Gyrocardiography: A New Non-invasive Monitoring Method for the Assessment of Cardiac Mechanics and the Estimation of Hemodynamic Variables

Gyrocardiography (GCG) is a new non-invasive technique for assessing heart motions by using a sensor of angular motion – gyroscope – attached to the skin of the chest. In this study, we conducted simultaneous recordings of electrocardiography (ECG), GCG, and echocardiography in a group of subjects consisting of nine healthy volunteer men. Annotation of underlying fiducial points in GCG is presented and compared to opening and closing points of heart valves measured by a pulse wave Doppler. Comparison between GCG and synchronized tissue Doppler imaging (TDI) data shows that the GCG signal is also capable of providing temporal information on the systolic and early diastolic peak velocities of the myocardium. Furthermore, time intervals from the ECG Q-wave to the maximum of the integrated GCG (angular displacement) signal and maximal myocardial strain curves obtained by 3D speckle tracking are correlated. We see GCG as a promising mechanical cardiac monitoring tool that enables quantification of beat-by-beat dynamics of systolic time intervals (STI) related to hemodynamic variables and myocardial contractility.

[1]  Kouhyar Tavakolian,et al.  Ballistocardiography and Seismocardiography: A Review of Recent Advances , 2015, IEEE Journal of Biomedical and Health Informatics.

[2]  Daniel McDuff,et al.  Biophone: Physiology monitoring from peripheral smartphone motions , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[3]  Arye Nehorai,et al.  A Hidden Markov Model for Seismocardiography , 2017, IEEE Transactions on Biomedical Engineering.

[4]  B S BOZHENKO,et al.  [Seismocardiography--a new method in the study of functional conditions of the heart]. , 1961, Terapevticheskii arkhiv.

[5]  Zhi-Hong Mao,et al.  Estimation of heart rate from a chest-worn inertial measurement unit , 2015, 2015 International Symposium on Bioelectronics and Bioinformatics (ISBB).

[6]  F. Rizzo,et al.  Wearable seismocardiography: Towards a beat-by-beat assessment of cardiac mechanics in ambulant subjects , 2013, Autonomic Neuroscience.

[7]  Laura Cercenelli,et al.  First Experimental Evaluation of Cardiac Apex Rotation with an Epicardial Coriolis Force Sensor , 2005, ASAIO journal.

[8]  Kouhyar Tavakolian,et al.  Seismocardiography: Past, present and future , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[9]  A. Støylen,et al.  Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging. , 2006, Journal of the American College of Cardiology.

[10]  Omer T. Inan,et al.  Ballistocardiogram: Mechanism and Potential for Unobtrusive Cardiovascular Health Monitoring , 2016, Scientific Reports.

[11]  Tero Koivisto,et al.  A smartphone-only solution for detecting indications of acute myocardial infarction , 2017, 2017 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI).

[12]  Frank E. Rademakers,et al.  Dissociation Between Left Ventricular Untwisting and Filling: Accentuation by Catecholamines , 1992, Circulation.

[13]  Carlo Menon,et al.  Automatic and Robust Delineation of the Fiducial Points of the Seismocardiogram Signal for Non-invasive Estimation of Cardiac Time Intervals. , 2016, IEEE transactions on bio-medical engineering.

[14]  I. Starr,et al.  STUDIES ON THE ESTIMATION OF CARDIAC OUPTUT IN MAN, AND OF ABNORMALITIES IN CARDIAC FUNCTION, FROM THE HEART'S RECOIL AND THE BLOOD'S IMPACTS; THE BALLISTOCARDIOGRAM , 1939 .

[15]  M. Cecchini,et al.  Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease , 2016, Scientific Reports.

[16]  Rafael Beyar,et al.  An optical device to measure the dynamics of apex rotation of the left ventricle , 1992 .

[17]  D. Holdstock Past, present--and future? , 2005, Medicine, conflict, and survival.

[18]  D M Salerno,et al.  Seismocardiographic changes associated with obstruction of coronary blood flow during balloon angioplasty. , 1991, The American journal of cardiology.

[19]  Kouhyar Tavakolian,et al.  Myocardial contractility: A seismocardiography approach , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[20]  Tero Koivisto,et al.  Heart rate variability estimation with joint accelerometer and gyroscope sensing , 2016, 2016 Computing in Cardiology Conference (CinC).

[21]  James M. Rehg,et al.  BioGlass: Physiological parameter estimation using a head-mounted wearable device , 2014, 2014 4th International Conference on Wireless Mobile Communication and Healthcare - Transforming Healthcare Through Innovations in Mobile and Wireless Technologies (MOBIHEALTH).

[22]  Chenxi Yang,et al.  Annotation of seismocardiogram using gyroscopic recordings , 2016, 2016 IEEE Biomedical Circuits and Systems Conference (BioCAS).

[23]  John M Forrester On the reason of the movement of the muscles , 2001, Medical History.

[24]  Eero Lehtonen,et al.  A real-time approach for heart rate monitoring using a Hilbert transform in seismocardiograms , 2016, Physiological measurement.

[25]  Rafael Beyar,et al.  An optical device to measure the dynamics of apex rotation of the left ventricle , 1992, 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[26]  H. Dodge,et al.  The Relationship of Alterations in Systolic Time Intervals to Ejection Fraction in Patients with Cardiac Disease , 1970, Circulation.

[27]  K. Radermacher,et al.  Simplified detection of myocardial ischemia by seismocardiography , 2013, Herz.

[28]  Carlo Menon,et al.  Automatic and Robust Delineation of the Fiducial Points of the Seismocardiogram Signal for Noninvasive Estimation of Cardiac Time Intervals , 2017, IEEE Transactions on Biomedical Engineering.

