A standard system phantom for magnetic resonance imaging

A standard MRI system phantom has been designed and fabricated to assess scanner performance, stability, comparability and assess the accuracy of quantitative relaxation time imaging. The phantom is unique in having traceability to the International System of Units, a high level of precision, and monitoring by a national metrology institute. Here, we describe the phantom design, construction, imaging protocols, and measurement of geometric distortion, resolution, slice profile, signal‐to‐noise ratio (SNR), proton‐spin relaxation times, image uniformity and proton density.

[1]  S. Russek,et al.  MRI‐visible liquid crystal thermometer , 2020, Magnetic resonance in medicine.

[2]  Andrew Dienstfrey,et al.  Assessing effects of scanner upgrades for clinical studies , 2019, Journal of magnetic resonance imaging : JMRI.

[3]  S. Russek,et al.  Magnetic Resonance Imaging Biomarker Calibration Service: Proton Spin Relaxation Times , 2018 .

[4]  Wei Huang,et al.  Accuracy, repeatability, and interplatform reproducibility of T1 quantification methods used for DCE‐MRI: Results from a multicenter phantom study , 2018, Magnetic resonance in medicine.

[5]  Mara Cercignani,et al.  Quantitative MRI of the Brain : Principles of Physical Measurement, Second edition , 2018 .

[6]  C. Jack,et al.  Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom , 2018, Magnetic resonance in medicine.

[7]  M. Griswold,et al.  Repeatability of magnetic resonance fingerprinting T1 and T2 estimates assessed using the ISMRM/NIST MRI system phantom , 2017, Magnetic resonance in medicine.

[8]  N. Hylton,et al.  Design of a breast phantom for quantitative MRI , 2016, Journal of magnetic resonance imaging : JMRI.

[9]  L. V. van Vliet,et al.  Feasibility of a fast method for B1-inhomogeneity correction for FSPGR sequences. , 2015, Magnetic resonance imaging.

[10]  J. Finsterbusch,et al.  Optimization and Validation of Methods for Mapping of the Radiofrequency Transmit Field at 3T , 2010, Magnetic resonance in medicine.

[11]  Norbert Schuff,et al.  Measurement of MRI scanner performance with the ADNI phantom. , 2009, Medical physics.

[12]  A. Laaksonen,et al.  Extensive NMRD studies of Ni(II) salt solutions in water and water-glycerol mixtures. , 2008, Journal of magnetic resonance.

[13]  Ram D. Sriram,et al.  Imaging as a Biomarker: Standards for Change Measurements in Therapy workshop summary. , 2008, Academic radiology.

[14]  Jozef Kowalewski,et al.  Nuclear spin relaxation in liquids : theory, experiments, and applications , 2006 .

[15]  Huanzhou Yu,et al.  Relaxation times of breast tissue at 1.5T and 3T measured using IDEAL , 2006, Journal of magnetic resonance imaging : JMRI.

[16]  Michael B. Smith,et al.  Central brightening due to constructive interference with, without, and despite dielectric resonance , 2005, Journal of magnetic resonance imaging : JMRI.

[17]  P. Tofts PD: Proton Density of Tissue Water , 2004 .

[18]  Peter Andersen,et al.  In vivo 1H2O T  †2 measurement in the human occipital lobe at 4T and 7T by Carr‐Purcell MRI: Detection of microscopic susceptibility contrast , 2002, Magnetic resonance in medicine.

[19]  P. Kingsley,et al.  Methods of measuring spin-lattice ( T 1 ) relaxation times: an annotated bibliography , 1999 .

[20]  F. Ye,et al.  Estimation of the iron concentration in excised gray matter by means of proton relaxation measurements , 1996, Magnetic resonance in medicine.

[21]  P. Fatouros,et al.  An MRI phantom material for quantitative relaxometry , 1987, Magnetic resonance in medicine.

[22]  J. Gore,et al.  Errors in the measurements of T2 using multiple‐echo MRI techniques. II. Effects of static field inhomogeneity , 1986, Magnetic resonance in medicine.

[23]  J C Gore,et al.  Errors in the measurements of T2 using multiple‐echo MRI techniques. I. Effects of radiofrequency pulse imperfections , 1986, Magnetic resonance in medicine.

[24]  R. Vold,et al.  Errors in measurements of transverse relaxation rates , 1973 .

[25]  H. Carr,et al.  The Principles of Nuclear Magnetism , 1961 .

[26]  S. Russek Magnetic Resonance Imaging Biomarker Calibration Service: , 2022 .

[27]  Alain Lalande,et al.  What are normal relaxation times of tissues at 3 T? , 2017, Magnetic resonance imaging.

[28]  Michael Jerosch-Herold,et al.  T1 Mapping: Basic Techniques and Clinical Applications. , 2016, JACC. Cardiovascular imaging.

[29]  Rudolf Stollberger,et al.  RF-field mapping in vivo , 1988 .