Comparison of cardiac-induced endogenous fields and power frequency induced exogenous fields in an anatomical model of the human body.

Time-domain potentials measured at 64 points on the surface of a large canine heart, considered comparable with those of a human heart, were used to calculate the electric fields and current densities within various organs of the human body. A heterogeneous volume conductor model of an adult male with a resolution of approximately 6 mm3 and 30 segmented tissue types was used along with the admittance method and successive over-relaxation to calculate the voltage distribution throughout the torso and head as a function of time. From this time-domain voltage description, values of [E(t)] and [J(t)] were obtained, allowing for maximum values to be found within the given tissues of interest. Frequency analysis was then used to solve for [E(f)] and [J(f)] in the various organs, so that average, minimum and maximum values within specific bandwidths (0-40, 40-70 and 70-100 Hz) could be analysed. A comparison was made between the computed results and measured data from both EKG waveforms and isopotential surface maps for validation, with good agreement in both amplitude and shape between the computed and measured results. These computed endogenous fields were then compared with exogenous fields induced in the body from a 60 Hz high-voltage power line and a 60 Hz uniform magnetic field of 1 mT directed from the front to the back of the body. The high-voltage power line EMFs and 1 mT magnetic field were used as 'bench' marks for comparison with several safety guidelines for power frequency (50/60 Hz) EMF exposures. The endogenous electric fields and current densities in most of the tissues (except for organs in close proximity to the heart, for example lungs, liver, etc) in the frequency band 40-70 Hz were found to be considerably smaller, between 5% and 10%, than those induced in the human body by the electric and magnetic fields generated by the 60 Hz sources described above.

[1]  J. G. Webster,et al.  Impedance of Skeletal Muscle from 1 Hz to 1 MHz , 1984, IEEE Transactions on Biomedical Engineering.

[2]  D. Miller,et al.  Comparison of cardiac and 60 Hz magnetically induced electric fields measured in anesthetized rats. , 1997, Bioelectromagnetics.

[3]  K. Foster,et al.  Dielectric properties of tissues and biological materials: a critical review. , 1989, Critical reviews in biomedical engineering.

[4]  A. Goldberger Clinical Electrocardiography: A Simplified Approach , 1977 .

[5]  H. Wachtel Comparison of Endogenous Currents in and Around Cells with Those Induced by Exogenous Extremely Low Frequency Magnetic Fields , 1995 .

[6]  Yongmin Kim,et al.  On the contribution of volume currents to the total magnetic field resulting from the heart excitation process: a simulation study , 1996, IEEE Transactions on Biomedical Engineering.

[7]  Y. Rudy,et al.  Noninvasive recovery of epicardial potentials in a realistic heart-torso geometry. Normal sinus rhythm. , 1990, Circulation research.

[8]  C R Johnson,et al.  A computer model for the study of electrical current flow in the human thorax. , 1992, Computers in biology and medicine.

[9]  D W Armitage,et al.  Radiofrequency-induced hyperthermia: computer simulation of specific absorption rate distributions using realistic anatomical models. , 1983, Physics in medicine and biology.

[10]  A. Ahlbom Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz) , 1998 .

[11]  P Nopp,et al.  Dielectric properties of lung tissue as a function of air content. , 1993, Physics in medicine and biology.

[12]  R. Nuccitelli Endogenous ionic currents and DC electric fields in multicellular animal tissues. , 1992, Bioelectromagnetics.

[13]  S. Rush,et al.  Resistivity of Body Tissues at Low Frequencies , 1963, Circulation research.

[14]  L. Weixue,et al.  Computer simulation of epicardial potentials using a heart-torso model with realistic geometry. , 1996, IEEE transactions on bio-medical engineering.

[15]  G. W. Hoffler,et al.  A spectral analysis of the normal resting electrocardiogram. , 1973, IEEE transactions on bio-medical engineering.

[16]  O. Gandhi,et al.  Induced electric currents in models of man and rodents from 60 Hz magnetic fields , 1994, IEEE Transactions on Biomedical Engineering.

[17]  Y. Rudy,et al.  The use of temporal information in the regularization of the inverse problem of electrocardiography , 1992 .

[18]  J. Herbertz Comment on the ICNIRP guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz) , 1998, Health physics.

[19]  O. Gandhi Some numerical methods for dosimetry: Extremely low frequencies to microwave frequencies , 1995 .

[20]  W. S. Snyder,et al.  Report of the task group on reference man , 1979, Annals of the ICRP.

[21]  Daming Wei,et al.  Comparative simulation of excitation and body surface electrocardiogram with isotropic and anisotropic computer heart models , 1995, IEEE Transactions on Biomedical Engineering.