论文信息 - Synthesis of 2‐Aminochromene Derivatives Catalyzed by KF/Al2O3

Synthesis of 2‐Aminochromene Derivatives Catalyzed by KF/Al2O3

Abstract A series of 2‐aminochromene derivatives include 2‐aminobenzo‐[h]chromene and naphtha[1,2‐b;6,5‐b′]dipyrans derivatives were synthesized from arylaldehyde, malononitrile or ethyl cyanoacetate with 1‐naphthol or 1,5‐naphthalenediol in refluxing ethyl alcohol catalyzed by KF‐Al2O3. The structure of the products was confirmed by X‐ray analysis.

D. Shi | Gao‐feng Wang | Xiang-Shan Wang | Hui‐zhen Yu | S. Tu

[1] D. Shi,et al. A Convenient Synthesis of 5-Oxo-5,6,7,8-tetrahydro-4 H -benzo-[b]-pyran Derivatives Catalyzed by KF-Alumina , 2003 .

[2] D. Shi,et al. A Convenient Synthesis of (3-Oxo-1,3-diaryl) Propylpropanedinitrile Catalyzed by Kf-Alumina , 1998 .

[3] M. H. Elnagdi,et al. Nitriles in heterocyclic synthesis: Novel syntheses of benzo[ b ]pyrans, naphtho[1,2- b ]pyrans, naphtho[2,1- b ]pyrans, pyrano[3,2- h ]quinolines and pyrano[3,2- c ]quinolines , 1988 .

[4] J. Clark,et al. Fluoride-alumina reagents: the active basic species , 1987 .

[5] M. H. Elnagdi,et al. Nitriles in heterocyclic synthesis: novel synsthesis of benzo[c]-coumarin and of benzo[c]pyrano[3,2-c]quinoline derivatives , 1987 .

[6] J. Clark,et al. Alumina-supported fluoride reagents for organic synthesis: optimisation of reagent preparation and elucidation of the active species , 1986 .

[7] T. Ando,et al. Fluoride Salts on Alumina as Reagents for Alkylation of Phenols and Alcohols , 1982 .