the Insulin Gene* , 2002, The Journal of Biological Chemistry.

[44]  R. Stein,et al.  Insulin Gene Transcription Is Mediated by Interactions between the p300 Coactivator and PDX-1, BETA2, and E47 , 2002, Molecular and Cellular Biology.

[45]  M. Komatsu,et al.  Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose. , 1999, Diabetes.

[46]  G. Boden,et al.  Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects. , 1998, Diabetes.

[47]  C. Newgard,et al.  β-Cell Function in Normal Rats Made Chronically Hyperleptinemic by Adenovirus-Leptin Gene Therapy , 1997, Diabetes.

[48]  J. McGarry,et al.  The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. , 1997, The Journal of clinical investigation.

[49]  Lawrence A Leiter,et al.  Time of day and glucose tolerance status affect serum short-chain fatty acid concentrations in humans. , 1997, Metabolism: clinical and experimental.

[50]  J. Leahy,et al.  Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids , 1997, Diabetologia.

[51]  J. McGarry,et al.  Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. , 1996, The Journal of clinical investigation.

[52]  E. Oetjen,et al.  Distinct properties of the cAMP-responsive element of the rat insulin I gene. , 1994, The Journal of biological chemistry.

[53]  S. Christakos,et al.  1,25-Dihydroxyvitamin D3 and pancreatic beta-cell function: vitamin D receptors, gene expression, and insulin secretion. , 1994, Endocrinology.

[54]  J. Philippe,et al.  Functional characterization of a cAMP-responsive element of the rat insulin I gene. , 1990, The Journal of biological chemistry.

[55]  S. Singh,et al.  Effect of ethanol and its metabolites on glucose mediated insulin release from isolated islets of rats. , 1979, Metabolism: clinical and experimental.

[56]  D. Steinberg,et al.  Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect. , 1973, The Journal of clinical investigation.