Design and Comparative Performance of a Robust Lung Auscultation System for Noisy Clinical Settings

Chest auscultation is a widely used clinical tool for respiratory disease detection. The stethoscope has undergone a number of transformative enhancements since its invention, including the introduction of electronic systems in the last two decades. Nevertheless, stethoscopes remain riddled with a number of issues that limit their signal quality and diagnostic capability, rendering both traditional and electronic stethoscopes unusable in noisy or non-traditional environments (e.g., emergency rooms, rural clinics, ambulatory vehicles). This work outlines the design and validation of an advanced electronic stethoscope that dramatically reduces external noise contamination through hardware redesign and real-time, dynamic signal processing. The proposed system takes advantage of an acoustic sensor array, an external facing microphone, and on-board processing to perform adaptive noise suppression. The proposed system is objectively compared to six commercially-available acoustic and electronic devices in varying levels of simulated noisy clinical settings and quantified using two metrics that reflect perceptual audibility and statistical similarity, normalized covariance measure (NCM) and magnitude squared coherence (MSC). The analyses highlight the major limitations of current stethoscopes and the significant improvements the proposed system makes in challenging settings by minimizing both distortion of lung sounds and contamination by ambient noise.

[1]  Mounya Elhilali,et al.  A multiresolution analysis for detection of abnormal lung sounds , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[2]  Robert P. Jackman,et al.  Noise Reduction Stethoscope For United States Navy Application , 2000 .

[3]  Raymond L. Goldsworthy,et al.  Analysis of speech-based Speech Transmission Index methods with implications for nonlinear operations. , 2004, The Journal of the Acoustical Society of America.

[4]  Christophe Verjus,et al.  Towards an unsupervised device for the diagnosis of childhood pneumonia in low resource settings: Automatic segmentation of respiratory sounds , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[5]  John A. Rogers,et al.  Highly Sensitive Skin‐Mountable Strain Gauges Based Entirely on Elastomers , 2012 .

[6]  Jiarui Li,et al.  Wheeze Detection Algorithm Based on Spectrogram Analysis , 2015, 2015 8th International Symposium on Computational Intelligence and Design (ISCID).

[7]  S B Patel,et al.  An adaptive noise reduction stethoscope for auscultation in high noise environments. , 1998, The Journal of the Acoustical Society of America.

[8]  C. Swinburne Sound effects. , 2000, Nursing standard (Royal College of Nursing (Great Britain) : 1987).

[9]  D. E. Weston,et al.  The Theory of the Propagation of Plane Sound Waves in Tubes , 1953 .

[10]  Noman Qaid Al-Naggar A new method of lung sounds filtering using modulated least mean square—Adaptive noise cancellation , 2013 .

[11]  Mounya Elhilali,et al.  Computerized Lung Sound Screening for Pediatric Auscultation in Noisy Field Environments , 2018, IEEE Transactions on Biomedical Engineering.

[12]  Mounya Elhilali,et al.  Adaptive Noise Suppression of Pediatric Lung Auscultations With Real Applications to Noisy Clinical Settings in Developing Countries , 2015, IEEE Transactions on Biomedical Engineering.

[13]  S. Taylor,et al.  An electronic stethoscope. , 1956, Lancet.

[14]  Duane S Cronin,et al.  High strain rate compressive properties of bovine muscle tissue determined using a split Hopkinson bar apparatus. , 2006, Journal of biomechanics.

[15]  José Antonio Fiz,et al.  Automatic Differentiation of Normal and Continuous Adventitious Respiratory Sounds Using Ensemble Empirical Mode Decomposition and Instantaneous Frequency , 2016, IEEE Journal of Biomedical and Health Informatics.

[16]  Rajesh Rajamani,et al.  Accelerometer-Based Acoustic Control: Enabling Auscultation on a Black Hawk Helicopter , 2017, IEEE/ASME Transactions on Mechatronics.

[17]  Y. Yokota,et al.  Propagation Route Estimation of Heart Sound through Simultaneous Multi-site Recording on the Chest Wall , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[18]  Garrett Nelson,et al.  Stethoscope Design for Auscultation in High Noise Environments , 2015 .

[19]  Mounya Elhilali,et al.  Validation of Auscultation Technologies using Objective and Clinical Comparisons , 2020, 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

[20]  Yi Hu,et al.  Objective measures for predicting speech intelligibility in noisy conditions based on new band-importance functions. , 2009, The Journal of the Acoustical Society of America.

[21]  Shoichi Matsunaga,et al.  Robust classification between normal and abnormal lung sounds using adventitious-sound and heart-sound models , 2014, 2014 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP).

[22]  Rajesh Rajamani,et al.  Noise control challenges for auscultation on medical evacuation helicopters , 2014 .

[23]  Robert H. Gilman,et al.  Developing a Reference of Normal Lung Sounds in Healthy Peruvian Children , 2014, Lung.

[24]  M. A. Chavez,et al.  Building a Prediction Model for Radiographically Confirmed Pneumonia in Peruvian Children , 2018, Chest.

[25]  P. Alapat,et al.  Validation of Automatic Wheeze Detection in Patients with Obstructed Airways and in Healthy Subjects , 2008, The Journal of asthma : official journal of the Association for the Care of Asthma.

[26]  G. Kirchhoff,et al.  Ueber den Einfluss der Wärmeleitung in einem Gase auf die Schallbewegung , 1868 .

[27]  M L Fackler,et al.  Ordnance Gelatin for Ballistic Studies: Detrimental Effect of Excess Heat Used in Gelatin Preparation , 1988, The American journal of forensic medicine and pathology.

[28]  Lukasz J. Nowak,et al.  Acoustic characterization of stethoscopes using auscultation sounds as test signals. , 2017, The Journal of the Acoustical Society of America.

[29]  J. Richman,et al.  Physiological time-series analysis using approximate entropy and sample entropy. , 2000, American journal of physiology. Heart and circulatory physiology.

[30]  Philipos C. Loizou,et al.  Speech Enhancement: Theory and Practice , 2007 .

[31]  R. Spagnolo,et al.  Surface distribution of crackling sounds , 1988, IEEE Transactions on Biomedical Engineering.

[32]  Maria Deloria-Knoll,et al.  The Pneumonia Etiology Research for Child Health Project: A 21st Century Childhood Pneumonia Etiology Study , 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[33]  Evidence Summaries Revised WHO classification and treatment of childhood pneumonia at health facilities , 2014 .

[34]  Y. Karplyuk,et al.  Application of bispectrum analysis to lung sounds in patients with the chronic obstructive lung disease , 2014, 2014 IEEE 34th International Scientific Conference on Electronics and Nanotechnology (ELNANO).

[35]  A Sakula,et al.  R T H Laënnec 1781--1826 his life and work: a bicentenary appreciation. , 1981, Thorax.

[36]  Thomas Ferkol,et al.  The global burden of respiratory disease. , 2014, Annals of the American Thoracic Society.