Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors

[1]  E. Pauw,et al.  Isolation and characterization of Ts19 Fragment II, a new long-chain potassium channel toxin from Tityus serrulatus venom , 2016, Peptides.

[2]  F. Gozzo,et al.  [des-Arg1]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom , 2016, Peptides.

[3]  J. Tytgat,et al.  Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages. , 2015, Biochimie.

[4]  J. Tytgat,et al.  A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms , 2015, Neuropharmacology.

[5]  Y. Ahn,et al.  Antiviral Activity and Possible Mechanism of Action of Constituents Identified in Paeonia lactiflora Root toward Human Rhinoviruses , 2015, PloS one.

[6]  C. Sorgi,et al.  PPAR-γ activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production. , 2015, Toxicon : official journal of the International Society on Toxinology.

[7]  E. Kalapothakis,et al.  Molecular and functional characterization of metalloserrulases, new metalloproteases from the Tityus serrulatus venom gland. , 2014, Toxicon : official journal of the International Society on Toxinology.

[8]  Kwan-Kyu Park,et al.  Protective effect of melittin against inflammation and apoptosis on Propionibacterium acnes-induced human THP-1 monocytic cell. , 2014, European journal of pharmacology.

[9]  J. Tytgat,et al.  Electrophysiological Characterization of Ts6 and Ts7, K+ Channel Toxins Isolated through an Improved Tityus serrulatus Venom Purification Procedure , 2014, Toxins.

[10]  C. Sorgi,et al.  TLR2, TLR4 and CD14 Recognize Venom-Associated Molecular Patterns from Tityus serrulatus to Induce Macrophage-Derived Inflammatory Mediators , 2014, PloS one.

[11]  A. Almaaytah,et al.  Scorpion venom peptides with no disulfide bridges: A review , 2014, Peptides.

[12]  E. Arantes,et al.  Scorpion Venom Research Around the World: Tityus serrulatus , 2014 .

[13]  E. Arantes,et al.  Scorpionism and dangerous species of Brazil , 2014 .

[14]  Ran Wei,et al.  Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities. , 2013, Biochimie.

[15]  Qosay A. E. Al-Balas,et al.  Mauriporin, a Novel Cationic α-Helical Peptide with Selective Cytotoxic Activity Against Prostate Cancer Cell Lines from the Venom of the Scorpion Androctonus mauritanicus , 2013, International Journal of Peptide Research and Therapeutics.

[16]  C. Sorgi,et al.  Ts6 and Ts2 from Tityus serrulatus venom induce inflammation by mechanisms dependent on lipid mediators and cytokine production. , 2013, Toxicon : official journal of the International Society on Toxinology.

[17]  E. Kalapothakis,et al.  Transcriptome analysis of the Tityus serrulatus scorpion venom gland , 2012 .

[18]  Manoj Kumar,et al.  AVPpred: collection and prediction of highly effective antiviral peptides , 2012, Nucleic Acids Res..

[19]  J. Tytgat,et al.  Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom , 2012, The FEBS journal.

[20]  Lei Zhang,et al.  Characterization of BmKbpp, a multifunctional peptide from the Chinese scorpion Mesobuthus martensii Karsch: Gaining insight into a new mechanism for the functional diversification of scorpion venom peptides , 2012, Peptides.

[21]  J. Tytgat,et al.  Purification and characterization of Ts15, the first member of a new α-KTX subfamily from the venom of the Brazilian scorpion Tityus serrulatus. , 2011, Toxicon : official journal of the International Society on Toxinology.

[22]  C. Sorgi,et al.  Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators. , 2011, Toxicon : official journal of the International Society on Toxinology.

[23]  P. Farrell,et al.  A portable device for the electrical extraction of scorpion venom. , 2011, Toxicon.

[24]  S. Guatimosim,et al.  Structure-function studies of Tityus serrulatus Hypotensin-I (TsHpt-I): A new agonist of B(2) kinin receptor. , 2010, Toxicon : official journal of the International Society on Toxinology.

[25]  R. C. Rodríguez de la Vega,et al.  Mining on scorpion venom biodiversity. , 2010, Toxicon : official journal of the International Society on Toxinology.

[26]  F. Verdonck,et al.  Parabutoporin, a cationic amphipathic peptide from scorpion venom: much more than an antibiotic. , 2010, Toxicon : official journal of the International Society on Toxinology.

[27]  M. H. Borges,et al.  Tityus serrulatus venom peptidomics: assessing venom peptide diversity. , 2008, Toxicon : official journal of the International Society on Toxinology.

