A cell-based bicistronic lentiviral reporter system for identification of inhibitors of the hepatitis C virus internal ribosome entry site.

[1]  Michael Niepmann,et al.  microRNA-122 stimulates translation of hepatitis C virus RNA , 2008, The EMBO journal.

[2]  E. Martínez-Salas,et al.  Riboproteomic analysis of polypeptides interacting with the internal ribosome‐entry site element of foot‐and‐mouth disease viral RNA , 2008, Proteomics.

[3]  A. Cahour,et al.  Hepatitis C virus internal ribosome entry site‐mediated translation is stimulated by cis‐acting RNA elements and trans‐acting viral factors , 2008, The FEBS journal.

[4]  M. Stack,et al.  Polypyrimidine Tract-binding Protein (PTB) Differentially Affects Malignancy in a Cell Line-dependent Manner* , 2008, Journal of Biological Chemistry.

[5]  Christopher W. J. Smith,et al.  Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content , 2008, PloS one.

[6]  K. Davies,et al.  Modified patient stem cells as prelude to autologous treatment of muscular dystrophy. , 2007, Cell stem cell.

[7]  J. Pawlotsky,et al.  Interferon-based therapy of hepatitis C. , 2007, Advanced drug delivery reviews.

[8]  Darius Moradpour,et al.  Replication of hepatitis C virus , 2007, Nature Reviews Microbiology.

[9]  M. Alter,et al.  Epidemiology of hepatitis C virus infection. , 2007, World journal of gastroenterology.

[10]  J. Pawlotsky,et al.  The hepatitis C virus life cycle as a target for new antiviral therapies. , 2007, Gastroenterology.

[11]  T. Kafri,et al.  Gene delivery by lentivirus vectors , 2007, Molecular biotechnology.

[12]  D. Samuel,et al.  Clinical and therapeutic implications of hepatitis C virus compartmentalization. , 2006, Gastroenterology.

[13]  G. Margison,et al.  Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI , 2006, Virology Journal.

[14]  F. Cosset,et al.  Lentiviral transduction of human hematopoietic cells by HIV‐1‐ and SIV‐based vectors containing a bicistronic cassette driven by various internal promoters , 2005, The journal of gene medicine.

[15]  R. Francesco,et al.  Challenges and successes in developing new therapies for hepatitis C , 2005, Nature.

[16]  R. Bartenschlager,et al.  Production of infectious hepatitis C virus in tissue culture from a cloned viral genome , 2005, Nature Medicine.

[17]  S. Thung,et al.  Interferons α, β, γ each inhibit hepatitis C virus replication at the level of internal ribosome entry site‐mediated translation , 2005 .

[18]  D. Samuel,et al.  Compartmentalization of Hepatitis C Virus Genotypes between Plasma and Peripheral Blood Mononuclear Cells , 2005, Journal of Virology.

[19]  J. Lavergne,et al.  Hepatitis C Virus Core Protein Acts as a trans-Modulating Factor on Internal Translation Initiation of the Viral RNA* , 2005, Journal of Biological Chemistry.

[20]  J. Pawlotsky,et al.  Future Therapies for Hepatitis C , 2005, Antiviral therapy.

[21]  K. Nash,et al.  Green fluorescent protein: green cells do not always indicate gene expression , 2004, Gene Therapy.

[22]  Saumitra Das,et al.  Targeting internal ribosome entry site (IRES)-mediated translation to block hepatitis C and other RNA viruses. , 2004, FEMS microbiology letters.

[23]  S. Ngoi,et al.  Exploiting internal ribosome entry sites in gene therapy vector design. , 2004, Current gene therapy.

[24]  C. Staedel,et al.  A promoter activity is present in the DNA sequence corresponding to the hepatitis C virus 5' UTR. , 2003, Nucleic acids research.

[25]  P. D. Felipe.  Polycistronic Viral Vectors , 2002 .

[26]  P. Mangeot,et al.  High levels of transduction of human dendritic cells with optimized SIV vectors. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

[27]  R. Jubin.  Hepatitis C IRES: translating translation into a therapeutic target. , 2001, Current opinion in molecular therapeutics.

[28]  R. Brady,et al.  Development of Multigene and Regulated Lentivirus Vectors , 2000, Journal of Virology.

[29]  J. Toulmé,et al.  Comparative Analysis of Translation Efficiencies of Hepatitis C Virus 5′ Untranslated Regions among Intraindividual Quasispecies Present in Chronic Infection: Opposite Behaviors Depending on Cell Type , 2000, Journal of Virology.

[30]  P. Mangeot,et al.  Development of Minimal Lentivirus Vectors Derived from Simian Immunodeficiency Virus (SIVmac251) and Their Use for Gene Transfer into Human Dendritic Cells , 2000, Journal of Virology.

[31]  H. Mizuguchi,et al.  IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

[32]  J. Münch,et al.  Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus. , 2000, Human gene therapy.

[33]  D. Trono,et al.  Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery , 1998, Journal of Virology.

[34]  F. Gage,et al.  Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[35]  F. Gage,et al.  In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector , 1996, Science.

[36]  M. Kay,et al.  Pseudotransduction of hepatocytes by using concentrated pseudotyped vesicular stomatitis virus G glycoprotein (VSV-G)-Moloney murine leukemia virus-derived retrovirus vectors: comparison of VSV-G and amphotropic vectors for hepatic gene transfer , 1996, Journal of virology.

[37]  J. Burns,et al.  A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[38]  G. Butler-Browne,et al.  Clones of human satellite cells can express in vitro both fast and slow myosin heavy chains. , 1994, Developmental biology.

[39]  H. Fleury,et al.  Seven nucleotide changes characteristic of the hepatitis C virus genotype 3 5' untranslated region: correlation with reduced in vitro replication. , 2008, The Journal of general virology.

[40]  H. Agut,et al.  Differential distribution and internal translation efficiency of hepatitis C virus quasispecies present in dendritic and liver cells. , 2003, Blood.

[41]  S. Lemon,et al.  Internal ribosome entry site-mediated translation in hepatitis C virus replication. , 2000, Current topics in microbiology and immunology.