[29]  Eero Lehtonen,et al.  A miniaturized MEMS motion processing system for nuclear medicine imaging applications , 2016, 2016 Computing in Cardiology Conference (CinC).

[30]  T. Tekten,et al.  Novel Approach to Measure Myocardial Performance Index: Pulsed‐Wave Tissue Doppler Echocardiography , 2003, Echocardiography.

[31]  Kouhyar Tavakolian,et al.  Automatic Annotation of Seismocardiogram With High-Frequency Precordial Accelerations , 2015, IEEE Journal of Biomedical and Health Informatics.

[32]  Eero Lehtonen,et al.  Gyrocardiography: A new non-invasive approach in the study of mechanical motions of the heart. Concept, method and initial observations , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[33]  Pierre-François Migeotte,et al.  Multi-dimensional Kineticardiography a New Approach for Wearable Cardiac Monitoring Through Body Acceleration Recordings , 2016 .

[34]  Richard D. White,et al.  Assessment of Left Ventricular Torsional Deformation by Doppler Tissue Imaging: Validation Study With Tagged Magnetic Resonance Imaging , 2004, Circulation.

[35]  Daniel McDuff,et al.  BioInsights: Extracting personal data from “Still” wearable motion sensors , 2015, 2015 IEEE 12th International Conference on Wearable and Implantable Body Sensor Networks (BSN).

[36]  Laura Cercenelli,et al.  Effect of Right Ventricular Pacing on Cardiac Apex Rotation Assessed by a Gyroscopic Sensor , 2007, ASAIO journal.

[37]  G. Gelinck,et al.  Reconfigurable Complementary Logic Circuits with Ambipolar Organic Transistors , 2016, Scientific Reports.

[38]  Willis J. Tompkins,et al.  A Real-Time QRS Detection Algorithm , 1985, IEEE Transactions on Biomedical Engineering.

[39]  J W Gordon,et al.  Certain Molar Movements of the Human Body produced by the Circulation of the Blood. , 1877, Journal of anatomy and physiology.

[40]  E. Fosse,et al.  Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor. , 2014, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[41]  Eero Lehtonen,et al.  A miniaturized low power biomedical sensor node for clinical research and long term monitoring of cardiovascular signals , 2017, 2017 IEEE International Symposium on Circuits and Systems (ISCAS).

[42]  Shuvo Roy,et al.  A Wearable Patch to Enable Long-Term Monitoring of Environmental, Activity and Hemodynamics Variables , 2016, IEEE Transactions on Biomedical Circuits and Systems.

[43]  E. McVeigh,et al.  Three-dimensional systolic strain patterns in the normal human left ventricle: characterization with tagged MR imaging. , 2000, Radiology.

[44]  Naide Oscillometry in diagnosis of arteriosclerosis of the lower extremities , 1939 .

[45]  Wei Tech Ang,et al.  Automatic Identification of Systolic Time Intervals in Seismocardiogram , 2016, Scientific Reports.

[46]  N B Ingels,et al.  Measurement of Midwall Myocardial Dynamics in Intact Man by Radiography of Surgically Implanted Markers , 1975, Circulation.

[47]  J. Voigt,et al.  Mechanical dispersion assessed by myocardial strain in patients after myocardial infarction for risk prediction of ventricular arrhythmia. , 2010, JACC. Cardiovascular imaging.

[48]  Shuvo Roy,et al.  Using Ballistocardiography to Monitor Left Ventricular Function in Heart Failure Patients , 2016 .

[49]  S. Steinhubl,et al.  Novel wireless devices for cardiac monitoring. , 2014, Circulation.

[50]  A. Weissler,et al.  Systolic Time Intervals in Heart Failure in Man , 1968, Circulation.

[51]  Y. Fung,et al.  Transmural Myocardial Deformation in the Canine Left Ventricle: Normal in Vivo Three‐Dimensional Finite Strains , 1985, Circulation research.

[52]  Andreas Espinoza,et al.  Assessment of 3D motion increases the applicability of accelerometers for monitoring left ventricular function. , 2015, Interactive cardiovascular and thoracic surgery.

[53]  Timo Knuutila,et al.  Atrial Fibrillation Detection via Accelerometer and Gyroscope of a Smartphone , 2018, IEEE Journal of Biomedical and Health Informatics.

[54]  Steffen Leonhardt,et al.  Automatic Detection of Atrial Fibrillation in Cardiac Vibration Signals , 2013, IEEE Journal of Biomedical and Health Informatics.

[55]  John M. Zanetti,et al.  Seismocardiography: a technique for recording precordial acceleration , 1991, [1991] Computer-Based Medical Systems@m_Proceedings of the Fourth Annual IEEE Symposium.

[56]  Eero Lehtonen,et al.  Automated Detection of Atrial Fibrillation Based on Time–Frequency Analysis of Seismocardiograms , 2017, IEEE Journal of Biomedical and Health Informatics.

[57]  D. Altman,et al.  STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT , 1986, The Lancet.

[58]  Gordon Malouf,et al.  Estimation of heart rate during sleep measured from a gyroscope embedded in a CPAP mask , 2016, 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES).

[59]  Bozhenko Bs [Seismocardiography--a new method in the study of functional conditions of the heart]. , 1961 .

[60]  Ari Paasio,et al.  A new algorithm for segmentation of cardiac quiescent phases and cardiac time intervals using seismocardiography , 2015, International Conference on Graphic and Image Processing.

[61]  L A Taber,et al.  Mechanics of ventricular torsion. , 1996, Journal of biomechanics.