[28]  W. Lourenço Parthenogenesis in scorpions: some history - new data , 2008 .

[29]  L. Possani,et al.  Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species. , 2007, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[30]  Adriano Barbosa-Silva,et al.  Moving pieces in a taxonomic puzzle: venom 2D-LC/MS and data clustering analyses to infer phylogenetic relationships in some scorpions from the Buthidae family (Scorpiones). , 2006, Toxicon : official journal of the International Society on Toxinology.

[31]  J. de Vente,et al.  Indirect activation of neuronal noncapacitative Ca2+ entry is the final step involved in the neurotoxic effect of Tityus serrulatus scorpion β‐toxin , 2006, The European journal of neuroscience.

[32]  Yong-hui Shi,et al.  Direct spectrophotometric measurement of angiotensin I-converting enzyme inhibitory activity for screening bioactive peptides. , 2005, Journal of pharmaceutical and biomedical analysis.

[33]  G. Corzo,et al.  Scorpion Venom Peptides without Disulfide Bridges , 2005, IUBMB life.

[34]  Nikolaj Blom,et al.  Prediction of proprotein convertase cleavage sites. , 2004, Protein engineering, design & selection : PEDS.

[35]  L. Faccioli,et al.  Time course of acute-phase response induced by Tityus serrulatus venom and TsTX-I in mice. , 2003, International immunopharmacology.

[36]  F. Verdonck,et al.  Cationic peptides from scorpion venom can stimulate and inhibit polymorphonuclear granulocytes. , 2002, Toxicon : official journal of the International Society on Toxinology.

[37]  A. Torres-Larios,et al.  Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus. , 2000, European journal of biochemistry.

[38]  F. F. Carvalho,et al.  Neurotoxic effects of three fractions isolated from Tityus serrulatus scorpion venom. , 2000, Pharmacology & toxicology.

[39]  M. Dathe,et al.  Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells. , 1999, Biochimica et biophysica acta.

[40]  T. Chou,et al.  Stimulation of TNF‐α, IL‐1β and nitrite release from mouse cultured spleen cells and lavaged peritoneal cells by mastoparan M , 1999 .

[41]  J. Cloudsley-Thompson DISCOVERY OF A SEXUAL POPULATION OF TITYUS SERRULATUS, ONE OF THE MORPHS WITHIN THE COMPLEX TITYUS STIGMURUS (SCORPIONES, BUTHIDAE) , 1999 .

[42]  T. Chou,et al.  Stimulation of TNF-alpha, IL-1beta and nitrite release from mouse cultured spleen cells and lavaged peritoneal cells by mastoparan M. , 1999, Immunology and cell biology.

[43]  D. M. Morgan,et al.  Tetrazolium (MTT) assay for cellular viability and activity. , 1998, Methods in molecular biology.

[44]  H. Rochat,et al.  A bradykinin-potentiating peptide (peptide K12) isolated from the venom of Egyptian scorpion Buthus occitanus , 1995, Peptides.

[45]  S. Johnston,et al.  Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates , 1994, Antimicrobial Agents and Chemotherapy.

[46]  P. Bougis,et al.  Biochemical, pharmacological and genomic characterisation of Ts IV, an α‐toxin from the venom of the South American scorpion Tityus serrulatus , 1994, FEBS letters.

[47]  E. W. Alves,et al.  Peptide T, a novel bradykinin potentiator isolated from Tityus serrulatus scorpion venom. , 1993, Toxicon : official journal of the International Society on Toxinology.

[48]  J. Tytgat,et al.  Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs , 1992, Neuron.

[49]  F. Hayden,et al.  In vitro studies of the antirhinovirus activity of soluble intercellular adhesion molecule-1 , 1992, Antimicrobial Agents and Chemotherapy.

[50]  Molecular cloning and nucleotide sequence analysis of a cDNA encoding the main β‐neurotoxin from the venom of the South American scorpion Tityus serrulatus , 1992, FEBS letters.

[51]  I. Shalit,et al.  Augmentation of the antibacterial activity of magainin by positive-charge chain extension , 1992, Antimicrobial Agents and Chemotherapy.

[52]  S R Tannenbaum,et al.  Nitrate biosynthesis in man. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[53]  P. Edman,et al.  A protein sequenator. , 1967, European journal of biochemistry.

[54]  F. A. Matthiesen,et al.  PARTHENOGENESIS IN SCORPIONS , 1962 .