A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins.
暂无分享,去创建一个
[1] W. Bender,et al. A Drosophila model of Parkinson's disease , 2000, Nature.
[2] M. Citron,et al. Both Familial Parkinson’s Disease Mutations Accelerate α-Synuclein Aggregation* , 1999, The Journal of Biological Chemistry.
[3] R. D. Carlson,et al. A simple method for the preparation of homogeneous phospholipid vesicles. , 1977, Biochemistry.
[4] A. Kimmel,et al. Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. , 1999, Seminars in cell & developmental biology.
[5] K. Wüthrich. NMR of proteins and nucleic acids , 1988 .
[6] P. S. Kim,et al. High-resolution protein design with backbone freedom. , 1998, Science.
[7] Olaf Riess,et al. AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease , 1998, Nature Genetics.
[8] A. Lupas. Coiled coils: new structures and new functions. , 1996, Trends in biochemical sciences.
[9] A. Bax,et al. Empirical correlation between protein backbone conformation and C.alpha. and C.beta. 13C nuclear magnetic resonance chemical shifts , 1991 .
[10] P. Højrup,et al. α-Synuclein Binds to Tau and Stimulates the Protein Kinase A-catalyzed Tau Phosphorylation of Serine Residues 262 and 356* , 1999, The Journal of Biological Chemistry.
[11] D. Clayton,et al. Synucleins in synaptic plasticity and neurodegenerative disorders , 1999, Journal of neuroscience research.
[12] R. Kammerer,et al. Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer , 2001, Nature Structural Biology.
[13] Nobutaka Hattori,et al. Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease , 2001, Science.
[14] N. Guex,et al. SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling , 1997, Electrophoresis.
[15] G. Anantharamaiah,et al. The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function. , 1992, Journal of lipid research.
[16] L. Dure. A repeating 11-mer amino acid motif and plant desiccation. , 1993, The Plant journal : for cell and molecular biology.
[17] Robert L. Nussbaum,et al. Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease , 1997 .
[18] P. Lansbury,et al. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. , 1996, Biochemistry.
[19] Peter T. Lansbury,et al. Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct , 2001, Science.
[20] T. Close,et al. The binding of Maize DHN1 to Lipid Vesicles. Gain of Structure and Lipid Specificity1 , 2003, Plant Physiology.
[21] Maria Jesus Martin,et al. The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 , 2003, Nucleic Acids Res..
[22] Rebecca A. Betensky,et al. α-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[23] D. Eisenberg,et al. A census of protein repeats. , 1999, Journal of molecular biology.
[24] G. Anantharamaiah,et al. Computer programs to identify and classify amphipathic alpha helical domains. , 1992, Journal of lipid research.
[25] Ad Bax,et al. Four-Dimensional 15N-Separated NOESY of Slowly Tumbling Perdeuterated 15N-Enriched Proteins. Application to HIV-1 Nef , 1995 .
[26] W Baumeister,et al. Hyperthermostable surface layer protein tetrabrachion from the archaebacterium Staphylothermus marinus: evidence for the presence of a right-handed coiled coil derived from the primary structure. , 1996, Journal of molecular biology.
[27] Reinhard Jahn,et al. A Broken α-Helix in Folded α-Synuclein* , 2003, The Journal of Biological Chemistry.
[28] P. S. St George-Hyslop,et al. α-Synuclein Membrane Interactions and Lipid Specificity* , 2000, The Journal of Biological Chemistry.
[29] J. Engler,et al. Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[30] M L Johnson,et al. Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. , 1981, Biophysical journal.
[31] R. Scheller,et al. Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[32] J. Payton,et al. Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells. , 2001, Brain research. Molecular brain research.
[33] Heidi Phillips,et al. Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System , 2000, Neuron.
[34] D. Eliezer,et al. Residual Structure and Dynamics in Parkinson's Disease-associated Mutants of α-Synuclein* , 2001, The Journal of Biological Chemistry.
[35] F. Crick,et al. The packing of α‐helices: simple coiled‐coils , 1953 .
[36] F. Richards,et al. Relationship between nuclear magnetic resonance chemical shift and protein secondary structure. , 1991, Journal of molecular biology.
[37] David F. Clayton,et al. Characterization of a novel protein regulated during the critical period for song learning in the zebra finch , 1995, Neuron.
[38] G. Anantharamaiah,et al. Experimental and computational studies of the interactions of amphipathic peptides with lipid surfaces , 2002 .
[39] L. Petrucelli,et al. α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins , 1999, The Journal of Neuroscience.
[40] Richard Paylor,et al. Synaptic Vesicle Depletion Correlates with Attenuated Synaptic Responses to Prolonged Repetitive Stimulation in Mice Lacking α-Synuclein , 2002, The Journal of Neuroscience.
[41] P. Worley,et al. Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions , 1999, Nature Genetics.
[42] R. Nussbaum,et al. α-Synuclein Is Phosphorylated by Members of the Src Family of Protein-tyrosine Kinases* , 2001, The Journal of Biological Chemistry.
[43] M. L. Schmidt,et al. α-Synuclein in Lewy bodies , 1997, Nature.
[44] D. Eliezer,et al. Conformational properties of alpha-synuclein in its free and lipid-associated states. , 2001, Journal of molecular biology.
[45] A. Jonas,et al. Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes* , 1998, The Journal of Biological Chemistry.
[46] J. Trojanowski,et al. Phosphorylated α-Synuclein Is Ubiquitinated in α-Synucleinopathy Lesions* , 2002, The Journal of Biological Chemistry.
[47] L. Mucke,et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. , 2000, Science.
[48] P. Lansbury,et al. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[49] Makoto Hashimoto,et al. β-Synuclein Inhibits α-Synuclein Aggregation A Possible Role as an Anti-Parkinsonian Factor , 2001, Neuron.
[50] J. Killian,et al. How proteins adapt to a membrane-water interface. , 2000, Trends in biochemical sciences.
[51] Anthony E. Klon,et al. A Detailed Molecular Belt Model for Apolipoprotein A-I in Discoidal High Density Lipoprotein* , 1999, The Journal of Biological Chemistry.
[52] J. Benovic,et al. Synucleins Are a Novel Class of Substrates for G Protein-coupled Receptor Kinases* , 2000, The Journal of Biological Chemistry.
[53] L. Meijer,et al. Constitutive Phosphorylation of the Parkinson's Disease Associated α-Synuclein* , 2000, The Journal of Biological Chemistry.
[54] Peter T. Lansbury,et al. Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease , 1998, Nature Medicine.
[55] J. Johnson,et al. Amphitropic proteins: regulation by reversible membrane interactions (review). , 1999, Molecular membrane biology.
[56] A. Morris,et al. Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins. , 1998, Biochemistry.
[57] Anthony E. Klon,et al. Molecular belt models for the apolipoprotein A-I Paris and Milano mutations. , 2000, Biophysical Journal.